Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/11147/7148

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  • Article
    Citation - Scopus: 1
    Recent Advances in Hydrogel-Based 3D Disease Modeling and Drug Screening Platforms
    (2025) Bilginer-Kartal, R.; Çoban, B.; Yildirim-Semerci, Ö.; Arslan-Yildiz, A.
    Three-dimensional (3D) disease modeling and drug screening systems have become important in tissue engineering, drug screening, and development. The newly developed systems support cell and extracellular matrix (ECM) interactions, which are necessary for the formation of the tissue or an accurate model of a disease. Hydrogels are favorable biomaterials due to their properties: biocompatibility, high swelling capacity, tunable viscosity, mechanical properties, and their ability to biomimic the structure and function of ECM. They have been used to model various diseases such as tumors, cancer diseases, neurodegenerative diseases, cardiac diseases, and cardiovascular diseases. Additive manufacturing approaches, such as 3D printing/bioprinting, stereolithography (SLA), selective laser sintering (SLS), and fused deposition modeling (FDM), enable the design of scaffolds with high precision; thus, increasing the accuracy of the disease models. In addition, the aforementioned methodologies improve the design of the hydrogel-based scaffolds, which resemble the complicated structure and intricate microenvironment of tissues or tumors, further advancing the development of therapeutic agents and strategies. Thus, 3D hydrogel-based disease models fabricated through additive manufacturing approaches provide an enhanced 3D microenvironment that empowers personalized medicine toward targeted therapeutics, in accordance with 3D drug screening platforms. © 2025. The Author(s), under exclusive license to Springer Nature Switzerland AG.
  • Article
    Fab Lab Toys From a Second-Grade Industrial Design Studio: Expanding the Boundaries of Toy Design
    (Common Ground Research Networks, 2024) Talu,N.; Yurt,C.; Çolak,C.
    This study delves into the seven-week toy design process within a second-grade industrial design undergraduate studio. The foundation of this studio lies in a creative design brief that centers on a closely interconnected triad of concepts: opportunity, challenge, and expectation. The Fab Lab environment serves as an ideal platform and opportunity for generating toy designs within the realm of design education. The intention is to challenge the conventional landscape of mass-produced toys and prevalent toy categories in consumer culture through Fab Lab–produced toys. The expectation is to design toys that transcend these established categories, catering more effectively to the unstructured playtime of children aged 3 to 6. This process aspires to harness contemporary technologies like 3D printing in design education to equip students with skills not only for tackling novel and present challenges but also for addressing critical contexts. The symbiotic relationship between the design education process and experiential prototyping elevates students’ understanding of real-world implications and nurtures their creativity within the design journey. The culmination of this process yields multi-category toy designs poised to enrich the free play experiences of children aged 3 to 6. © 2024 Common Ground Research Networks. All rights reserved.