Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
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Article Effect of Marination on the Formation of Polycyclic Aromatic Hydrocarbons in Grilled Vegetables(Wiley, 2025) Kacmaz Ozcetin, Sibel; Artok, LeventThe effect of marination on the formation of polycyclic aromatic hydrocarbons (PAH) in charcoal-grilled vegetables was studied. Various marinade ingredients, including apple cider vinegar, red grape vinegar, lemon juice, garlic powder, black pepper, and the food additive tert-butylhydroquinone (TBHQ) were applied to vegetable samples before charcoal grilling. The total phenolic content (TPC) and total antioxidant capacity (TAC) of each marinade ingredient were assessed for their contribution to PAH inhibition. A substantial decrease in PAH4 formation was observed in marinated vegetables. Red grape vinegar exhibited the strongest average inhibitory effect on total PAH4 formation (75%), followed by apple vinegar (68%), lemon juice (52%), garlic powder (34%), and black pepper (30%). Additionally, the TBHQ (67%) demonstrated a strong inhibitory effect, reducing total PAH4 formation by 67%. These findings offer valuable insights for reducing PAH levels in grilled vegetables and preventing their formation.Article Citation - WoS: 15Search for Supersymmetry in pp Collisions at √s=7 TeV in Events With a Single Lepton, Jets, and Missing Transverse Momentum(Springer, 2013) Chatrchyan, S.; Khachatryan, V.; Sirunyan, A. M.; Tumasyan, A.; Adam, W.; Aguilo, E.; Swanson, J.Results are reported from a search for new physics processes in events containing a single isolated high-transverse-momentum lepton (electron or muon), energetic jets, and large missing transverse momentum. The analysis is based on a 4.98 fb(-1) sample of proton-proton collisions at a center-of-mass energy of 7 TeV, obtained with the CMS detector at the LHC. Three separate background estimation methods, each relying primarily on control samples in the data, are applied to a range of signal regions, providing complementary approaches for estimating the background yields. The observed yields are consistent with the predicted standard model backgrounds. The results are interpreted in terms of limits on the parameter space for the constrained minimal supersymmetric extension of the standard model, as well as on cross sections for simplified models, which provide a generic description of the production and decay of new particles in specific, topology based final states.Article Plasma Proteomic Markers of Interleukin-1β Pathway Associated With Incident Age-Related Macular Degeneration in Persons With Aids(Elsevier, 2025) Hunt, Peter W.; Olshen, Adam B.; Murad, Natalia; Ambayec, Gabrielle C.; Sezgin, Efe; Schneider, Michael F.; Jabs, Douglas A.Objective To evaluate the associations of plasma inflammatory proteins with age-related macular degeneration (AMD) in persons with the AIDS, using a discovery-based proteomics approach. Design A nested case-control study (analysis 1) and nested cohort study (analysis 2). Participants Persons with AIDS enrolled in the Longitudinal Study of the Ocular Complications with AIDS (LSOCA). Methods Cryopreserved plasma specimens obtained at baseline were assayed for inflammatory proteins using the Olink Inflammation Explore Panel 1. In analysis 1, baseline proteomic profiles for 26 persons with AIDS and incident intermediate-stage AMD 5 to 10 years after baseline and 49 matched controls (matched for age, biologic sex, race/ethnicity, and follow-up) without AMD were compared. In analysis 2, 475 persons from LSOCA with baseline plasma inflammatory proteomic profile measurements were followed for incident cataract and mortality. Main Outcome Measures Incident intermediate-stage AMD; incident cataract; and mortality. Results Of 365 measurable plasma inflammatory proteins, 118 (32%) were associated with incident intermediate-stage AMD at the false discovery rate-adjusted Q < 0.05 level after adjustment for smoking, CD4+ T count, and plasma human immunodeficiency virus RNA level. Gene ontology pathway enrichment analysis identified the interleukin (IL)-1 beta pathway and wound healing pathways, including tissue inhibitor of metalloproteinase 3, as significantly associated with incident AMD. These associations were qualitatively different from those associated with incident cataracts, where elevated levels of inflammatory proteins were associated with a decreased risk of cataracts. A much broader number of inflammatory pathways, including those related to the adaptive immune system, were associated with mortality. Conclusions Upregulation of the IL-1 beta pathway appears to be associated with an increased risk of incident AMD in persons with AIDS. Given the availability of inhibitors of this pathway, inhibition of the IL-1 beta pathway may provide a therapeutic avenue for treatment of AMD. Financial Disclosure(s) Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article. Ophthalmology Science 2025;5:100794 (c) 2025 by the American Academy of Ophthalmology. