Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
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Book Part Telemedicine Applications for Pandemic Diseases, With a Focus on Covid-19(Elsevier, 2021) Tarim,E.A.; Karakuzu,B.; Oksuz,C.; Tekin,H.C.Dating back to the development of modern medicine, pandemic and epidemic diseases, such as bubonic plague, smallpox, the plague of Justinian, and the Antonine Plague, have caused massive damage to the human race. For instance, more than 200 million people are estimated to have died due to Black Death (bubonic plague) alone. This situation has not changed in near history either. Diseases such as influenza, HIV/AIDS, severe acute respiratory syndrome, Ebola, Middle East respiratory syndrome, and coronavirus disease 2019 (COVID-19), as today, have emerged and threatened the modern human life. The common feature of these diseases can be listed as having a high risk of infection and transmission, rapidly spreading to large areas, and having high mortality rates and causing permanent damage to the body because of the low immunity profile of the exposed population. If the number of cases increases rapidly for these diseases, the capacity of healthcare services can be exceeded and healthcare services can be threatened as well. These characteristics of pandemic diseases force the authorities to take extraordinary precautions such as isolation and quarantine to reduce the risk of infection. However, these applications can make it difficult to provide proper health services to patients. The development of information technologies provides patients an easy and remote access to healthcare services via telemedicine applications. Telemedicine is used for diagnosis and treatment of diseases by following the same practices used in clinics. It also provides care givers a real-time and remote monitoring of their patients, which can be beneficial in terms of reducing the risk of infections and maintaining healthcare services during a pandemic. Authorities can also use these telemedicine applications to track infected patients and get necessary precaution to minimize the infection risk. This chapter introduces the latest telemedicine applications for epidemic and pandemic diseases, especially for COVID-19. These potential applications could improve and transform the current practices for pandemic disease management. © 2022 Elsevier Inc.Article Citation - WoS: 4Citation - Scopus: 4Mobile human ad hoc networks: A communication engineering viewpoint on interhuman airborne pathogen transmission(Elsevier, 2022) Güleç, Fatih; Atakan, Barış; Dressler, FalkoA number of transmission models for airborne pathogens transmission, as required to understand airborne infectious diseases such as COVID-19, have been proposed independently from each other, at different scales, and by researchers from various disciplines. We propose a communication engineering approach that blends different disciplines such as epidemiology, biology, medicine, and fluid dynamics. The aim is to present a unified framework using communication engineering, and to highlight future research directions for modeling the spread of infectious diseases through airborne transmission. We introduce the concept of mobile human ad hoc networks (MoHANETs), which exploits the similarity of airborne transmission-driven human groups with mobile ad hoc networks and uses molecular communication as the enabling paradigm. In the MoHANET architecture, a layered structure is employed where the infectious human emitting pathogen-laden droplets and the exposed human to these droplets are considered as the transmitter and receiver, respectively. Our proof-of-concept results, which we validated using empirical COVID-19 data, clearly demonstrate the ability of our MoHANET architecture to predict the dynamics of infectious diseases by considering the propagation of pathogen-laden droplets, their reception and mobility of humans.Article Citation - WoS: 11Citation - Scopus: 11The Importance of Neopterin in Covid-19: The Prognostic Value and Relation With the Disease Severity(Elsevier, 2022) Rasmi, Yousef; Heidari, Nadia; Kübra Kırboğa, Kevser; Hatamkhani, Shima; Tekin, Burcu; Alipour, Shahryar; Naderi, Roya; Farnamian, Yeghaneh; Akça, İlknurCoronavirus Disease 2019 [COVID-19], caused by severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2], has rapidly evolved into a global health emergency. Neopterin [NPT], produced by macrophages when stimulated with interferon [IFN-]gamma, is an essential cytokine in the antiviral immune response. NPT has been used as a marker for the early assessment of disease severity in different diseases. The leading cause of NPT production is the pro-inflammatory cytokine IFN-. Macrophage activation has also been revealed to be linked with disease severity in SARS-CoV-2 patients. We demonstrate the importance of NPT in the pathogenesis of SARS-CoV-2 and suggest that targeting NPT in SARS-CoV-2 infection may be critical in the early prediction of disease progression and provision of timely management of infected individuals.