Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/11147/7148

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Access type: Open accessPublisher: search.filters.publisher.Hindawi Publishing Corporation

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  • Article
    Fine-Tuned Spin-3/2 and the Hierarchy Problem
    (Hindawi Publishing Corporation, 2020) Sargın, Ozan
    In the past, Kundu et al. and Chakraborty et al. used extra scalar fields to cancel the quadratic divergences in the Higgs mass squared and they determined the mass of the required scalar field. In this work, a spin-3/2 particle has been used in the same manner to nullify the power-law divergences, and it is determined that the mass of the spin-3/2 particle resides in the ball park of the GUT scale.
  • Article
    Citation - WoS: 4
    Citation - Scopus: 6
    Testing the Performance of Various Polymeric Antiscalants for Mitigation of Sb-Rich Precipitates Mimicking Stibnite-Based Geothermal Deposits
    (Hindawi Publishing Corporation, 2020) Çiftçi, Celal; Karaburun, Emre; Tonkul, Serhat; Baba, Alper; Demir, Mustafa Muammer; Yeşilnacar, Mehmet İrfan
    Scaling is frequently observed in geothermal fields and reduces the energy harvesting of power plants. Recently, Sb-rich deposits have developed in many fields around the world. Various polymeric macromolecules have been used as antiscalants to mitigate the formation of scale. Testing potential commercial antiscalants in field conditions is a tedious and costly process. The artificial synthesis of geothermal deposits in the lab is a more practical and economical way to test the performance of antiscalants. This study obtained a Sb-rich deposit by refluxing SbCl3 and Na2S center dot 3H(2)O in 18 h. The product was found to be a mixture of Sb2O3 and Sb2S3. We examined the performance of antiscalants such as poly(ethylene glycol), poly(vinyl pyrrolidone), Gelatin, and poly(vinyl alcohol) of various molecular weights at 5 to 100 ppm. The formation of Sb2S3 is suppressed in the presence of the polymeric antiscalants. The dosage was found to be critical for the solubilization of Sb-rich deposits. Gelatin of 5 ppm showed the highest performance under the conditions employed in this study. While low dosages improve the concentration of [Sb3+], high dosages are required to increase the solubility of [S2-]. Moreover, the amount of deposit is reduced by 12.4% compared to the reference (in the absence of any polymeric molecules). Thus, comparatively, Gelatin shows the most promising performance among the molecules employed.
  • Article
    Citation - WoS: 33
    Citation - Scopus: 34
    Effects of N-Terminal and C-Terminal Polyhistidine Tag on the Stability and Function of the Thermophilic P450 Cyp119
    (Hindawi Publishing Corporation, 2019) Aslantaş, Yaprak; Sürmeli, Nur Başak
    Biocatalysts are sought-after in synthesis of pharmaceuticals and agrochemicals due to their high regioselectivity and enantioselectivity. Among biocatalysts, heme-containing cytochrome P450 (P450) oxygenases are an attractive target since they catalyze oxidation of "unactivated" carbon-hydrogen bonds with high efficiency. CYP119 is an acidothermophilic P450 from Sulfolobus acidocaldarius, which has the potential to be widely used as a biocatalyst since it shows activity at high temperatures and low pH. Polyhistidine tags (His-tags) are widely used to simplify purification of proteins. However, His-tags can cause changes to protein structure and function. Here, we demonstrate the effects of His-tags on CYP119. To this end, the His-tags were cloned at the N-terminus or C-terminus of the CYP119, and His-tagged proteins were expressed and isolated. The thermostability and peroxidase activity of His-tagged CYP119s were tested and compared to wild type CYP119. Results indicated that while addition of His-tags increased the yield and simplified isolation of CYP119, they also influenced the electronic structure of active site and the activity of the protein. We show that N-terminal His-tagged CYP119 has desirable properties and potential to be used in industrial applications, but mechanistic studies using this protein need careful interpretation since the His-tag affects electronic properties of the active site heme iron.
