IZTECH Research Centers Collection / İYTE Araştırma Merkezleri Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/11147/2636
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Article Citation - WoS: 11Citation - Scopus: 11Cfd Characteristics of Refrigerated Trailers and Improvement of Airflow for Preserving Perishable Foods(MDPI, 2019) Yildiz,T.When preserving perishable goods, maintaining a constant temperature over the cold supply chain is essential. Therefore, refrigerated vehicles are an important part of the cold supply chain system. However, many traditional refrigerated cargo systems are not designed to support the homogeneity of the temperature inside cargo trailers. Indeed, refrigerating equipment is usually placed on one side of transportation systems as this is considered to be more practical. Such a configuration thus leads to significant temperature differences in the two distinct parts of a refrigerated cargo trailer, which might affect the quality, safety, and shelf life of perishable foods. This research aims to improve the temperature distribution of refrigerated trailers. In this study, it is highlighted that in the most commonly used traditional refrigerated trailer models, lower air velocity and higher product temperature are observed at the rear. There is also a partial product chilling risk at the front of the refrigerated trailer. This study investigates and reports significant differences among the three airflow design models of refrigerated cargo systems by applying turbulence flow, heat, and mass transfer models. The analyses of these three models reveal that significant improvement could be achieved by applying the proper arrangements of inlets on the ceiling of the trailer body. © 2019 by the author.Article Citation - WoS: 11Citation - Scopus: 17Design and Analysis of a Lightweight Composite Shipping Container Made of Carbon Fiber Laminates(MDPI, 2019) Yildiz,T.The literature indicates that a 20% reduction in the weight of empty 40-foot shipping containers would result in $28 billion of fuel savings, along with a 3.6 exajoule reduction in the energy demand over containers’ 15-year lifetime. Decreasing the energy demand and thereby greenhouse gas emissions by utilizing lightweight shipping containers has been an unexplored strategy. In this regard, this study investigates the possibility of further reducing the weight of an empty container without compromising the structural integrity, strength, and function of a traditional steel container. This research finds that up to an 80% reduction in weight is possible by producing shipping containers with composite materials. This research presents the new design of a 40-foot container made of carbon fiber laminates. The tare weight of a traditional 40-foot shipping container is around 3750 kg. On the contrary, in this research, the weight of a composite design of the same container is calculated to be around 822 kg. Additional tests with various loads, such as lifting the container and stacking loads onto the composite container, are performed to explore the strength and buckling issues of the design presented in this study. The analyses reveal that the composite shipping container is a highly promising candidate for reducing greenhouse gas emissions, providing fuel savings and thus reducing the operational costs of transportation. © 2019 by the author.Article Citation - WoS: 10Citation - Scopus: 9Bi̇yomalzemelerden İ̇zole Edi̇len Staphylococcus Epidermidis Suşlarinin Yüzey Özelli̇kleri̇ni̇n Beli̇rlenmesi̇(Ankara Mikrobiyoloji Derneği, 2010) Sudağıdan, Mert; Erdem, İlker; Çavuşoğlu, Cengiz; Çiftçioğlu, MuhsinThe surface properties of bacteria play an important role on adhesion to the biomaterial surface. In this study, the surface properties of Staphylococcus epidermidis strains isolated from clinically used polymeric biomaterial surfaces were investigated on the basis of zeta potential, hydrophobicity and surface topography. A total of 10 S.epidermidis strains isolated from intravenous catheters (n= 5), endotracheal tubes (n= 3) and central venous catheters (n= 