Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
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Conference Object A General Predictive Model to Evaluate Daylight Levels of Residential Buildings in the Mediterranean (Next Med) Region(Education and Research in Computer Aided Architectural Design in Europe, 2025) Ekici, B.Conceptual design is one of the most critical phases, as design decisions affect the buildings’ performance throughout their life cycle. Researchers consider various computational methods to achieve effective design proposals. Nevertheless, optimization algorithms are necessary to cope with the complexity and increase the efficiency of design alternatives in various aspects. In sustainable building design, these decisions require computationally expensive processes due to the simulation tasks. Besides, making sustainable design decisions is even more challenging in a Mediterranean climate due to changing conditions throughout the year. Therefore, recent studies frequently consider combining predictive models with optimization algorithms to decrease the burden of expensive simulation time. Relevant works present promising outcomes, yet they are limited to predicting the building performance of specific cases; thus, the proposed predictive models are limited to different design problems. This paper investigates the development of a general machine learning (ML) model to overcome this issue. With this motivation, a parametric test box consisting of twenty parameters related to weather data of twelve Mediterranean (Next Med) countries, space dimensions, vertical/horizontal louvers, and material type is developed using Grasshopper 3d. Moreover, a parametric urban model, which considers eight parameters related to the density of the surrounding buildings, is also created to generate numerous environments. The LadyBug tools simulate the daylight autonomy to generate 12,000 samples. Five different ML models involving artificial neural networks (ANN) are built in Python. Statistical results showed that train and test scores achieved promising outcomes in all ML models. However, when predicting user-defined scenarios not involved in the generated dataset, only ANNs perform generalizable, accurate predictions. The paper discusses the ability of ANN models to accurately predict different design scenarios and locations, and the trustworthiness of the training and test scores based only on collected data. © 2025, Education and research in Computer Aided Architectural Design in Europe. All rights reserved.Conference Object Developing Machine Learning Models to Predict Outdoor Thermal Comfort of Kinetic Shading Devices: An Approach for Global Optimization(Education and Research in Computer Aided Architectural Design in Europe, 2025) Dağlier, Y.; Ekici, B.; Korkmaz, K.Utilizing artificial intelligence (AI) methods in the design process supports the achievement of sustainable alternatives during the conceptual design. In various AI methods, optimization and machine learning (ML) algorithms are the most common methods to develop predictive models and discover favorable design alternatives with significantly reduced computational time. Recent works focused on limited datasets, as well as the evaluation of the developed prediction models based on collected data. During the optimization process of complex design problems, the number of design parameters becomes enormous; thus, search areas contain many design alternatives that might lead the search outside of the collected data. Therefore, evaluating the accuracy of prediction models only based on the collected samples may result in scenarios where the predicted outcome during the optimization process aligns with an unrealistic solution. This study investigates how accurately prediction models developed using different ML algorithms can perform in optimization processes. The proposed framework is used to cope with outdoor thermal performance, considering kinetic shading devices with rigid origami techniques. A parametric shading device model with kinematic principles and 10 design parameters is created in Grasshopper 3d. LadyBug is used to analyze the performance of the universal thermal climate index (UTCI). To minimize the UTCI, the radial basis function optimization (RBFOpt) algorithm in the Opossum plugin is used. To compare the optimization results with the prediction results, multiple linear regression, support vector machines, random forest, polynomial regression algorithms, and artificial neural networks (ANN) are developed to predict outdoor thermal comfort performance targets on each collected data set with 2000 samples. Results showed that ANN models can provide more accurate predictions during the optimization process. The paper aims to discuss the way ML algorithms are applied and evaluated for ML-based optimization domains in design problems. © 2025, Education and research in Computer Aided Architectural Design in Europe. All rights reserved.Article A Machine Learning Framework for Advanced Analytical Detection of CD36 Using Immunosensors Below Limit of Detection(Elsevier Ltd, 2026) Yeke, M.C.; Gelen, S.S.; Fil, H.; Yalcin, M.M.; Gumus, A.; Yazgan, I.; Odaci, D.We introduce a machine learning (ML)-based regression framework for quantitative electrochemical analysis, representing a paradigm shift from traditional univariate methods to a multivariate approach. Conventional analysis is constrained by reducing the entire signal to a single peak current feature to define a linear range and calculate a limit of detection (LOD). In contrast, our methodology treats the Differential Pulse Voltammetry (DPV) curve as time-series data, creating a high-dimensional fingerprint by systematically evaluating multiple data windows with varying widths around the main signal peak to identify the most informative segment. To validate this approach, a biosensor was developed by immobilizing Anti-CD36 antibodies on polydopamine-modified screen-printed carbon electrodes for the detection of CD36, a key protein in metabolism and immunity. Measurements were collected across 12 concentrations, including blank samples, spanning a range of 0 to 25 ng/mL. Following data augmentation, nine different regression models were evaluated, with the top-performing models achieving near-perfect prediction accuracy (R2>0.99) across this entire range. This high accuracy across the full concentration spectrum