  • Article
    Citation - WoS: 25
    Citation - Scopus: 27
    Symmergent Gravity, Seesawic New Physics, and Their Experimental Signatures
    (Hindawi Publishing Corporation, 2019) Demir, Durmuş Ali
    The standard model of elementary particles (SM) suffers from various problems, such as power-law ultraviolet (UV) sensitivity, exclusion of general relativity (GR), and absence of a dark matter candidate. The LHC experiments, according to which the TeV domain appears to be empty of new particles, started sidelining TeV-scale SUSY and other known cures of the UV sensitivity. In search for a remedy, in this work, it is revealed that affine curvature can emerge in a way restoring gauge symmetries explicitly broken by the UV cutoff. This emergent curvature cures the UV sensitivity and incorporates GR as symmetry-restoring emergent gravity (symmergent gravity, in brief) if a new physics sector (NP) exists to generate the Planck scale and if SM+NP is Fermi-Bose balanced. This setup, carrying fingerprints of trans-Planckian SUSY, predicts that gravity is Einstein (no higher-curvature terms), cosmic/gamma rays can originate from heavy NP scalars, and the UV cutoff might take right value to suppress the cosmological constant (alleviating fine-tuning with SUSY). The NP does not have to couple to the SM. In fact, NP-SM coupling can take any value from zero to Lambda SM2/Lambda NP2 if the SM is not to jump from Lambda SM approximate to 500GeV to the NP scale Lambda NP. The zero coupling, certifying an undetectable NP, agrees with all the collider and dark matter bounds at present. The seesawic bound Lambda SM2/Lambda NP2, directly verifiable at colliders, implies that (i) dark matter must have a mass less than or similar to Lambda SM, (ii) Higgs-curvature coupling must be approximate to 1.3%, (iii) the SM RGEs must remain nearly as in the SM, and (iv) right-handed neutrinos must have a mass less than or similar to 1000TeV. These signatures serve as a concise testbed for symmergence.
  • Editorial
    Citation - Scopus: 1
    Novel Methodologies for Food Quality and Provenance Fingerprints Assessment
    (Hindawi Publishing Corporation, 2019) Ceto, Xavier; Diaz-Cruz, Jose M.; Tokatlı, Figen; Lucci, Paolo; Moret, Sabrina
    The development of novel reliable methodologies that allow the control, assessment, and prediction of the characteristics of food products is a field under expansion nowadays, especially those that allow their characterization, classification, and authentication. On the one side, the highly competitive global environment in food industry requires continuous innovation and a better sustainable usage of our natural resources in order to improve the high standards of food producers, leading to high value-added products. The linkage of new research ideas with food production provides a competitive advantage to food makers to fulfil the competitive market challenges.
  • Article
    Citation - WoS: 14
    Citation - Scopus: 18
    Comparison of Antimicrobial Activity of Allium Sativum Cloves From China and Taskopru, Turkey
    (Hindawi Publishing Corporation, 2018) Yetgin, Ali; Canlı, Kerem; Altuner, Ergin Murat
    In this study, antimicrobial activities of two different samples of Allium sativum L. from Turkey (TR) (Taskopru, Kastamonu, Turkey) and China (CN) were determined. A broad spectrum of Gram-negative and Gram-positive bacteria (17 bacteria) including species of Bacillus, Enterobacter, Enterococcus, Escherichia, Klebsiella, Listeria, Pseudomonas, Salmonella, and Staphylococcus were used for testing antibacterial activity. In addition, antifungal activity against Candida albicans was also investigated. Antimicrobial activity was tested by using 3 different processes (chopping, freezing, and slicing by the disk diffusion method). The results showed that TR garlic presented more antimicrobial activity than CN garlic. Mechanism of activity of CN garlic could be proposed to be different from that of TR garlic.
  • Article
    Citation - WoS: 22
    Citation - Scopus: 26
    In Vitro Antimicrobial Activity Screening of Ethanol Extract of Lavandula Stoechas and Investigation of Its Biochemical Composition
    (Hindawi Publishing Corporation, 2019) Canlı, Kerem; Yetgin, Ali; Benek, Atakan; Bozyel, Mustafa Eray; Altuner, Ergin Murat
    The aim of this study was to test antimicrobial activity of ethanol extract of Lavandula stoechas against 22 bacteria and 1 yeast. Also, biochemical composition of the extract was investigated. A wide range of Gram-positive, Gram-negative microorganisms, and multidrug resistant bacteria were selected to test the antimicrobial activity. As a result, the extract is observed to contain fenchone (bicyclo[2.2.1]heptan-2-one, 1,3,3-trimethyl-, (1R)-) and camphor (+)-2-bornanone) as major components and showed antimicrobial activity against all studied microorganisms except Escherichia coli ATCC 25922 and Klebsiella pneumoniae. The results of the study present that L. stoechas is active against MDR strains too.
