Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
Browse
462 results
Filters
Settings
Search Results
Conference Object Determination of Interfacial Heat Transfer Coefficient for a Mixed Convection Heat Transfer in a Vertical Channel Filled With Uniformly Heated Blocks(Begell House Inc., 2015) Çelik, Hasan; Mobedi, Moghtada; Manca,O.; Buonomo,B.The interfacial convective heat transfer coefficient of a periodic porous medium under mixed convection heat transfer is determined computationally by using volume averaging method. The porous medium consists of square blocks in inline arrangement. The continuity, momentum and energy equations are solved in dimensionless form for a representative elementary volume of porous medium and the velocity and temperature fields for different values of Richardson and Reynolds numbers are obtained. Based on the obtained results, the interfacial convective heat transfer coefficient is calculated by using volume average method. The temperature of the solid phase is considered uniform and different than the inlet temperature. A detailed discussion on the effect of the governing dimensionless parameters (i.e. Reynolds, Richardson numbers, and porosity) on the local and average interfacial Nusselt number is done. It is concluded that the local interfacial convective heat transfer coefficient increases with Reynolds number, however the rate of increase depends on Richardson number and porosity. The study is performed for two values of porosity of 0.51 and 0.94. © 2021, Begell House Inc. All rights reserved.Conference Object A Numerical Study on the Determination of the Effects of Pore To Throat Size Ratio on the Thermal Dispersion in Porous Media(Begell House, 2014) Özgümüş, Türküler; Mobedi, Moghtada; Özkol, ÜnverDirect pore-level numerical simulations are widely used to estimate macroscopic properties of fluid flow and heat transfer in porous media. Thermal dispersion is one of the most important macroscopic transport parameters for analyzing convective heat transfer in a porous medium. It should be known in order to predict the macroscopic temperature distribution. In the present study, a microscopic scale analysis is performed for a porous medium with periodic structure. A representative elementary volume is chosen from an infinite medium consists of rectangular rods in inline arrangement. The continuity and momentum equations are solved to obtain flow field and the energy equations for fluid and solid phases are solved to obtain microscopic temperature distributions in two phases. There are velocity and temperature deviations between macroscopic and microscopic local values. Volume averaging method is applied to the computed deviations and thermal dispersion conductivity of porous media is determined. The aim of this study is to analyze the effects of pore to throat size ratio on the longitudinal and transverse thermal dispersion in porous media. The study is performed for representative elementary volumes with different pore to throat size ratios and Reynolds numbers from 1 to 100. The study is performed for high porosity porous media (ε = 0.7 and 0.91). It is shown that the porosity and pore to throat size ratio have more influence on the transverse rather than longitudinal thermal dispersion. © 2014, Begell House Inc. All rights reserved.Article Citation - WoS: 21Citation - Scopus: 24Development and Mechanical Behavior of Fml/Aluminium Foam Sandwiches(Springer Verlag, 2013) Baştürk, Suat Bahar; Tanoğlu, MetinIn this study, the Fiber-Metal Laminates (FMLs) containing glass fiber reinforced polypropylene (GFPP) and aluminum (Al) sheet were consolidated with Al foam cores for preparing the sandwich panels. The aim of this article is the comparison of the flexural properties of FML/Al foam sandwich panels bonded with various surface modification approaches (silane treatment and combination of silane treatment with polypropylene (PP) based film addition). The FML/foam sandwich systems were fabricated by laminating the components in a mould at 200 A degrees C under 1.5 MPa pressure. The energy absorbtion capacities and flexural mechanical properties of the prepared sandwich systems were evaluated by mechanical tests. Experiments were performed on samples of varying foam thicknesses (8, 20 and 30 mm). The bonding among the sandwich components were achieved by various surface modification techniques. The Al sheet/Al foam sandwiches were also consolidated by bonding the components with an epoxy adhesive to reveal the effect of GFPP on the flexural performance of the sandwich structures.Article Citation - WoS: 1Citation - Scopus: 2Emergence of Taperedducts in Vascular Designs With Laminar and Turbulent Flows(Begell House, 2014) Çetkin, ErdalHere we show that tapered ducts emerge in volumetrically bathed porous materials to decrease the resistance to the flow in laminar and turbulent flow regimes. The fluid enters the volume from one point and it is distributed to the entire volume. After bathing the volume, it is collected and leaves the volume from another point, i.e., two trees matched