Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
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Article Nanoencapsulation of Hydroxytyrosol Extract of Fermented Olive Leaf Brine Using Proniosomes(Wiley, 2025) Kadiroglu, Pinar; Kilincli, Betul; Ilgaz, Ceren; Bayindir, Zerrin Sezgin; Kelebek, Hasim; Helvacioglu, Selin; Ozhan, GunesBACKGROUND: Olive leaves are rich in bioactive compounds with potential health benefits; however, their limited bioavailability and stability hinder their effective utilization. Emerging technologies, nanocarrier-based delivery systems, have shown promise in enhancing these properties. RESULTS: The optimal conditions for proniosome formulation were 50 rpm rotational speed and 35 degrees C, achieving 81.20 +/- 0.80% encapsulation efficiency. Particle sizes ranged from 188.6 to 248.9 nm, with a zeta potential of similar to-30 mV, indicating high stability and resistance to aggregation. Advanced instrumental analysis confirmed interactions between the extract and proniosome components. After 30 days at 4 degrees C, extract-loaded proniosomes maintained better homogeneity and lower polydispersity index. Cytotoxicity studies showed that both the extract and its proniosomal form were nontoxic to HEK293T cells up to 200 mu g mL(-1). In zebrafish assays, minimal larval mortality was observed up to 3200 mu g mL(-1) for the extract, while no mortality occurred up to 1600 mu g mL(-1) for the proniosomal extract, highlighting its improved safety profile. CONCLUSION: The findings from this research could contribute to the advancement of sustainable and health-promoting food innovations by integrating cutting-edge nanotechnology-driven encapsulation strategies into plant-based food formulations. (c) 2025 Society of Chemical Industry.Conference Object Citation - WoS: 1Citation - Scopus: 1Microstructural Evolution During Homogenization Heat Treatment of Aa 6063 Alloy in Batch and Continuous Furnaces(Springer international Publishing Ag, 2024) Obali, Akin; Gokelma, Mertol; Urk, Deniz Kavrar; Dogan, Murat; Gokce, GokcenHomogenization heat treatment after casting is performed to eliminate the dendritic segregation and coarse eutectic intermetallic phases since they reduce the fracture toughness of aluminium alloys. By the homogenization treatment, ss-AlFeSi can be converted to more spherical alpha-AlFeSi particles. The ss -> a transition is crucial because the ss-AlFeSi particles cause a number of surface defects and limit the extrudability. Also, the rate of cooling in the homogenization furnace is one of the critical influencing factors on the size of the Mg2Si precipitates which affect the mechanical properties positively. In this study, billets of AA 6063 from the same cast were put through homogenization heat treatment by using batch-type and continuous furnaces. The solution, quenching, and aging heat treatment were applied to each sample. Microstructural characterization by SEM and the hardness test were conducted to understand the effects of the furnace type on the mechanical properties of aged AA 6063 aluminium.Article Citation - Scopus: 1Characteristics and Production Technologies of Byzantine Building Bricks From the Anaia Church in Western Anatolia(Springer, 2023) Çam, Elif; Uğurlu Sağın, ElifFired bricks were valued as essential building materials in the central tradition of Byzantine architecture in Constantinople (Istanbul), Anatolia, and the Balkans. In this study, Byzantine bricks from three construction periods, covering nearly nine centuries (fifth-fourteenth centuries), of Anaia Church (Kadikalesi) in Western Anatolia were investigated to determine their characteristics, raw material properties, and production technologies. The characteristics of the bricks were evaluated and compared in order to identify similarities and differences between the periods and to investigate the continuity of the tradition of brick production over centuries. Basic physical and colorimetric properties, chemical and mineralogical compositions, thermal behavior, and microstructural and mechanical properties of bricks were determined by scanning electron microscopy (SEM) coupled with energy dispersive spectroscopy (SEM-EDS), Fourier-transform infrared spectrometry (FTIR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), and mechanical tests. The results indicated that all the bricks in the Anaia Church were brown-beige colored, highly porous, low-density materials with low mechanical strength. They were produced from Ca-rich clays, probably obtained from two different sources used during all construction periods. The mineralogical composition and thermal properties revealed that the bricks from the first and second periods were fired at between 800 and 900 & DEG;C and the bricks from the third period were fired at < 850 & DEG;C. Greater calcium content and firing temperatures were found to reduce the total porosity and the number of small pores (< 10 & mu;m) and increase the mechanical strength of the bricks. The results of the study revealed no significant differences in the production of bricks, including raw material sources and kiln conditions, for the different construction periods of the church.