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).Article Citation - WoS: 8Citation - Scopus: 8A Review of the Experimental and Numerical Studies on the Compression Behavior of the Additively Produced Metallic Lattice Structures at High and Low Strain Rates(KeAi Communications Co., 2025) Bin Riaz, Muhammad Arslan; Guden, MustafaRecent advances in additive manufacturing have enabled the construction of metallic lattice structures with tailored mechanical and functional properties. One potential application of metallic lattice structures is in the impact load mitigation where an external kinetic energy is absorbed by the deformation/ crushing of lattice cells. This has motivated a growing number of experimental and numerical studies, recently, on the crushing behavior of additively produced lattice structures. The present study overviews the dynamic and quasi-static crushing behavior of additively produced Ti64, 316L, and AlSiMg alloy lattice structures. The first part of the study summarizes the main features of two most commonly used additive processing techniques for lattice structures, namely selective-laser-melt (SLM) and electrobeam-melt (EBM), along with a description of commonly observed process induced defects. In the second part, the deformation and strain rate sensitivities of the selected alloy lattices are outlined together with the most widely used dynamic test methods, followed by a part on the observed microstructures of the SLM and EBM-processed Ti64, 316L and AlSiMg alloys. Finally, the experimental and numerical studies on the quasi-static and dynamic compression behavior of the additively processed Ti6 4, 316L, and AlSiMg alloy lattices are reviewed. The results of the experimental and numerical studies of the dynamic properties of various types of lattices, including graded, non-uniform strut size, hollow, non-uniform cell size, and bio-inspired, were tabulated together with the used dynamic testing methods. The dynamic tests have been noted to be mostly conducted in compression Split Hopkinson Pressure Bar (SHPB) or Taylor-and direct-impact tests using the SHPB set-up, in all of which relatively small-size test specimens were tested. The test specimen size effect on the compression behavior of the lattices was further emphasized. It has also been shown that the lattices of Ti6 4 and AlSiMg alloys are relatively brittle as compared with the lattices of 316L alloy. Finally, the challenges associated with modelling lattice structures were explained and the micro tension tests and multi-scale modeling techniques combining microstructural characteristics with macroscopic lattice dynamics were recommended to improve the accuracy of the numerical simulations of the dynamic compression deformations of metallic lattice structures. (c) 2025 China Ordnance Society. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/ licenses/by-nc-nd/4.0/).Article Citation - WoS: 1Legume and Nut Flours From the Mediterranean Area: Proximate Compositions, Techno-Functionalities, and Spectroscopy Patterns as a Function of Species, Origin, and Treatment(Elsevier, 2025) Cappa, Carola; Ozen, Banu; Tokatli, Figen; Imeneo, Valeria; Aguilo-Aguayo, Ingrid; Sahan, Yasemin; Alamprese, CristinaThis study systematically evaluates proximate composition, color, techno-functionalities, and spectroscopy patterns of 19 legume and 16 nut commercial flours of the Mediterranean area. Effect of species, origin, and treatment were analyzed using a Generalized Linear Model. Except for legume proteins, species and origin significantly (p <= 0.001) affected flour composition, while heat treatment only had a significant effect (p <= 0.05) on nuts. A large variability was observed in fats (0.6-69 g/100g) and proteins (3.7-36 g/100g), and the FT-IR spectra reflected the 35-flours composition. Principal component model clearly distinguished flours based on their carbohydrate, fat, and protein contents. For legumes, color indices, bulk density, and emulsifying properties were significantly affected by species, origin, and treatment, while foaming properties were influenced only by species. For nuts, oil absorption capacity, emulsion properties, and foaming properties were significantly affected by species, origin, and treatment. The origin had a significant effect on water retention capacity (40-433 %) of nuts. The study findings contribute to a better knowledge of Mediterranean legume and nut flours, clarifying their distinct properties for a higher awareness in their use for the design of food products with tailored features.Article Citation - WoS: 2Citation - Scopus: 1Cross-Linked Carboxymethyl Cellulose Biosorbent for Zinc Removal: a Sustainable