canopy to canopy. This paper shows that the flow architecture (i.e., design of the void spaces in a porous material) should be changed to obtain the minimum resistance to the flow as its size increases. Tapering the ducts decreases the order of the transition size, i.e., the size for changing from one construct to another to obtain the minimum pressure drop. The decrease in the pressure drop is 16% and 38% with the tapered ducts when the flow is laminar and turbulent, respectively. In addition, the volume ratios and the shape of the tapered ducts are documented. There is no design existing in nature with diameters of constant size in order to distribute and/or collect heat, fluid, and/or stress such as bones, rivers, veins, and tree branches. The emergence of the tapered ducts in designed porous materials is natural.Article Citation - WoS: 21Citation - Scopus: 22Daily Application of Low Magnitude Mechanical Stimulus Inhibits the Growth of Mda-Mb Breast Cancer Cells in Vitro(BioMed Central Ltd., 2014) Ölçüm, Melis; Özçivici, EnginIntroduction: Mechanical loads can regulate cell proliferation and differentiation at various stages of development and homeostasis. However, the extension of this regulatory effect of mechanical loads on cancer cells is largely unknown. Increased physical compliance is one of the key features of cancer cells, which may hamper the transmission of mechanical loads to these cells within tumor microenvironment. Here we tested whether brief daily application of an external low magnitude mechanical stimulus (LMMS), would impede the growth of MDA-MB-231 aggressive type breast cancer cells in vitro for 3 wks of growth. Methods: The signal was applied in oscillatory form at 90 Hz and 0.15 g, a regimen that would induce mechanical loads on MDA-MB-231 cells via inertial properties of cells rather than matrix deformations. Experimental cells were exposed to LMMS 15 min/day, 5 days/week in ambient conditions while control cells were sham loaded. Cell proliferation, viability, cycle, apoptosis, morphology and migration were tested via Trypan Blue dye exclusion, MTT, PI, Annexin V, Calcein-AM and phalloidin stains and scratch wound assays. Results: Compared to sham controls, daily application of LMMS reduced the number and viability of cancerous MDA-MB-231 cells significantly after first week in the culture, while non-cancerous MCF10A cells were found to be unaffected. Flow cytomety analyses suggested that the observed decrease for the cancer cells in the LMMS group was due to a cell cycle arrest rather than apoptosis. LMMS further reduced cancer cell circularity and increased cytoskeletal actin in MDA-MB-231 cells. Conclusion: Combined, results suggest that direct application of mechanical loads negatively regulate the proliferation of aggressive type cancer cells. If confirmed, this non-invasive approach may be integrated to the efforts for the prevention and/or treatment of cancer.Article Citation - WoS: 12Citation - Scopus: 11Inverted Fins for Cooling of a Non-Uniformly Heated Domain(Yıldız Teknik Üniversitesi, 2015) Çetkin, ErdalThis paper shows that the peak temperature of a non-uniformly heated region can be decreased by embedding high-conductivity tree-shaped inserts which is in contact with a heat sink from its stem. The volume fraction of the high-conductivity material is fixed, and so is the volume of the solid region. The length scale of the solid domain is L. Inside there is a cube-shaped region with length scale of 0.1L and heat production 100 times greater than the rest of the domain. The location of this hot spot was varied to uncover how its location affects the peak temperature and the design of inverted fins, i.e. highconductivity tree-shaped inserts. The volume fraction of the high-conductivity tree was varied for number of bifurcation levels of 0, 1 and 2. This showed that increasing the number of the bifurcation levels decreases the peak temperature when the volume fraction decreases. The optimal diameter ratios and optimal bifurcation angles at the each junction level are also documented. Y-shaped trees promise smaller peak temperatures than T-shaped trees. The location of the vascular tree in the z direction also affects the peak temperature when the heat generation is non-uniform. In addition, the peak temperature is minimum when z = 0.65L even though the hot spot is located on z = 0.75L.Article Citation - WoS: 6Citation - Scopus: 7Effect of an Inserted Porous Layer on Heat and Fluid Flow in a Vertical Channel With Mixed Convection(Vinca Inst Nuclear Sci, 2015) Çelik, Hasan; Mobedi, MoghtadaTemperature and velocity fields in a vertical channel partially filled with porous medium under mixed convection heat transfer condition are obtained. The heat transfer equation and equation of motion for clear and porous layer regions are written and solved analytically. The non-dimensionalization of the governing equations yields two Grashof numbers as Gr(c) and Gr(d) for clear and porous sections where Gr(d) = Da.Gr(c). The dimensionless governing parameters for the problem are Gr(c) (or