Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/11147/7148

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Access type: Open accessSubject: search.filters.subject.Hybridization

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  • Article
    Citation - WoS: 40
    Citation - Scopus: 37
    Investigation of Interlayer Hybridization Effect on Burst Pressure Performance of Composite Overwrapped Pressure Vessels With Load-Sharing Metallic Liner
    (SAGE Publications, 2020) Kangal, Serkan; Kartav, Osman; Tanoğlu, Metin; Aktaş, Engin; Artem, Hatice Seçil
    In this study, multi-layered composite overwrapped pressure vessels for high-pressure gaseous storage were designed, modeled by finite element method and manufactured by filament winding technique. 34CrMo4 steel was selected as a load-sharing metallic liner. Glass and carbon filaments were overwrapped on the liner with a winding angle of [+/- 11 degrees/90 degrees(2)](3) to obtain fully overwrapped composite reinforced vessel with non-identical front and back dome endings. The vessels were loaded with increasing internal pressure up to the burst pressure level. The mechanical performances of pressure vessels, (i) fully overwrapped with glass fibers and (ii) with additional two carbon hoop layers on the cylindrical section, were investigated by both experimental and numerical approaches. In numerical approaches, finite element analysis was performed featuring a simple progressive damage model available in ANSYS software package for the composite section. The metal liner was modeled as elastic-plastic material. The results reveal that the finite element model provides a good correlation between experimental and numerical strain results for the vessels, together with the indication of the positive effect on radial deformation of the COPVs due to the composite interlayer hybridization. The constructed model was also able to predict experimental burst pressures within a range of 8%. However, the experimental and finite element analysis results showed that hybridization of hoop layers did not have any significant impact on the burst pressure performance of the vessels. This finding was attributed to the change of load-sharing capacity of composite layers due to the stiffness difference of carbon and glass fibers.
  • Article
    Citation - WoS: 12
    Citation - Scopus: 14
    Thermodynamically Designed Target-Specific Dna Probe as an Electrochemical Hybridization Biosensor
    (Elsevier Ltd., 2020) Can, Faruk; Ökten, Hatice Eser; Ergön Can, Tülay; Ergenekon, Pınar; Özkan, Melek; Erhan, Elif
    Applications of molecular techniques to elucidate identity or function using biomarkers still remain highly empirical and biosensors are no exception. In the present study, target-specific oligonucleotide probes for E. coli K12 were designed thermodynamically and applied in an electrochemical DNA biosensor setup. Biosensor was prepared by immobilization of a stem–loop structured probe, modified with a thiol functional group at its 5′ end and a biotin molecule at its 3′ end, on a gold electrode through self-assembly. Mercaptopropionic acid (MPA) was used to optimize the surface probe density of the electrode. Hybridization between the immobilized probe and the target DNA was detected via the electrochemical response of streptavidin-horseradish peroxidase in the presence of the substrate. The amperometric response showed a linear relationship with the target DNA concentration, ranging from 10 and 400 nM, with a correlation coefficient of 0.989. High selectivity and good repeatability of the biosensor showed that the thermodynamic approach to oligonucleotide probe design can be used in development of electrochemical DNA biosensors.