Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
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Conference Object Assessment of Drought in Izmir District Using Standardized Precipitation Index(Springer Nature, 2025) Mersin, D.; Gulmez, A.; Safari, M.J.S.; Vaheddoost, B.; Tayfur, G.One of the main issues with agro-food and socio-economical security in the world is droughts. Regardless of cause or effect, the ever-changing climate is placing increasing strain on water resources pushing supply to its limits. Izmir, a growing city in Turkey, is endowed with variety of water resources, such as lakes, rivers, seashores, and groundwater reserves. Therefore, it is crucial for the planning and development of the area to examine past and foreseeable drought occurrences and their possible impact on water resources. In this regard, the study’s goal is to assess historical droughts in Izmir District. Data from three meteorological stations in Küçük Menderes basin, collected between 1973 and 2020, are utilized in this study. To establish the validity of the posterior drought analysis, the consistency and trend in the time series are first examined using the double mass curve, run test, and linear trend analysis. The next step is to assess the historical deficit related to meteorological, agricultural, and hydrological droughts using the SPI and moving mean (MA) operator. The temporal analysis of SPI reveals distinct drought patterns across the stations, with multiple moderate to extreme droughts occurring particularly between 1998 and 2010, highlighting significant spatial and temporal variability in drought severity and frequency. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2025.Article Future Circular Collider Feasibility Study Report: Volume 1 Physics, Experiments, Detectors(Springer Nature, 2025) Benedikt, M.; Zimmermann, F.; Auchmann, B.; Bartmann, W.; Burnet, J.P.; Carli, C.; Alonso, B.A.Volume 1 of the FCC Feasibility Report presents an overview of the physics case, experimental programme, and detector concepts for the Future Circular Collider (FCC). This volume outlines how FCC would address some of the most profound open questions in particle physics, from precision studies of the Higgs and EW bosons and of the top quark, to the exploration of physics beyond the Standard Model. The report reviews the experimental opportunities offered by the staged implementation of FCC, beginning with an electron-positron collider (FCC-ee), operating at several centre-of-mass energies, followed by a hadron collider (FCC-hh). Benchmark examples are given of the expected physics performance, in terms of precision and sensitivity to new phenomena, of each collider stage. Detector requirements and conceptual designs for FCC-ee experiments are discussed, as are the specific demands that the physics programme imposes on the accelerator in the domains of the calibration of the collision energy, and the interface region between the accelerator and the detector. The report also highlights advances in detector, software and computing technologies, as well as the theoretical tools/reconstruction techniques that will enable the precision measurements and discovery potential of the FCC experimental programme. The content and structure of this report are guided by the scope and priorities defined in the mandate of the FCC Feasibility Study. It is therefore not intended to serve as an exhaustive review of the full physics potential of FCC. Several topics, already covered in earlier reports such as the FCC CDR, are not reiterated here or are addressed only briefly, in alignment with the study’s focus. This volume reflects the outcome of a global collaborative effort involving hundreds of scientists and institutions, aided by a dedicated community-building coordination, and provides a targeted assessment of the scientific opportunities and experimental foundations of the FCC programme. © CERN for the benefit of the FCC collaboration 2025.Book Part Food Question in Planning: Perspectives From Two Turkish Metropolis(Springer Nature, 2025) Özçam, Z.; Senalp, S.Ö.This study examines the integration of urban food systems into planning practices within Türkiye's two major metropolises: İzmir and Ankara. Addressing the challenges posed by climate change, urbanization, and economic crises, the research advocates for a transformative approach to urban food systems through socio-ecological and circularity frameworks. It identifies systemic vulnerabilities in the current agri-food systems, including environmental degradation, social inequalities, and inefficiencies in food production, distribution, and consumption. Through qualitative methodologies—semi-structured interviews, ethnographic observations, and content analysis of strategic planning documents—the study explores local agri-food strategies, emphasizing the critical need for holistic urban food planning. While İzmir demonstrates significant progress with its basin-based agricultural strategies, Ankara’s fragmented initiatives reveal a pressing need for cohesive urban food strategies. Both cities struggle with integrating rural-urban food linkages and systemic planning for storage, logistics, and equitable food access. The findings underscore the potential of localized, participatory governance in enhancing food sovereignty and resilience. However, the research highlights that piecemeal strategies remain insufficient to address the multifaceted challenges of food insecurity and environmental sustainability, advocating for comprehensive, equitable, and regenerative urban food systems as critical components of sustainable urban food planning and development. