IZTECH Research Centers Collection / İYTE Araştırma Merkezleri Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/11147/2636
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Article Citation - WoS: 11Citation - Scopus: 11Cfd Characteristics of Refrigerated Trailers and Improvement of Airflow for Preserving Perishable Foods(MDPI, 2019) Yildiz,T.When preserving perishable goods, maintaining a constant temperature over the cold supply chain is essential. Therefore, refrigerated vehicles are an important part of the cold supply chain system. However, many traditional refrigerated cargo systems are not designed to support the homogeneity of the temperature inside cargo trailers. Indeed, refrigerating equipment is usually placed on one side of transportation systems as this is considered to be more practical. Such a configuration thus leads to significant temperature differences in the two distinct parts of a refrigerated cargo trailer, which might affect the quality, safety, and shelf life of perishable foods. This research aims to improve the temperature distribution of refrigerated trailers. In this study, it is highlighted that in the most commonly used traditional refrigerated trailer models, lower air velocity and higher product temperature are observed at the rear. There is also a partial product chilling risk at the front of the refrigerated trailer. This study investigates and reports significant differences among the three airflow design models of refrigerated cargo systems by applying turbulence flow, heat, and mass transfer models. The analyses of these three models reveal that significant improvement could be achieved by applying the proper arrangements of inlets on the ceiling of the trailer body. © 2019 by the author.Article Citation - WoS: 11Citation - Scopus: 17Design and Analysis of a Lightweight Composite Shipping Container Made of Carbon Fiber Laminates(MDPI, 2019) Yildiz,T.The literature indicates that a 20% reduction in the weight of empty 40-foot shipping containers would result in $28 billion of fuel savings, along with a 3.6 exajoule reduction in the energy demand over containers’ 15-year lifetime. Decreasing the energy demand and thereby greenhouse gas emissions by utilizing lightweight shipping containers has been an unexplored strategy. In this regard, this study investigates the possibility of further reducing the weight of an empty container without compromising the structural integrity, strength, and function of a traditional steel container. This research finds that up to an 80% reduction in weight is possible by producing shipping containers with composite materials. This research presents the new design of a 40-foot container made of carbon fiber laminates. The tare weight of a traditional 40-foot shipping container is around 3750 kg. On the contrary, in this research, the weight of a composite design of the same container is calculated to be around 822 kg. Additional tests with various loads, such as lifting the container and stacking loads onto the composite container, are performed to explore the strength and buckling issues of the design presented in this study. The analyses reveal that the composite shipping container is a highly promising candidate for reducing greenhouse gas emissions, providing fuel savings and thus reducing the operational costs of transportation. © 2019 by the author.Article Citation - WoS: 3Citation - Scopus: 4Evaluation of Multifunctional Hybrid Analogs for Stilbenes, Chalcones and Flavanones(Bentham Science Publishers, 2017) Çağır, Ali; Odacı, Burcu; Varol, Mehmet; Akçok, İsmail; Okur, Özgür; Koparal, Ayşe T.Aims: In this study, discovery of novel anticancer agents acting by more than one mechanism was aimed. Method: For this purpose, eleven previously synthesized simple-stilbene, chalcone, flavanone derivatives and 31 novel stilbene-fused chalcones and stilbene-fused flavanones were tested for their aromatase inhibition, anti-angiogenic and anti-proliferative properties in cancer (PC3, MCF-7) and healthy (HUVEC) cell lines. MTT cell viability assay was used to evaluate the anti-proliferative activities of the compounds. CYP19/MFC high-throughput screening kit (BD Biosciences, Oxford, UK) was used to search the aromatase inhibition properties and matrigel tube formation assay was applied to determine the anti-angiogenic activities. Results: Results indicate that the simple-chalcone and flavanone derivatives were more cytotoxic than the simple-stilbenes in the both cancer cell lines. In contrast, the simple-stilbene structures were much more effective at aromatase inhibition. The cytotoxicity profiles of stilbene-fused chalcones in cancer cells imply that these molecules mostly mimic the simple chalcone structures. On the other hand, flavanones lose their cytotoxic activities after becoming fused with stilbenes. Additionally, aromatase inhibition assays showed that stilbene-fused chalcones again do mimic the simple-chalcones but not simple-stilbenes and anti-angiogenic profiles of the tested molecules seem to be not related with stilbene fragments. Furthermore, stilbene-fused flavanones may mimic