Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection

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  • Article
    Citation - WoS: 1
    Citation - Scopus: 1
    Plasma-Enhanced Cvd Synthesis and Cytotoxic Evaluation of Graphitic Carbon Embedded – Fe3O4 Nanoparticles
    (Elsevier Sci Ltd, 2025) Balci-Cagiran, Ozge; Mertdinc-Ulkuseven, Siddika; Solati, Navid; Onbasli, Kubra; Yagci-Acar, Havva; Agaogullari, Duygu
    This study reports the synthesis of graphitic carbon embedded - Fe3O4 nanoparticles using a novel method that enables a low-temperature rapid process and includes cytotoxicity tests to evaluate their potential use in biomedical applications. In this study, graphitic carbon was grown on Fe3O4 core using a plasma-enhanced chemical vapor deposition (PE-CVD) system under an Ar-H-2-CH4 gas plasma at 650 degrees C for 15 min. X-ray diffractometry (XRD) and Raman spectroscopy investigations confirmed that Fe3O4 nanoparticles were embedded in graphitic carbon (Fe3O4@C). Scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS), along with transmission electron microscopy (TEM) equipped with EDS, also supported the carbon formation and nano-sized structure of the synthesized particles. Fe3O4@C nanoparticles exhibited soft magnetic properties with saturation magnetization (M-s) and coercivity (H-c) values of 69.27 emu/g and 97 Oe, respectively. Cytotoxicity assessment on HeLa and MCF7 cancer cells suggested biocompatibility at and below a dose of 100 mu g/mL after 24 h of exposure but a drop in cell viability at higher doses and longer incubation times, more on cancer cell lines than the healthy L929 cells. These results suggest that Fe3O4@C nanoparticles might be potential candidates for biomedical applications, including drug delivery, photothermal therapy, and magnetically-triggered operations.