  • Article
    Citation - WoS: 10
    Citation - Scopus: 26
    Mobile Join Operators for Restricted Sources
    (Hindawi Publishing Corporation, 2005) Özakar, Belgin; Morvan, Franck; Hameurlain, Abdelkader
    We consider the problem of query execution when there is limited access to the relations, i.e. when binding patterns require values to be specified in order to get data from the relation. This problem is common in virtual data integration systems where there are heterogeneous sources with various restricted access patterns and query capabilities. Another problem is the lack of the statistical information about the sources and occurrence of unpredictable events. We introduce two mobile join operators, MDJoin and SMDJoin which are designed for restricted sources and implemented using ‘mobile agents’ in order to benefit from their autonomous and reactive characteristics. Mobile operators of restricted sources are capable to deal with restricted sources and react to the variations between the compile-time estimations and run-time computations of data during query execution. The difference between the two new query operators lies in their level of adaptation ability to the execution environment. Performance results show that mobile agent-based approach at operator level can lead to a significant reduction in response time with restricted sources.
  • Article
    Citation - WoS: 11
    Citation - Scopus: 11
    Mice With Catalytically Inactive Cathepsin a Display Neurobehavioral Alterations
    (Hindawi Publishing Corporation, 2017) Çalhan, Osman Yipkin; Seyrantepe, Volkan
    The lysosomal carboxypeptidase A, Cathepsin A (CathA), is a serine protease with two distinct functions. CathA protects β-galactosidase and sialidase Neu1 against proteolytic degradation by forming a multienzyme complex and activates sialidase Neu1. CathA deficiency causes the lysosomal storage disease, galactosialidosis. These patients present with a broad range of clinical phenotypes, including growth retardation, and neurological deterioration along with the accumulation of the vasoactive peptide, endothelin-1, in the brain. Previous in vitro studies have shown that CathA has specific activity against vasoactive peptides and neuropeptides, including endothelin-1 and oxytocin. A mutant mouse with catalytically inactive CathA enzyme (CathAS190A) shows increased levels of endothelin-1. In the present study, we elucidated the involvement of CathA in learning and long-term memory in 3-, 6-, and 12-month-old mice. Hippocampal endothelin-1 and oxytocin accumulated in CathAS190A mice, which showed learning impairments as well as long-term and spatial memory deficits compared with wild-type littermates, suggesting that CathA plays a significant role in learning and in memory consolidation through its regulatory role in vasoactive peptide processing.
  • Article
    Citation - WoS: 12
    Citation - Scopus: 14
    Zinc Electrode Morphology Evolution in High Energy Density Nickel-Zinc Batteries
    (Hindawi Publishing Corporation, 2016) Payer, Gizem; Ebil, Özgenç
    Prismatic Nickel-Zinc (NiZn) batteries with energy densities higher than 100 Wh kg-1 were prepared using Zn electrodes with different initial morphologies. The effect of initial morphology of zinc electrode on battery capacity was investigated. Scanning electron microscopy (SEM) and X-ray diffraction (XRD) reveal that initial morphology of zinc electrode changes drastically after a few charge/discharge cycles regardless of initial ZnO powder used. ZnO electrodes prepared using ZnO powders synthesized from ZnCl2 and Zn(NO3)2 lead to average battery energy densities ranging between 92 Wh kg-1 and 109 Wh kg-1 while using conventional ZnO powder leads to a higher energy density, 118 Wh kg-1. Average discharge capacities of zinc electrodes vary between 270 and 345 mA g-1, much lower than reported values for nano ZnO powders in literature. Higher electrode surface area or higher electrode discharge capacity does not necessarily translate to higher battery energy density.