2) which were used in the patients of pulmonary Intensive Care Unit, Ege University Medical Faculty Hospital, were included to the study. Seven of those isolates were biofilm producers, inhabiting biofilm genes, 2 were non-biofilm producers, however, inhabiting biofilm genes, and 1 was non-biofilm producer, inhabiting no biofilm genes. Zeta potential analysis have been performed in 3 different buffers (phosphate-buffered saline, 1 mM potassium chloride and 1 mM potassium phosphate buffer) and at different pH values (pH 4.1-8.2), in order to simulate in vivo environment of the biomaterials. Hydrophobicities of the strains were examined by bacterial adhesion to hydrocarbon (BATH) test and the surface topography of biofilms and slime layers were visualized by atomic force microscopy (AFM) and scanning electron microscopy (SEM) methods. It was found that all strains have negative zeta potential values (surface charge) in all buffers and pH values. In hydrophobicity analysis, the highest value (86%) was determined for non-biofilm forming S.epidermidis strain YT-169b (endotracheal tube isolate) and the lowest hydrophobicity (2.5%) was determined for biofilm forming S.epidermidis strain YT-212 (central venous catheter isolate). Biofilm and slime layers of the strains were imaginated by AFM and SEM analysis in ?m scale. SEM analysis showed that bacteria highly adhered to rough surfaces on biomaterial surfaces and the produced slime layers covered the surface of bacteria. In conclusion, elucidating the surface properties of opportunistic pathogens in different physiologic buffers will give important clues for the production of non-adhesive materials and antibacterial surfaces for those bacteria. It was also estimated that designing the surface of the biomaterial to have negative surface charge in the body and to be as smooth as possible will hamper biofilm formation.Article Citation - WoS: 19Citation - Scopus: 18Biyomalzeme Yüzeylerinden İzole Edilen Metisiline Dirençli Staphylococcus Aureus Suşlarında Virülans Genlerinin Araştırılması(Ankara Microbiology Society, 2008) Sudağıdan, Mert; Çavuşoğlu, Cengiz; Bacakoğlu, FezaStafilokoklar, biyomalzeme kaynaklı nozokomiyal enfeksiyonların en önemli etkenlerindendir. Bu çalışmada, Göğüs Hastalıkları Yoğun Bakım Ünitesi (YBÜ)'nde yatan 48 hastada kullanılan polimerik biyomalzeme yüzeylerinden izole edilen metisiline dirençli 11 Staphylococcus aureus suşunda virülans genlerinin varlığının saptanması ve bunların bazılarının fenotipik ifadelerinin araştırılması amaçlanmıştır. Çalışmamızda polimeraz zincir reaksiyonu (PCR) ile özgül primerler kullanılarak, bağlanma ve biyofilm oluşumundan sorumlu genler (icaA, icaC, bap), metisilin direnç geni (mecA), enterotoksin A-E üretiminden sorumlu genler (sea, seb, sec, sed, see), toksik şok sendromu toksini geni [tst), eksfoliatif toksin A ve B genleri (eta ve etb), alfa ve beta-hemolizin genleri (hla ve hlb), stafilokokal ekzotoksin benzeri protein-1 geni (sef1), proteaz genleri (sspA, sspB, aur, serine proteaz geni), lipaz geni (geh) ve regülatör genler (sarA ve agrCA) araştırılmıştır. Ayrıca suşların fenotipik olarak biyofilm oluşturma, antibiyotik duyarlılık, proteaz ve lipaz üretimi gibi özellikleri de değerlendirilmiştir. Biyofilm testlerinde, biyofilm yapan ve "slime" üreten suşlara rastlanmamış, ancak tüm suşların biyofilm yapımında rol oynayan icaA genine sahip olduğu bulunmuştur. Bununla birlikte biyofilm yapımında rol oynayan icaC ve bap genleri tespit edilememiştir. Tüm suşlarda mecA geninin varlığı saptanmış ve suşların hepsinin oksasilin, penisilin G ve gentamisine; 10'unun eritromisine ve dokuzunun da ofloksasine dirençli olduğu bulunmuştur. İzolatların tümü vankomisin, teikoplanin ve ko-trimoksazole duyarlı olarak saptanmıştır. Ekzotoksin ve regülatör genlerinin taranması sonucunda, suşların sea, seti, hla, hlb ve sarA genlerini taşıdığı belirlenmiştir. PCR ile tüm suşların, çalışılan bütün proteaz genlerine (sspA, sspB, aur ve serin proteaz geni) sahip olduğu görülmüş, ancak sütlü (skim milk ve milk agar) ve kazein ağarlarda yapılan proteaz üretimi