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2024.Book Part Therapeutic and Pharmaceutical Applications of Pegylated Nano-Carriers(Springer Nature, 2025) Shakeri, R.; Mirjalili, S.Z.; Karakus, C.O.; Safavi, M.The coating of the exterior of nanocarriers with polyethylene glycol (PEG; known as “PEGylation”), has emerged as one of the most widely adopted approaches to impart stealth properties to pharmaceutical nanocarrier systems. The PEGylation tactic offers a stealth barrier towards the adsorption of circulatory proteins owing to its hydrophilicity, elasticity, neutralization, and hydration properties. PEGylation dramatically provides sustained drug release benefits, reduces immune sensitivity, as well as improves the systemic circulation period, Overall, PEGylation effectively improves the therapeutic efficacy of the loaded therapeutic moiety in treating target cells and tissues. This chapter offers discussion on drug delivery nanosystems that are developed based on the principle of PEGylation strategy. Furthermore, a detailed account of the pharmaceutical and biomedical applications of PEGylated nanocarriers has also been presented in detail. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2024.Book Part Citation - WoS: 1Citation - Scopus: 1Challenges Faced by Closed Basins From the Perspective of Water Resources: Case Studies From Türkiye(Springer Nature, 2025) Kircicek, Nilufer Tirol; Gungor, Esra Bilgic; Baba, AlperClosed basins form important hydrological systems that provide a variety of benefits to both the environment and humans. This chapter examines the current status of closed basins in Turkiye and analyzes the natural and anthropogenic environmental stressors affecting these regions. Two distinct case studies are covered in this chapter: the Konya Closed Basin (KCB) and the Karakuyu region. Konya Closed Basin has experienced severe drought and sinkhole issues as a result of misapplications and excessive water consumption. The severity and frequency of water-related problems are increasing day by day due to the impact of climate change in the region. Agricultural activity and irrigation needs are high in the Karakuyu region, which is considered a second case study and is a small part of the Kucuk Menderes River Basin. It is hoped that with improved management practices, Karakuyu will not experience the condition of KCB in the future. The final section outlines the recommended practices and precautionary measures for addressing issues associated with closed basins.Book Part Citation - WoS: 2Citation - Scopus: 4Issues and Challenges in Sustainable Usage of Groundwater Resources in Afghanistan(Springer Nature, 2025) Zaryab, Abdulhalim; Nazari, Aref; Farahmand, Asadullah; Yaqubi, Mohammad Saber; Mirzad, Sayed Mohammad Mansoor; Jafari, Zamen; Shams, Ajmal KhanGlobally, Afghanistan is currently a frontrunner in groundwater scarcity due to unplanned urbanization, rapid rise in population, climate change, weak policies, mismanagement, and lack of long-term vision. Frequent weather extremes like droughts and floods and prolonged war and political instability lead the country far away from achieving water security, food reliance and sustainable management of its natural resources. The war situation also refrains in gathering of long-term hydrological data and thus, there is a huge gap in understanding the water resources even better. Furthermore, aids from international organizations are limited in groundwater development and management. This chapter highlights various issues and challenges in sustainable usage and the importance of groundwater in the country. The chapter compiles the research carried out with regard to Afghanistan's quest to manage its groundwater resources more efficiently.Article Citation - Scopus: 5Efficiency Evaluation of Single and Double Tuned Mass Dampers on Building Response Reduction by Considering Soil-Structure Interaction(Springer Nature, 2024) Roozbahan,M.; Turan,G.Tuned mass dampers (TMDs) and multiple tuned mass dampers (MTMDs) are among the simplest, most reliable, and most frequently employed structural control devices. The efficiency of TMDs and MTMDs depends on their parameters, including the mass, frequency ratio, and damping ratio. Several analytical and metaheuristic methods have been proposed for the optimal design of tuned mass dampers. The aims of this study are: (1) to investigate the differences in efficiency between a number of TMD design methods and (2) to evaluate the differences in efficiency between a single TMD and double TMD (DTMD) in reducing the seismic response of structures by considering soil-structure interactions (SSI). In the first numerical study, the effectiveness of TMDs optimized using seven analytical methods, and TMD and DTMD optimized using a metaheuristics algorithm called Mouth Brooding Fish (MBF) in reducing the response of a fifteen-story structure under 22 far-field and 14 near-field earthquakes is compared. In the second example, in addition to the seven analytical-based designed TMDs, and MBF-based TMDs and DTMDs, the Jaya algorithm based, and plasma generation optimization-based designed TMDs are used, and the same procedure is applied to a forty-story structure. The results show that there is no important difference among these