Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
Browse
2 results
Search Results
Article Citation - WoS: 62Citation - Scopus: 72Diatomite Reinforced Chitosan Composite Membrane as Potential Scaffold for Guided Bone Regeneration(Elsevier Ltd., 2017) Tamburacı, Sedef; Tıhmınlıoğlu, FundaIn this study, natural silica source, diatomite, incorporated novel chitosan based composite membranes were fabricated and characterized for bone tissue engineering applications as possible bone regeneration membrane. The effect of diatomite loading on the mechanical, morphological, chemical, thermal and surface properties, wettability and in vitro cytotoxicity and cell proliferation on of composite membranes were investigated and observed by tensile test, atomic force microscopy (AFM), Fourier transform infrared spectroscopy (FTIR), thermal gravimetric analysis (TGA), protein adsorption assay, air/water contact angle analysis and WST-1 respectively. Swelling studies were also performed by water absorption capacity determination. Results showed that incorporation of diatomite to the chitosan matrix increased the surface roughness, swelling capacity and tensile modulus of membranes. An increase of about 52% in Young's modulus was achieved for 10 wt% diatomite composite membranes compared with chitosan membranes. High cell viability results were obtained with indirect extraction method. Besides, in vitro cell proliferation and ALP activity results showed that diatom incorporation significantly increased the ALP activity of Saos-2 cells cultured on chitosan membranes. The novel composite membranes prepared in the present study with tunable properties can be considered as a potential candidate as a scaffold in view of its enhanced physical & chemical properties as well as biological activities for bone tissue engineering applications.Conference Object Citation - Scopus: 1Silver and Zinc Oxide Based Nano Powders and Their Polymer Based Nanocomposites for Antibacterial Application(European Conference on Composite Materials, 2014) Abatay, Ezgi; Özmen, Tuğçe; Arslanoğlu, Alper; Tanoğlu, MetinThe microorganisms cause some serious infections. It is a requirement and a necessity to create sterile fields such as hospital, food processing and public places. Composite stones are one of the main building materials that have been used in buildings due to their high resistant to abrasives, chemicals and mechanical impacts. The silver (Ag), zinc oxide (ZnO), and also nano Ag loaded ZnO (ZnO/Ag) nanopowders have demonsrated capability for the preparation of the polymer based antibacterial nanocomposite materials. In this study, Ag/polyester, ZnO/polyester, Ag/ZnO/polyester and their nanocomposites were prepared and tested with various weight fractions. The microstructure and surface morphology of these nanocomposites were investigated by means of scanning electron microscopy (SEM/EDX). The thermal properties were analyzed by differential scanning calorimetry (DSC) and thermal gravimetric analysis (TGA). Finally, The antibacterial properties of nanocomposites were analyzed against gram positive (Bacillus subtilis) and gram negative bacteria (Escherichia coli).