Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
Browse
4 results
Search Results
Article Citation - WoS: 8Citation - Scopus: 9Polymeric Thermal Analysis of C+h and C+h+ar Ion Implanted Uhmwpe Samples(Elsevier Ltd., 2007) Kaya, N.; Öztarhan, Ahmet M.; Urkaç, Emel Sokullu; Ila, D.; Budak, S.; Oks, E.; Tıhmınlıoğlu, Funda; Muntele, C.Chemical surface characterization of C + H hybrid ion implanted UHMWPE samples were carried out using DSC (differential scanning calorimeter) and TGA (thermal gravimetric analysis) techniques. Samples were implanted with a fluence of 10(17) ion/cm(2) and an extraction voltage of 30 kV. The study of TGA and DSC curves showed that: (1) Polymeric decomposition temperature increased, (2) T-m, Delta C-p and Delta H-m values changed while Delta C-p and Delta H-m increased. T-g value could not be measured, because of some experimental limitations. However, the increase in Delta H-m values showed that T-g values increased, (3) the branch density which indicated the increase in number of cross-link (M-c) decreased in ion implanted samples and (4) increase in Delta H-m values indicated increase in crystallinity of implanted surface of UHMWPE samples.Article Citation - WoS: 25Citation - Scopus: 33Novel Phytochemical Cissus Quadrangularis Extract-Loaded Chitosan/Na-carboxymethyl Cellulose-Based Scaffolds for Bone Regeneration(SAGE Publications, 2018) Tamburacı, Sedef; Kimna, Ceren; Tıhmınlıoğlu, FundaMedicinal plants are attracting considerable interest as a potential therapeutic agent for bone tissue regeneration. Cissus quadrangularis L. is also a medicinal plant known with its osteogenic activity. In this study, a phytochemical scaffold was produced by incorporating Cissus quadrangularis with chitosan/Na-carboxymethyl cellulose blend by lyophilization technique. The effect of Cissus quadrangularis loading on the mechanical, morphological, chemical, and degradation properties as well as in vitro cytotoxicity, cell proliferation, and differentiation of the composites was investigated. Scanning electron microscopy images showed that porous Cissus quadrangularis-loaded scaffolds were obtained with an average pore size of 148-209 mu m which is appropriate for bone regeneration. Cissus quadrangularis incorporation enhanced the compression modulus of scaffolds from 76 to 654 kPa. In vitro cell culture results indicated that Cissus quadrangularis/chitosan/Na-carboxymethyl cellulose scaffolds provided a favorable substrate for the osteoblast adhesion, proliferation, and mineralization. Results supported the osteoinductive property of the Cissus quadrangularis extract-incorporated scaffolds even without osteogenic media supplement. Cissus quadrangularis extract increased the alkaline phosphatase activity of the SaOS-2 cells on scaffolds on 7th and 14th days of incubation. The investigation of characterization and cell culture studies suggest that Cissus quadrangularis-loaded osteoinductive Cissus quadrangularis/chitosan/Na-carboxymethyl cellulose scaffold can serve as a potential biomaterial for bone tissue engineering applications.Article Citation - WoS: 9Citation - Scopus: 11Oxidation Behavior of C-And Au-Ion Biodegradable Polymers(Institute of Electrical and Electronics Engineers Inc., 2012) Sokullu Urkaç, Emel; Öztarhan, Ahmet; Tıhmınlıoğlu, Funda; Nikolaev, Alexey; Brown, IanBiodegradable polymers are widely used in biomedical and tissue engineering applications due to their biocompatibility and hydrolysis properties in the body. However, their low surface energy and lack of functional groups to interact with the cellular environment have limited their applications for in vivo studies. Ion beam modification is a convenient method for improving the surface properties of polymeric materials for functional biomedical applications. In the work described here, vacuum arc metal ion implantation was used to modify the composition of the near-surface region of three kinds of polymerspoly(L-lactide), poly(D, L-lactide-co-glycolide), and poly(L-lactide/caprolactone)chosen as representative of biodegradable polymers. X-ray photoelectron spectroscopy analysis was used to characterize the chemical effects of these polymers after implantation with C and with Au, and the results were compared with untreated control samples. We find that oxidation behavior is brought about for certain implantation fluences, resulting in improved surface hydrophilicity. © 2011 IEEE.Article Citation - WoS: 10Citation - Scopus: 11Use of Clinoptilolite in Ethanol Dehydration(Taylor and Francis Ltd., 1996) Tıhmınlıoğlu, Funda; Ülkü, SemraClinoptilolite-type natural zeolite, which exists in various regions of Turkey, has been experimentally studied. For the ethanol-water-local clinoptilolite system, uptake and breakthrough curves were determined under a nitrogen gas atmosphere. In adsorption kinetics and adsorption equilibrium studies, the effects of particle size, temperature and, amount of zeolite on the uptake rate have been investigated. The breakthrough curves for four different flow rates of ethanol and three different bed heights were determined in dynamic column studies. The results of the experiments show that intraparticle diffusion is the main resistance. The local clinoptilolite is a promising adsorbent for water adsorption from aqueous ethanol.