Remediation of Heavy Metal-Polluted Waters(Springer Heidelberg, 2025) Celgan, Dilber; Karadag, Asiye; Karim, Barna Jalaluddin Mohammad; Recepoglu, Yasar Kemal; Arar, OzgurThis study focuses on the preparation and characterization of cross-linked carboxymethyl cellulose (CMC) biosorbent for efficient removal of Zn2(+) ions from aqueous solutions. The microstructural features of the biosorbent were examined using scanning electron microscopy (SEM), while elemental analysis was conducted using an elemental analyzer to determine carbon (C), hydrogen (H), nitrogen (N), and sulfur (S) content. Fourier transform infrared (FTIR) spectroscopy was employed to identify functional groups within the biosorbent. Sorption experiments revealed that increasing the biosorbent dose led to higher Zn2(+) removal rates until equilibrium was reached. The optimal pH for Zn2(+) removal was determined to be >= 5, attributed to the conversion of acetate group to its ionic form. Rapid kinetics were observed, with 99% removal achieved within 5 min. The biosorbent exhibited a maximum sorption capacity of 10.809 mg/g and a removal rate of 99% at pH 5. Desorption studies demonstrated efficient Zn2(+) recovery using 0.25 M HCl solution, with a total desorption rate exceeding 99%. The findings indicate the potential for cost-effective regeneration of the biosorbent using dilute acid solutions, enhancing its sustainability and practical applicability in water purification processes. Additionally, the biosorbent's selectivity for Zn2(+) ions over competing ions and its effectiveness in treating real water samples, including those containing Na+, K+, Ca2(+), and Mg2(+), highlight its suitability for practical water purification applications.Article Citation - WoS: 1Citation - Scopus: 1Tracing the Origins: Byzantine Lime Mortars From Anaia and St. Jean Churches (Western Türkiye) and Provenances of Natural Stone Aggregates(Springer Heidelberg, 2025) Aydinalp, Tugce; Uzelli, Taygun; Sagin, Elif UgurluThe aim of this study is to determine the provenances of natural stone aggregates of the lime mortars from the St. Jean and Anaia Churches, which represent two of the most significant Byzantine buildings in Western T & uuml;rkiye. With this aim, the characterization study was conducted to define the physical properties and raw material compositions of lime mortars; hydraulic properties of the binders; mineralogical and chemical compositions, microstructural properties of lime, binders and aggregates; geochemical characteristics and pozzolanic activities of aggregates. The analyses were determined using X-ray diffraction (XRD), scanning electron microscopy coupled with energy dispersive spectroscopy (SEM-EDS), and thermogravimetric analysis (TGA). Furthermore, field observations and analytical studies were paired with the characterization results to determine the possible provenances. Analytical studies demonstrated that natural stone aggregates exhibited highly pozzolanic properties, which imparted hydraulicity to lime mortars. The macrostructure of the natural stone aggregates exhibited angular characteristics and a diverse lithological composition derived from the older brecciated clastics of the Menderes Massif. The fine-grained volcanic matrix of the aggregates was predominantly dacitic or rhyolitic in character, possibly derived from a breccia matrix composed of volcaniclastic materials. The findings suggested that the provenance of the natural stone aggregates were the breccia accumulation regions around Ayasuluk (Sel & ccedil;uk) for the St. Jean Church and S & ouml;ke-Germencik for the Anaia Church. The deliberate selection of natural stone sources to produce hydraulic lime mortars shows a conscious relationship with the surrounding geology during the Byzantine period.Article Citation - WoS: 1Citation - Scopus: 1Improved Isolation of Ultra-High Genomic Dna Suitable for Third-Generation Sequencing(Mdpi, 2025) Ova, Ayse Oyku; Joffre, Enrique; Shafagh, Reza Zandi; Assuncao, Mariana F. G.; Sidorov, Roman Y.; Santos, Lilia M. A.; Romling, UteAlthough a variety of protocols to isolate high-molecular-weight genomic DNA exist, the isolation and preservation of ultra-high-molecular-weight genomic DNA of sufficient quality and length for error-free third-generation sequencing remains challenging. Inspired by the isolation of high-molecular-weight DNA in agarose plugs suitable to be separated by pulsed-field gel electrophoresis, we report the construction of an incubation chamber for DNA isolation. The chamber is flanked by semi-permeable polycarbonate membranes of variable pore size for the selective diffusion of compounds and components, which allows efficient cell lysis and the subsequent isolation of ultra-high-molecular-weight genomic DNA without shearing. The designed experimental approach is simple, but effective in isolating high-quality