testlerinde negatif sonuç alınmıştır. Lipaz üretiminin belirlenmesi için Tween 20, Tween 80 ve tributyrin içeren besiyerleri kullanılmış ve tüm suşlarda geç dönemde (inkübasyonun üçüncü günü) pozitif sonuç alınmasına karşın, izolatların hiçbirisinde lipaz üretiminden sorumlu geh geni bulunmamıştır. Sonuç olarak, biyomalzeme yüzeylerinden izole edilen S.aureus suşlarında, araştırılan virülans genlerinden bazılarının varlığı saptanmış, ancak bunların tam olarak fenotipe yansımadığı izlenmiştir. İzolat sayısının azlığına ve tüm genlerin ekspresyonlarının fenotipik olarak çalışılamamış olmasına rağmen, bu genlerin varlığının yoğun bakım hastalan için potansiyel bir risk teşkil edebileceği düşünülmüştür.Conference Object Citation - Scopus: 1Enterprise Systems Applications Development Plans To Build and Develop Robust and Environmentally Sensitive Green Logistics Systems Management Software(Springer Verlag, 2009) Yıldız, Türkay; Yercan, FundaWithin the concept of enterprise-wide development of environmentally sensitive systems' application modules to fully integrate all-in-one green logistics services principles have received much attention and consideration from practitioners, academia, and from the industry, for about more than a decade. However, by taking into the consideration of the multidisciplinary nature of the issue, large scale effective collaborative framework is needed to be developed. Therefore, utilization of UML diagrams, class definitions, defining class relationships, fields, tables, views, etc. so on play crucial roles in the design phases of the enterprise system. Thus, this article largely deals with the major logistics work processes and their interactions within the consideration of environmental engineering issues on business operations to address step-by-step process control mechanisms to provide necessary input to build robust-design and better implementation of the needed IT software backbone.Book Part Exergetic and Exergoeconomic Aspects of Ground-Source (geothermal) Heat Pumps in Turkey(Taylor & Francis, 2014) Hepbaşlı, Arif; Hancıoğlu Kuzgunkaya, EbruThe demand for energy has recently increased rapidly as a result of the world’s population increase and industrial growth. On the contrary, fossil fuel supply is declining due to depletion of the resources. Moreover, utilization of fossil fuel energy resources has resulted in adverse effects on the global environment. In this regard, there is an urgent need to implement the use of sustainable and environmentally clean energy sources. In this context, renewable energy sources, including geothermal sources, can play a critical role in meeting the energy demands of societies.Article Citation - WoS: 3Citation - Scopus: 4Evaluation of Multifunctional Hybrid Analogs for Stilbenes, Chalcones and Flavanones(Bentham Science Publishers, 2017) Çağır, Ali; Odacı, Burcu; Varol, Mehmet; Akçok, İsmail; Okur, Özgür; Koparal, Ayşe T.Aims: In this study, discovery of novel anticancer agents acting by more than one mechanism was aimed. Method: For this purpose, eleven previously synthesized simple-stilbene, chalcone, flavanone derivatives and 31 novel stilbene-fused chalcones and stilbene-fused flavanones were tested for their aromatase inhibition, anti-angiogenic and anti-proliferative properties in cancer (PC3, MCF-7) and healthy (HUVEC) cell lines. MTT cell viability assay was used to evaluate the anti-proliferative activities of the compounds. CYP19/MFC high-throughput screening kit (BD Biosciences, Oxford, UK) was used to search the aromatase inhibition properties and matrigel tube formation assay was applied to determine the anti-angiogenic activities. Results: Results indicate that the simple-chalcone and flavanone derivatives were more cytotoxic than the simple-stilbenes in the both cancer cell lines. In contrast, the simple-stilbene structures were much more effective at aromatase inhibition. The cytotoxicity profiles of stilbene-fused chalcones in cancer cells imply that these molecules mostly mimic the simple chalcone structures. On the other hand, flavanones lose their