Gr(d)), Da, thermal conductivity ratio, and thickness of porous layer. The temperature and velocity profiles for different values of Gr(c), Da, thermal conductivity ratio, and thickness of porous layer are plotted and their changes with the governing parameters are discussed. Moreover, the variation of pressure drop with the governing parameters is investigated. The decrease of porous layer thickness or thermal conductivity ratio increases the possibility of the downward flows. Thermal conductivity ratio plays important role on pressure drop, particularly for the channels with high values of Gr(c)/Re.Article Citation - WoS: 3Citation - Scopus: 4Constructal Structures for Self-Cooling: Microvascular Wavy and Straight Channels(Yıldız Teknik Üniversitesi, 2015) Çetkin, ErdalThis paper shows that a conductive domain which is subjected to heating from its bottom can be cooled with embedded microvascular cooling channels in it. The volume of the domain and the coolant are fixed. The actively cooled domain is mimicked from the human skin (which regulates temperature with microvascular blood vessels). The effect of the shape of cooling channels (sinusoidal or straight) and their locations in the direction perpendicular to the bottom surface on the peak and average temperatures are studied. In addition, the effect of pressure difference in between the inlet and outlet is varied. The pressure drop in the sinusoidal channel configurations is greater than the straight channel configurations for a fixed cooling channel volume. The peak and average temperatures are the smallest with straight cooling channels located at y = 0.7 mm. Furthermore, how the cooling channel configuration should change when the heat is generated throughout the volume is studied. The peak and average temperatures are smaller with straight channels than the sinusoidal ones when the pressure drop is less than 420 Pa, and they become smaller with sinusoidal channel configurations when the pressure drop is greater than 420 Pa. In addition, the peak and average temperatures are the smallest with sinusoidal channels for a fixed flow rate. Furthermore, the peak temperatures for multiple cooling channels is documented, and the multiple channel configurations promise to the smallest peak temperature for a fixed pressure drop value. This paper uncovers that there is no optimal cooling channel design for any condition, but there is one for specific objectives and conditions.Article Citation - WoS: 8Citation - Scopus: 8Free Vibration Analysis of Damaged Composite Beams(Techno Press, 2015) Cünedioğlu, Yusuf; Beylergil, BertanIn this study, free vibration analyses of symmetric laminated cantilever and simply supported damaged composite beams are investigated by using finite element method (FEM). Free vibration responses of damaged beams are examined using Euler Bernoulli beam and classical lamination theories. A computer code is developed by using MATLAB software to determine the natural frequencies of a damaged beam. The local damage zone is assumed to be on the surface lamina of the beam by broken fibers after impact. The damaged zone is modeled as a unidirectional discontinuous lamina with 0 degrees orientations in this study. Fiber volume fraction (v(f)), fiber aspect ratio (L-f/d(f)), damage length (L-D) and its location (lambda/L), fiber orientation and stacking sequence parameters effects on natural frequencies are investigated. These parameters are affected the natural frequency values significantly.Article Citation - WoS: 28Citation - Scopus: 30Bone Marrow Stem Cells Adapt To Low-Magnitude Vibrations by Altering Their Cytoskeleton During Quiescence and Osteogenesis(TUBITAK, 2015) Demiray, Levent; Özçivici, EnginApplication of mechanical vibrations is anabolic to bone tissue, not only by guiding mature bone cells to increased formation, but also by increasing the osteogenic commitment of progenitor cells. However, the sensitivity and adaptive response of bone marrow stem cells to this loading regimen has not yet been identified. In this study, we subjected mouse bone marrow stem cell line D1-ORL-UVA to daily mechanical vibrations (0.15 g, 90 Hz, 15 min/day) for 7 days, both during quiescence and osteogenic commitment, to identify corresponding ultrastructural adaptations on cellular and molecular levels. During quiescence, mechanical vibrations significantly increased total actin content and actin fiber thickness, as measured by phalloidin staining and fluorescent microscopy. Cellular height also increased, as measured by atomic force microscopy, along with the expression of focal adhesion kinase (PTK2) mRNA levels. During osteogenesis, mechanical vibrations increased the total actin content, actin fiber thickness, and cytoplasmic membrane roughness, with significant increase in Runx2 mRNA levels. These results show that bone marrow stem cells demonstrate similar cytoskeletal adaptations to low-magnitude high-frequency mechanical loads both during quiescence and osteogenesis, potentially becoming more sensitive to additional loads by increased structural stiffness.