ultra-long genomic DNA that is suitable for third-generation sequencing by Oxford Nanopore Technology from challenging bacterial samples. We envisage that genomic DNA isolation using the incubation chamber, or variations thereof, will facilitate the regular sequencing of megabasepair-long DNA fragments, with a multitude of applications in microbiology, immunology, oncology, paleontology and forensic science.Article Citation - WoS: 4Citation - Scopus: 4Sulfonated Cellulose: a Strategy for Effective Methylene Blue Sequestration(Amer Chemical Soc, 2025) Toy, Mustafa; Recepoglu, Yasar Kemal; Arar, OzgurThis study investigates the sulfonation modification of cellulose for the removal of methylene blue (MB) from aqueous solutions. The prepared biosorbent was characterized, and its sorption capacity, kinetics, and thermodynamics were systematically evaluated. Fourier-transform infrared (FTIR) spectroscopy analyzed structural modifications, while scanning electron microscopy (SEM) examined the surface properties. The optimal sorbent dosage was determined as 0.05 g. MB removal efficiency increased from 11% at pH 1 to 70% at pH 2, reaching 99% within the pH range of 3 to 7. Kinetic studies revealed rapid sorption, achieving 99% removal within 3 min. Among various isotherm models, the Langmuir model provided the best fit (R 2 = 0.9989), indicating monolayer sorption with a maximum capacity of 37.65 mg/g. Thermodynamic analysis showed negative Delta G degrees values, confirming a spontaneous sorption process, while an enthalpy change (Delta H degrees) of -33.5 kJ/mol indicated exothermic behavior. The entropy change (Delta S degrees) of -82.6 J mol-1<middle dot>K-1 suggested decreased disorder during sorption. Regeneration studies demonstrated that 0.2 M HCl combined with ethanol achieved the highest desorption efficiency, and after three cycles, the MB removal efficiency remained above 99%. The presence of -SO3 - groups played a crucial role in MB sorption via ion exchange and may also contribute through hydrogen bonding, thereby enhancing MB sorption. These findings highlight sulfonated cellulose as an efficient and regenerable biosorbent for MB removal, offering valuable insights into its sorption mechanisms.Article Citation - WoS: 3Citation - Scopus: 2Cradle-To Life Cycle Assessment of Heavy Machinery Manufacturing: a Case Study in Türkiye(Springer, 2025) Üçtuğ, F.G.; Ediger, V.Ş.; Küçüker, M.A.; Berk, İ.; İnan, A.; Moghadasi Fereidani, B.Purpose: Amidst accelerated industrialization and urbanization, the surge in heavy equipment production, crucial for construction, mining, industry, and transportation, necessitates a comprehensive examination of its environmental implications from a sustainability standpoint. This study aims to scrutinize the environmental impacts of manufacturing forklifts and semi-trailers in Türkiye, employing the life cycle assessment (LCA) methodology. Methods: The life cycle assessment (LCA) methodology is the foundational framework for evaluating the environmental impacts associated with forklift and semi-trailer manufacturing. A cradle-to-gate approach was employed. CCaLC2 software alongside the Ecoinvent 3.0 database and CML LCIA methodology was used. Results: The carbon footprint analysis reveals that the production of a single forklift and semi-trailer generates 10.8 tons CO2eq. and 24.9 tons CO2eq. of emissions, respectively. Considering the mass of the machinery, these figures translate to 2.8 ton CO2eq./ton machinery and 1.57 ton CO2eq/ton machinery for the forklift and semi-trailer, respectively. These results were found to be consistent with values reported for similar (but not identical) heavy machinery. Notably, the predominant share of environmental impact stems from raw material acquisition for both products, with subsequent contributions from various production stages. Steel utilization emerges as the primary contributor to all environmental impact categories, constituting an average contribution of 75%. Noteworthy exceptions include the acidification potential of forklift production, where the incorporation of the engine emerges as the primary hotspot with a significant 38% contribution. Conclusions: The findings present the environmental footprint associated with forklift and semi-trailer manufacturing, emphasizing the pivotal role of raw material acquisition, particularly steel utilization. Insights derived from this environmental impact assessment provide invaluable guidance for enhancing environmental sustainability. Decision-makers and industry stakeholders can leverage these conclusions to implement targeted measures, such as exploring alternative materials or refining production processes, to mitigate the environmental consequences of resource-intensive heavy equipment manufacturing, aligning with broader sustainability objectives. © The Author(s) 2025.