both simple-flavanones and simple-stilbenes depending upon the type and position of the substituent in their respective terminal aromatic rings.Article Citation - WoS: 32Citation - Scopus: 30Geochemical and Hydrogeochemical Characteristics and Evolution of Kozaklı Geothermal Fluids, Central Anatolia, Turkey(Elsevier Ltd., 2019) Baba, Alper; Şener, Mehmet FurkanKozaklı is one of the most important areas of Central Anatolia in terms of geothermal potential and it is characterized by thrust and normal faults. These faults, accommodating deep circulation of hydrothermal fluids of meteoric origin, are the primary controls of the geothermal systems in this region. Chemical and isotopic composition of the hot springs and geothermal fluids was monitored throughout 2017. The surface temperature of the fluid ranges from 24.9 to 96 °C. The cold spring waters are mostly of the Ca-Mg−HCO3 type in the study area. Major element chemistry of the water reveals that the deep geothermal fluids are mostly of the Na-Ca-Cl-SO4 type while the shallow geothermal well waters are Ca-Na−HCO3 waters. Silica geothermometers suggest that the reservoir temperature ranges from 103 to 173 °C. Based on the δ18O–δD relationship, water samples have a high-altitude meteoric origin. Stable isotopic data indicate that the geothermal fluids are formed by local recharge and deep circulation of meteoric waters. The Rare Earth Elements and Yttrium (REY) composition showed that Eu, Ce and Y anomalies are related both to inheritance from geological host materials and the fractionation of these elements during water-rock interactions.Article Citation - WoS: 1Effect of Ultraviolet B Radiation on the Absorption Characteristics of Various Intraocular Lenses(S. Karger AG, 2006) Koçak, Nilüfer; Kaynak, Süleyman; İlknur, Turna; Özkan, Şebnem; Erdoğan, Gökhan; Çıngıl, GürayBackground: The aim of this study was to determine the effect of ultraviolet B (UVB) exposure on UV filters of various intraocular lenses (IOLs). Methods: Eight samples each of the hydrophobic acrylic, hydrophilic acrylic and silicone IOLs were used. Four IOLs of each type was selected randomly as the control group while the remaining four IOLs of each type were exposed to a UVB dose of 1.4 J/cm2 (2.40 mW/cm2) for 9.45 min, two times with a 4-week interval. IOLs were evaluated for any sign of opacification under microscope weekly. After a follow-up period of 16 weeks, spectrometry for UV filter absorption rates, scanning electron microscopy for deposit formation and energy dispersive X-ray analysis for elemental composition were performed for all IOLs, and findings of the control group IOLs were compared with those of the UVB-exposed IOLs. All these procedures were done at the Department of Ophthalmology, Faculty of Medicine, Dokuz Eylul University. Results: All the IOLs were free of any opacification during the follow-up period. Spectrometric analysis of their UV filters revealed a change in absorption rates in the hydrophilic acrylic and silicone IOLs compared to the control IOLs of the same type. Only the hydrophobic acrylic IOLs preserved the same UV absorption curve after UVB exposure. Conclusion: The pathogenesis of IOL opacification is still undetermined. Some reports claimed that the UV light was the responsible factor. Our experimental study revealed that high doses of UVB did not cause any opacification though they impaired the function of UV filters of the hydrophilic acrylic and silicone IOLs. Copyright © 2007 S. Karger AG.Article Citation - Scopus: 9An Empirical Analysis on Logistics Performance and the Global Competitiveness(Vilnius Gedminas Technical University, 2017) Yıldız, TürkayLogistics has been identified as an area to build cost and service advantages. Therefore, companies are more focused on customer needs and trying to find ways to reduce costs, improve quality and meet the growing expectations of their clients. Indeed, the global competition has led managers to begin to address the issue of providing more efficient logistics services. In this regard, this paper presents an empirical study on logistics performance and global competitiveness. This paper also identifies the associations between logistics performances and global competitiveness. The results indicate that some variables in global competitiveness scores contribute much higher to the logistics performances than the other variables through analysis. The variables that contribute much higher than the other variables to the logistics performances are shown.Article Citation - Scopus: 2The European Union and Turkey: a Review of Their Commonalities and Disparities Using Cluster Analysis(Vilnius Gediminas Technical University, 2014) Yıldız, TürkayTurkey has enjoyed considerable economic growth over the past decade and has a positive economic outlook and strong growth prospects. The country benefits from being located between Europe and the major energy producers in the Middle East in the so-called strategic energy corridor. The issue of Turkey's accession to the EU has long been on the political agenda in Europe. Indeed, Turkey has made considerable efforts to