quantitatively demonstrates the method's ability to operate without relying on traditional concepts like linear range or LOD, enabling reliable detection at ultra-low levels. Furthermore, the immunosensor exhibited high selectivity against common interferents and excellent recovery in human serum. This methodology represents a significant advancement in analytical electrochemistry, providing a transferable approach for enhancing sensitivity in biomarker detection with potential applications in clinical diagnostics and biomedical research. The codes and dataset are made publicly available on GitHub to support further research: https://github.com/miralab-ai/biosensors-AI. © 2026 The Author(s)Conference Object Machine Learning-Based Antenna Selection and Secrecy Capacity Analysis(Institute of Electrical and Electronics Engineers Inc., 2025) Erdurak, Burak; Erdoǧan, Eylem; Gürkan, FilizThe performance of machine learning methods was analyzed to optimize antenna selection in wireless communication systems, and system's secrecy performance was observed. To enhance the antenna selection process, Deep Neural Networks (DNNs), Convolutional Neural Networks (CNNs), and the KNearest Neighbors (KNN) algorithm were utilized. Channel vectors were used as model inputs, aiming to select the most optimal transmission path among N possible candidates. During the training phase, the antenna with the highest Signal-to-Noise Ratio (SNR) was selected for data labeling. The performance of Single-Input Multiple-Output (SIMO), Multiple-Input SingleOutput (MISO), and Multiple-Input Multiple-Output (MIMO) system architectures was evaluated using model accuracy and the F1-score. Additionally, the secrecy capacity corresponding to the selected antennas was computed, demonstrating the feasibility of secure communication. The results indicate that deep learningbased methods achieved higher accuracy, with the CNN model emerging as the most successful approach, reaching an accuracy of over 95% across all system configurations. © 2025 Elsevier B.V., All rights reserved.Article Integrating QSAR Analysis and Machine Learning To Explore the Antidiabetic Potential of Natural Compounds(AMG Transcend Association, 2025) Sincar, B.; Yalcin, D.; Bayraktar, O.This study explores the antidiabetic potential of 72 natural compounds using molecular descriptors and QSAR modeling combined with machine learning techniques. The dataset includes 11 experimentally obtained compounds and 61 from the literature, characterized by their IC50 values indicating 50% inhibition of α-glucosidase enzyme activity. Molecular descriptors were generated using ChemAxon’s MarvinSketch and PADEL software, narrowing down over 3000 descriptors to 23 relevant features. Statistical analysis revealed significant multicollinearity among variables, necessitating the application of non-linear machine learning models, namely Random Forest and Gradient Boosting. These models demonstrated predictive capabilities with R² values of 0.7751 and 0.8066, respectively, and highlighted molecular weight and the number of heteroatoms in ring structures as critical features influencing IC50 values. Despite the dataset's variability and limited size, the study underscores the potential of integrating QSAR and machine learning approaches to effectively predict the antidiabetic activity of natural compounds. The findings provide valuable insights for advancing computational methods in drug discovery. © 2025 by the authors.Conference Object Citation - WoS: 1Konteyner Görüntülerini Kullanarak Hasar Tespiti ve Sınıflandırması(IEEE, 2020) Imamoglu, Zeynep Ekici; Tuglular, Tugkan; Bastanlar, YalinIn the logistics sector, digital transformation is of great importance in terms of competition. In the present case, container warehouse entry / exit operations are carried out manually by the logistics personnel including container damage detection. During container warehouse entry / exit process, the process of detecting damaged containers is carried out by the personnel and several minutes are required to upload to the IT system. The aim of our work is to automate the detection of damaged containers. This way, the mistakes made by the personnel will be eliminated and the process will be accelerated. In this work, we propose to use a convolutional neural network (CNN) that takes the container images and classify them as damaged or undamaged. We modeled the problem as a binary classification and employed different CNN models. The result we obtained shows that there is no single best method for the classification. It is shown how the dataset was created and how the parameters used in the layered structures affect the models employed in this study.Conference Object Citation - WoS: 3Citation - Scopus: 8Distinguishing Between Microrna Targets From Diverse Species Using Sequence Motifs and K-Mers(SCITEPRESS, 2017) Yousef, Malik; Khalifa, Waleed; Acar, İlhan Erkin; Allmer, JensA disease phenotype is often due to dysregulation of gene expression. Post-translational regulation of protein abundance by microRNAs (miRNAs) is, therefore, of high importance in, for example, cancer studies. MicroRNAs provide a complementary sequence to their target messenger RNA (mRNA) as part of a complex molecular machinery. Known miRNAs and targets are listed in miRTarBase for a variety of organisms. The experimental detection of such pairs is convoluted and, therefore, their computational detection is desired which is complicated by missing negative data. For machine learning, many features for parameterization of the miRNA targets are available and k-mers and sequence motifs have previously been used. Unrelated organisms like intracellular pathogens and their hosts may communicate via miRNAs and, therefore, we investigated whether miRNA targets from one species can be differentiated from miRNA targets of another. To achieve this end, we employed target information of one species as positive and the other as negative training and testing data. Models of species with higher evolutionary distance generally achieved better results of up to 97% average accuracy (mouse versus Caenorhabditis elegans) while more closely related species did not lead to successful models (human versus mouse; 60%). In the future, when more targeting data becomes available, models can be established which will be able to more precisely determine miRNA targets in hostpathogen systems using this approach.