Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
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Article Citation - WoS: 4Citation - Scopus: 4Zn/Na Co-Doped Hydroxyapatites: Synthesis, Antibacterial, and Bioactivity Studies(Elsevier Science Sa, 2025) Samadi, Hamed; Pakchin, Parvin Samadi; Mohammadpourfard, Mousa; Adibkia, KhosroThe most crucial challenge of post-orthopedic surgery is related to bacterial film formation, which leads to implant failure. In this work, zinc/sodium (Zn/Na) co-doped hydroxyapatite nanoparticles (HA NPs) with different Zn/Na concentrations, including 1, 3, and 5 mol.% were synthesized using a hydrothermal method. Several analyses such as X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Energy Dispersive X-ray Spectroscopy (EDX), Scanning Electron Microscopy (SEM), and N2 ad/desorption were used to pinpoint the properties of as-prepared materials. Field Emission Scanning Electron Microscopy (FE-SEM) and EDX analysis demonstrated that the HA NPs possess an average size of about 30-40 nm and hexagonal morphology with no impurity. XRD patterns confirm that by the increasing amounts of Zn/Na, the crystal size of samples was decreased. FT-IR affirms the correct doping of metal ions. Brunauer-Emmett-Teller (BET) results of co-doped samples demonstrated a microporous structure, which can improve fluid flow in the inner structure of implants. The colony-forming unit (CFU) method conducted the antibacterial test, which confirmed that 5 mol.% Zn/Na co-doped HA NPs showed the highest antibacterial properties against Escherichia coli (PTCC 1276) (E. coli). Cytotoxicity results affirmed that 1 and 3mol.% Zn/Na co-doped HA NPs demonstrated low toxicity. Bioactivity tests revealed that the Zn/Na co-doped samples showed a higher ability to facilitate bone marrow stem cells; thus, improving the proliferation after the immersion in simulated body fluid (SBF). Therefore, Zn/Na co-doped HA NPs could be a promising candidate for bone tissue engineering applications.Review Citation - WoS: 14Citation - Scopus: 16Advancing Titanium-Based Surfaces Via Micro-Arc Oxidation With Solid Substance Incorporation: a Systematic Review(Elsevier, 2024) Ogur, Ezgi; Alves, Alexandra C.; Toptan, FatihDespite possessing numerous superior properties, titanium, and its alloys exhibit inadequacies in terms of tribocorrosion, bioactivity, and antimicrobial characteristics. In recent years, there has been a rapid increase in research focusing on micro-arc oxidation (MAO) surface treatments to enhance these properties. In the traditional MAO approach, researchers commonly investigate the introduction of additional functionalities to the surface through ion doping. However, over the past decade, studies have indicated that the inclusion of solid substances, either as substitutes for or in conjunction with ion doping, can provide further advantages in terms of multifunctionality. Therefore, this review comprehensively and systematically examines the characteristics of solid substances used during MAO, their incorporation mechanisms, and their influence on resulting biological and degradation behaviors, as well as properties such as photocatalytic activity, magnetic features, hightemperature oxidation resistance, electrical insulation, and thermal shock resistance. This review showed that the integration of solid substances during MAO represents a promising avenue for achieving multifunctional surface enhancements in titanium and its alloys. This review highlights the diverse range of properties and behaviors influenced by these solid substances, offering insights for future research and applications in the field of surface engineering and biomaterials science.