cytotoxic activities after becoming fused with stilbenes. Additionally, aromatase inhibition assays showed that stilbene-fused chalcones again do mimic the simple-chalcones but not simple-stilbenes and anti-angiogenic profiles of the tested molecules seem to be not related with stilbene fragments. Furthermore, stilbene-fused flavanones may mimic both simple-flavanones and simple-stilbenes depending upon the type and position of the substituent in their respective terminal aromatic rings.Article Citation - WoS: 3Citation - Scopus: 3Energy Performance Assessment in Terms of Primary Energy and Exergy Analyses of the Nursing Home and Rehabilitation Center(SAGE Publications Inc., 2019) Hancıoğlu Kuzgunkaya, EbruThis paper concerns with the energy analysis (based on primary energy) and exergy analysis of Narlıdere Nursing Home and Rehabilitation Center (NNHRC) in İzmir, Turkey that was chosen as a sample public building. The Center services as a nursing and rehabilitation center for the aged and it also includes a geriatric division operating as a hospital. The Center was analyzed using the actual energy consumption data derived from several energy audits. Energy efficiency (according to the primary energy ratio) and exergy efficiency of the facility were calculated to be 59% and 14%, respectively. The results have indicated that the exergy efficiencies of space heating and cooling have the lowest values compared with the other units of facility. Specific primary energy consumption and specific exergy consumption of the facility were found to be 271.91 kWh/m2 year and 290.23 kWh/m2 year, respectively. Sustainability index value of the overall NNHRC was found to be 1.621.Article Citation - WoS: 32Citation - Scopus: 30Geochemical and Hydrogeochemical Characteristics and Evolution of Kozaklı Geothermal Fluids, Central Anatolia, Turkey(Elsevier Ltd., 2019) Baba, Alper; Şener, Mehmet FurkanKozaklı is one of the most important areas of Central Anatolia in terms of geothermal potential and it is characterized by thrust and normal faults. These faults, accommodating deep circulation of hydrothermal fluids of meteoric origin, are the primary controls of the geothermal systems in this region. Chemical and isotopic composition of the hot springs and geothermal fluids was monitored throughout 2017. The surface temperature of the fluid ranges from 24.9 to 96 °C. The cold spring waters are mostly of the Ca-Mg−HCO3 type in the study area. Major element chemistry of the water reveals that the deep geothermal fluids are mostly of the Na-Ca-Cl-SO4 type while the shallow geothermal well waters are Ca-Na−HCO3 waters. Silica geothermometers suggest that the reservoir temperature ranges from 103 to 173 °C. Based on the δ18O–δD relationship, water samples have a high-altitude meteoric origin. Stable isotopic data indicate that the geothermal fluids are formed by local recharge and deep circulation of meteoric waters. The Rare Earth Elements and Yttrium (REY) composition showed that Eu, Ce and Y anomalies are related both to inheritance from geological host materials and the fractionation of these elements during water-rock interactions.Article Exergetic Analysis of a Continuous Bi-Axially Oriented Polypropylene (bopp) Film Unit in a Plastic Processing Plant(Inderscience Enterprises Ltd., 2009) Balta, M. Tolga; Hepbaşlı, Arif; Hancıoğlu, Ebru; Özcanlı, Şevket Cihangir; Yılmazer, Ertan; Yurdakul, İbrahim; Dişbudak, ÖzgürThis paper deals with an exergy analysis of the stretching process of bi-axially oriented polypropylene films using a hot oil coiler along with stretching and crystallising unit. Exergy destructions and efficiencies in each of the system components are calculated, while the exergy loss and flow diagram (the so-called Grassmann diagram) is presented for the transverse direction (TD) unit. The so-called functional (on the product or benefit/fuel basis) and universal (on the output/input basis) exergy efficiency values of the TD unit are calculated to be 26.40% and 28.46% at a recommended exhaust air relative humidity of 0.0098 kg water/kg air, respectively.