become a full EU member state. However, the accession negotiations for EU membership continue, while Turkey has recently refused to open new accession chapters with the EU and instead has turned its attention to other regional developments. Turkey has strengthened its swtrategic ties with a wide range of countries including those in Europe and the Middle East. It also plays an influential role in a geography that stretches across the former Soviet Union nations. In this paper, the path of Turkey's accession issues is reviewed and the direction of its economy based on the measure of GDP per capita is forecast using an autoregressive integrated moving average model. In addition, the cluster analysis technique is adopted in order to measure the possible standing of Turkey among EU members, the similarities between EU members, and the current path to becoming an EU member state.Article Citation - WoS: 3Citation - Scopus: 3Effects of Different Lipopolysaccharide Preparations on Neutrophil Function in the Fathead Minnow, Pimephales Promelas Rafinesque(John Wiley and Sons Inc., 2011) Jovanovic, B.; Baran, Ezgi; Goetz, F. W.; Palic, D.The fish innate immune response to pathogensrelies on the adequate function of neu trophilicgranulocytes (Palic´, Andreasen, Herolt, Menzel &Roth 2006). The ability of neutrophils to phago-cytose microor ganisms and cellular debris is essen-tial for normal development an d survival of animalpopulations (Segal 2005). The evaluation of neu-trophil function is valuable for assessing the healthstatus of individuals and fish populations (Smith &Lumsden 1983). Resistance of fishes to septic shockand tolerance to high concentrations of lipopoly-saccharide (LPS) was observed as a major differencebetween mammalian and fish innate immuneresponses (Berczi, Bertok & Bereznai 1966). Thisfunctional difference could be attri buted to severalcostimulatory molecules and intracellular mediatorsbeing absent in fish, but active in mammals duringresponse to LPS stimulation (Iliev, Roach, Mac-kenzie, Planas & Goetz 2005). Most fish do notpossess a Toll-like receptor (TLR) with sequencesimilarity to mammalian TLR4 (Leulier & Lemai-tre 2008) and the ones that do have no ability forTLR4 downstream signalling (Sepulcre, Alcaraz-Perez, Lopez-Munoz, Roca, Meseguer, Cayuela &Mulero 2009). Regardless of the absence andfunctionality of TLR4 and costimulatory molecules,bacterial LPS can induce a robus t inflammatorygene response in innate immune fish cells, but atconcentrations 1000-fold higher than is commonlyobserved in mammalian species ( lgmL)1vs.ng mL)1) (Palic´, Ostojic, Andreasen & Roth2007; Mackenzie, Roher, Boltan˜a & Goetz 2010).In contrast, ultrapure LPS preparations are rela-tively inactive in fish (Iliev et al. 2005).Article Citation - WoS: 27Citation - Scopus: 28An Exergetic Performance Assessment of Three Different Food Driers(SAGE Publications Inc., 2010) Hepbaşlı, Arif; Erbay, Zafer; Çolak, Neslihan; Hancıoğlu, Ebru; İçier, FilizIn this study, plum slices were dried in three different driers (tray, fluid bed, and heat pump (HP) driers). Drying experiments were carried out at an air temperature range of 45-55 °C with an air velocity of 1.5 m/s. The performance of the driers along with their main components was evaluated and compared by using the exergy analysis method. The most important component for improving the system efficiency was determined to be the fan-heater combination for both the tray and fluid bed driers, and the motor-compressor assembly for the HP drier. The exergy loss and flow diagram (the so-called Grassmann diagram) of the driers was also presented to give quantitative information regarding the proportion of the exergy input dissipated in the various system components. Effects of the drying air temperature on the performance of the drying process were discussed. The highest exergetic efficiency values were obtained to range from 72.72 to 75.66 per cent for the HP drier, followed by the tray and fluid bed driers varying between 37.94 and 39.46 per cent, and between 22.83 and 24.07 per cent, respectively.Article Citation - WoS: 71Citation - Scopus: 77A Comparative Study on Exergetic Performance Assessment for Drying of Broccoli Florets in Three Different Drying Systems(Taylor and Francis Ltd., 2010) İçier, Filiz; Çolak, Neslihan; Erbay, Zafer; Hancıoğlu Kuzgunkaya, Ebru; Hepbaşlı, ArifThis article deals with the exergy analysis and evaluation of broccoli in three different drying systems. The effects of drying air temperature on the exergy destruction, exergy efficiency, and exergetic improvement potential of the drying process were investigated. The exergy destruction rate for the drying chamber increased with the rise in the drying air temperature at 1.5 m/s, both in the tray and the heat pump dryer. The highest exergy efficiency value was obtained as 90.86% in the fluid bed dryer in comparison to the other two drying systems and the improvement potential rate was the highest in the heat pump dryer during drying of broccoli at the drying air temperature of 45°C and the drying air velocity of 1.0 m/s. © 2010 Taylor & Francis Group, LLC.