methods, which may indicate that the uppermost optimization level for a regular TMD has been reached. Furthermore, the results indicate that the TMD and DTMD are almost equally effective at reducing the seismic response of structures when the SSI effect is taken into consideration. © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2024.Book Part Citation - Scopus: 1Recovery of Metals From Leach Liquors: Biosorption Versus Metal Sulfide Precipitation(Springer Nature, 2024) Kucuker,M.A.Extraction of metals (leaching) is chemical or biochemical processes that utilize acids or microorganisms to enhance the suspension of metals from the primary and secondary sources by making them more amenable to dissolution in aqueous solutions (leachate). Recovery of metals from the leachates is an essential stage supported by additional purification processes such as precipitation of impurities, electrowinning, solvent extraction, chemical or biological adsorption, and ion exchange. In this study, especially biosorption and metal sulfide precipitation are overviewed and discussed. Biosorption is a process by which particular biomass such as bacteria, fungi, yeast, agricultural wastes, algae, and biowastes can able to bind with specific ions or other molecules from aqueous solutions. Metal sulfide precipitation can be highly effective in obtaining a high degree of separation of metal cations from complex leachates. Each of these techniques has advantages and drawbacks. Sometimes, a technique may not be effective in attaining higher metal recovery. Therefore, different recovery techniques are needed to recover the target elements from the complex leachates. Maybe a combination of two or three recovery techniques is required to recover metals from complex leachates. Additionally, the research activity highlighted that metal sulfide precipitation and biosorption processes have to limit factors that could hinder the process scale-up. Thus, more research is needed to evaluate the environmental impacts of metal recovery from leach liquors. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2024.Book Part Citation - Scopus: 3Tomato: Genetics, Genomics, and Breeding of Health-Related Traits(Springer Nature, 2023) Çelik,I.; Gürbüz Çolak,N.; Doğanlar,S.; Frary,A.Tomato (Solanum lycopersicum) is a popular crop due to its versatility and nutritional quality. In addition to its nutritional content, tomato is rich in various phytochemicals that are known to have beneficial effects on human health. These bioactive components include pigments like lycopene and Β-carotene, ascorbic acid (vitamin C), phenolic compounds, polyamines, and glycoalkaloids. Tomato metabolites have various bioactivities such as antihypertensive, antioxidant, anticancer, anti-inflammatory, antidiabetic, antiallergenic, antiatherogenic, antithrombotic, and antimicrobial effects. Research aimed at improving tomato for many of these specific activities is still in its infancy; however, a foundation of knowledge has been established for health-related (HR) traits in the crop. In this chapter, previous works surveying tomato germplasm for HR traits, conventional breeding, and genetic investigation of these characteristics are described. We also discuss research aimed at HR gene mapping and isolation as well as efforts to improve these traits via genetic engineering and genome editing. © Springer Nature Singapore Pte Ltd. 2023.Book Part Avant-Garde Hydrogels as Stem Cell Niche for Cardiovascular Regenerative Medicine(Springer Nature, 2023) Yilmaz,H.D.; Arslan,Y.E.Cardiovascular diseases remain the primary cause of death in the modern world. According to the World Health Organization (WHO), almost 18 million people lose their lives each year due to cardiac dysfunction. Nearly 75% of the cases are related to heart attack, stroke, and heart failure. Furthermore, the limited restoration capacity of the adult cardiac tissue leads to irreversible changes in myocardial injury and ischemia, which seriously increases the mortality rates. Currently, the available therapeutic approaches for cardiovascular dysfunctions mainly depend on pharmaceutical drugs, vascular assist devices, or organ transplantations in severe cases. However, these strategies cannot prevent ischemia-related damages or restore the dysfunction of heart tissue. Besides, there are certain limitations, including donor shortage, thrombosis of the device, immune rejection reactions, and operative morbidity of the patient. Therefore, combining stem cells with outstanding hydrogels has become a critically important phenomenon in treating cardiovascular disease. Today, stem cell-based applications form the pivot point of regenerative treatments due to their differentiation and immunomodulatory capacity. However, due to low cellular retention and the inhomogeneous therapeutic activities, the effectiveness of stem cell regeneration in clinical and preclinical studies is reduced. Hence, the synergetic approaches of the injectable hydrogels with stem cells and subcellular bioactive tools may hold the promises of the next-generation therapies. Over the last decade, various functional hydrogels from natural, synthetic, or decellularized tissue precursors have been developed and investigated for cardiovascular applications. In this chapter, advances in stem cell therapy have been discussed with the latest research on functional hydrogels for cardiovascular regeneration. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2023.