Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
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Article Antidiabetic and Anticancer Properties of Sun-Dried Fig (Ficus Carica) Stalk Pectin: Effects on Intestinal Glucose Absorption and Colon Cancer Cell Growth(Elsevier, 2025) Baser, Filiz; Cavdaroglu, Elif; Yemenicioglu, Ahmet; Gulec, SukruThis study aims to characterize the physiological activity of fig stalk pectin (FSP) in terms of antidiabetic and anticancer activities. Also, the potency of FSP has been interpreted as a functional food ingredient in yogurt. The galacturonic acid content (65 %), degree of esterification (63 %), and enzymatic sugar analysis showed that FSP is a high methoxyl pectin rich in RG-I content (similar to 22 %). Anti-diabetic characteristics of FSP demonstrated that FSP inhibited 2-deoxyglucose uptake into CaCo-2 cells and reduced glucose absorption in the intestinal transport system after being added as an ingredient in yogurt at the concentration of 2 % (w/w). The antidiabetic activity of FSP was attributed to its capacity to modify the rheological properties of yogurt with a high-water binding capacity (10 g/g), and it increased the viscosity of digested yogurt samples considerably (from 89 to 110 Cp). Moreover, the characterization of anticancer properties showed that FSP inhibited the proliferation of colon cancer CaCo-2 cells by disturbing cell cycle progression, leading to S phase arrest, and showing apoptosis-inducing ability. Further research, including in vivo and clinical trials, is necessary to validate the observed health benefits of FSP.Article Citation - WoS: 1Citation - Scopus: 1Light-Dark and Activity Rhythm Therapy (l-Dart) To Improve Sleep in People With Schizophrenia Spectrum Disorders: a Single-Group Mixed Methods Study of Feasibility, Acceptability and Adherence(MDPI, 2023) Faulkner, Sophie; Didikoğlu, Altuğ; Byrne, Rory; Drake, Richard; Bee, PennyPeople with a diagnosis of schizophrenia often have poor sleep, even when their psychotic symptoms are relatively well managed. This includes insomnia, sleep apnoea, hypersomnia, and irregular or non-24 h sleep-wake timing. Improving sleep would better support recovery, yet few evidence-based sleep treatments are offered to this group. This paper presents a mixed methods feasibility and acceptability study of Light-Dark and Activity Rhythm Therapy (L-DART). L-DART is delivered by an occupational therapist over 12 weeks. It is highly personalisable to sleep phenotypes and circumstances. Ten participants with schizophrenia spectrum diagnoses and sleep problems received L-DART; their sleep problems and therapy goals were diverse. We measured recruitment, attrition, session attendance, and adverse effects, and qualitatively explored acceptability, engagement, component delivery, adherence, activity patterns, dynamic light exposure, self-reported sleep, wellbeing, and functioning. Recruitment was ahead of target, there was no attrition, and all participants received the minimum 'dose' of sessions. Acceptability assessed via qualitative reports and satisfaction ratings was good. Adherence to individual intervention components varied, despite high participant motivation. All made some potentially helpful behaviour changes. Positive sleep and functioning outcomes were reported qualitatively as well as in outcome measures. The findings above support testing the intervention in a larger randomised trial ISRCTN11998005.Book Part Designing Healthier Cities. an Empirical Study of the Ecosystem Functioning and Mortality in the Districts of Turin (italy)(Springer, 2022) Salata, StefanoThe twenty-first century is called “the age of the metropolises and cities” as they become the predominant living environments of human beings. Nonetheless, metropolitan areas are more vulnerable, for their intrinsic nature is dense and interconnected. The experience from the COVID-19 crisis teaches us how an epidemic outburst has been generated by reducing habitat at the planetary scale, and how the quality of the environment even affects the diffusion of the virus. But what is the relation between Health and Nature in urban areas? Is this relation so evident? Within this study, a preliminary assessment of the relations between urban environment and health will be evaluated by modelling the spatial distribution of the Habitat Quality in Turin and the mortality rates in the same areas. Data will be gathered at their maximum spatial precision, thus obtaining a reliable map of the distribution between the two indicators at the district level. Habitat Quality will be composed by the value of the supporting biophysical function and anthropic threats. Health will be evaluated using the death number in the statistical units and the accessibility of citizens to green areas. An overall assessment will be finally presented considering the simultaneous evaluation of spatial clusters and delineating how conservation and valorization measures can benefit from a site-specific evaluation of Ecosystem Services, while revealing their effects on human health.Article Citation - WoS: 39Citation - Scopus: 47Quality of Groundwater Resources in Afghanistan(Springer Verlag, 2017) Hayat, Ehsanullah; Baba, AlperWater is the main source of energy production and economy in Afghanistan where agriculture accounts for more than 50% of the country’s gross domestic product (GDP). Access to safe drinking water is still a problem in the country, which has caused different health issues and even child mortality especially in rural areas. Groundwater is the main source of drinking water in the country. However, little knowledge is available about the quality of groundwater throughout the entire country, and its quality has not been investigated extensively yet like in other countries in the world. While most people think that consuming groundwater is a reliable and safe source of drinking water for health, the United Nations (UN) agencies report various kinds of waterborne diseases and even child mortalities due to drinking water quality in the country. In this article, significant geogenic and anthropogenic factors that play a vital role in groundwater contamination of the country are identified and explained. Different geogenic contaminations such as arsenic, fluoride, sulfate, and boron occur in several areas of Afghanistan that have a direct effect on human health. The water quality mapping for Afghanistan is completed for half of the country, which shows that groundwater is plagued by high levels of fluoride and arsenic in some areas. The water quality mapping of the other half of the country cannot be completed due to security concerns currently. Also, there are different kinds of waterborne diseases such as diarrhea, cholera, and dysentery that can be seen in different parts of the country because of anthropogenic activities which continuously deteriorate groundwater.Article Citation - WoS: 73Citation - Scopus: 84Groundwater Contamination and Its Effect on Health in Turkey(Springer Verlag, 2011) Baba, Alper; Tayfur, GökmenThe sources of groundwater pollution in Turkey are identified, and pathways of contaminants to groundwater are first described. Then, the effects of groundwater quality on health in Turkey are evaluated. In general, sources of groundwater contamination fall into two main categories: natural and anthropogenic sources. Important sources of natural groundwater pollution in Turkey include geological formations, seawater intrusion, and geothermal fluid(s). The major sources of anthropogenic groundwater contamination are agricultural activities, mining waste, industrial waste, on-site septic tank systems, and pollution from imperfect well constructions. The analysis results revealed that natural contamination due to salt and gypsum are mostly found in Central and Mediterranean regions and arsenic in Aegean region. Geothermal fluids which contain fluoride poses a danger for skeleton, dental, and bone problems, especially in the areas of Denizli, Isparta, and AydIn. Discharges from surface water bodies contaminate groundwater by infiltration. Evidence of such contamination is found in Upper KIzIlIrmak basin, Gediz basin, and Büyük Melen river basin and some drinking water reservoirs in Istanbul. Additionally, seawater intrusion causes groundwater quality problems in coastal regions, especially in the Aegean coast. Industrial wastes are also polluting surface and groundwater in industrialized regions of Turkey. Deterioration of water quality as a result of fertilizers and pesticides is another major problem especially in the regions of Mediterranean, Aegean, Central Anatolia, and Marmara. Abandoned mercury mines in the western regions of Turkey, especially in Çanakkale, Izmir, Muǧla, Kütahya, and BalIkesir, cause serious groundwater quality problems. © 2011 Springer Science+Business Media B.V.