Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
Browse
5 results
Search Results
Now showing 1 - 5 of 5
Article Citation - WoS: 1Citation - Scopus: 1Airborne and Dust-Bound PBDEs Indoors and Outdoors in Izmir, Türkiye: A Multi-Route Exposure - Risk Assessment(Elsevier Sci Ltd, 2025) Genisoglu, Mesut; Edebali, Ozge; Sofuoglu, Aysun; Turgut, Cafer; Sofuoglu, Sait C.Phased-out flame retardants, e.g., polybrominated diphenyl ethers (PBDEs), persist in environmental media due to their resistance to degradation and ongoing emissions from PBDE containing materials and industrial activities. This study addresses a notable data gap in a unique setting, i.e., & Idot;zmir, T & uuml;rkiye, by investigating PBDE levels at homes, schools, and caf & eacute;/bar/restaurants, and assessing exposure and associated health risks. Indoor and outdoor air and dust samples were collected from rural, suburban, and urban areas. Exposure through ingestion, dermal absorption, and inhalation routes, and associated chronic-toxic and carcinogenic risks were estimated with Monte Carlo Simulation. Despite having been phase-out, house-dust Sigma BDE concentrations remained prevalent with average levels of >2000 ng/g in schools and homes, while outdoors they were <500 ng/g. BDE-209 was the predominant congener with an indoor air concentration of 486 pg/m(3) in schools and 56.7 pg/m(3) in homes. BDE-209 contributed 83.5-90.4 % of the indoor air Sigma BDE concentration in schools, while in homes this contribution ranged from 70.8 to 75.8 %. Aggregate exposure estimates show the predominant PBDE congener, BDE-209, was primarily exposed by accidental ingestion (58.6 %) followed by dermal absorption (21.9 %) and inhalation (19.5 %). Chronic-toxic risk (CTR, for BDE-47, BDE-99, BDE-153, and BDE-209) and carcinogenic risk (CR, for BDE-209) for the ingestion and dermal absorption routes indicated that house-dust and indoor-air PBDE exposures are not found to be considerable for human health. However, the contribution of inhalation route to the aggregate exposure of BDE-28, BDE-47, BDE-100, BDE-99 (87.0 %, 60.5 %, 54.3 %, and 57.3 %, respectively) may indicate the evermore PBDE exposure by inhalation for lower brominated congeners as they become more significant through environmental debromination of the predominant BDE-209.Article Enhanced Catalytic Performance of Rhizomucor Miehei Lipase on Di-N and Diethylhexyl Phthalates: Insights Into Substrate Specificity and Immobilization Strategy(Taylor & Francis Ltd, 2025) Balci, Esin; Rosales, Emilio; Curras, Marta Pazos; Sofuoglu, Aysun; Sanroman, M. A.Di-n-butyl (DnBP) and Diethylhexyl Phthalates (DEHP), known as potential endocrine disruptors, are priority pollutants categorized by many regulatory agencies. Enzymatic degradation is a green and efficient approach to remove PEs in the environment. In this study, the DnBP and DEHP degradation performance of Rhizomucor miehei lipase (palatase) in free and immobilized forms on Halloysite nanoclays (HNCs) in an aqueous system was investigated. Upon enzyme immobilization, the alterations in the palatase's secondary structure were examined using the circular dichroism (CD) analysis. The binding affinity of DnBP and DEHP to palatase was evaluated with molecular docking approaches. The enzyme's immobilization efficiency and relative activity were found to be 80.3% and 87.8%, respectively. CD results revealed that palatase retained its secondary structure to a significant extent. HNCs-palatase (HNCs-P) exhibited a high stability, as the structural integrity of palatase was mostly preserved. Both free palatase (FP) and HNCs-P fully degraded DnBP and DEHP (100 mg/L) to phthalic acid and a degradation pathway of DnBP and DEHP was suggested. Immobilization prevented the enzyme inhibition caused by the accumulation of metabolites. After seven consecutive uses, HNCs-P was still able to degrade DnBP (63.3%) and DEHP (72.8%). Molecular docking results showed that DEHP had a higher affinity for palatase than DnBP. This study suggests that enzyme immobilization onto HNCs can increase their stability and catalytic performance. FP and HNCs-P effectively hydrolyse ester bonds responsible for phthalate toxicity. Considering their high efficiency, FP and HNCs-P can be used as potential phthalate degraders in various environmental remediation processes.Article Citation - WoS: 6Citation - Scopus: 9The Effect of Military Conflict Zone in the Middle East on Atmospheric Persistent Organic Pollutant Contamination in Its North(Elsevier, 2023) Ayrı, İlknur; Genişoğlu, Mesut; Sofuoğlu, Aysun; Kurt Karakuş, Perihan B.; Birgül, Askın; Sofuoğlu, Sait CemilThis study aimed to investigate long-range atmospheric transport of selected POPs released due to the effects of mili-tary conflicts in regions to the south of Turkey's borders. Ten locations were selected to deploy passive air samplers at varying distances to the border on a southeast-west transect of the country, proximity-grouped as close, middle, and far. Sampling campaign included winter and transition months when desert dust transport events occur. Hypothesis of the study was that a decreasing trend would be observed with increasing distance to the border. Group comparisons based on statistical testing showed that PBDE-183, E45PCB, and dieldrin in winter; PBDE-28, PBDE-99, PBDE-154, p,p '-DDE, E14PBDE, and E25OCP in the transition period; and PBDE-28, PBDE-85, PBDE-99, PBDE-154, PBDE-190, PCB-52, E45PCB, p,p '-DDE, and E25OCP over the whole campaign had a decreasing trend on the transect. An analysis of concen-tration ratio to the background showed that long-range atmospheric transport impacted the study sites, especially those of close group in comparison to the local sources. Back-trajectory analyses indicated that there was transport from the conflict areas to sites in the close-proximity group, while farther sampling locations mostly received air masses from Europe, Russia, and former Soviet Union countries, followed by North Africa, rather than the military con-flict areas. In consequence, decrease in concentrations with distance and its relation to molecular weight through pro-portions, diagnostic ratios, analysis of concentration ratio to the background, and back-trajectory analyses support the effect of transport from the military-conflict area to its north.Book Part The Role of Polyurethane Foam Indoors in the Fate of Flame Retardants and Other Semivolatile Organic Compounds(American Chemical Society, 2021) Genişoğlu, Mesut; Sofuoğlu, Sait Cemil; Sofuoğlu, AysunFlame retardant chemicals are added to polyurethane foams (PUFs) during production. These chemicals are released to the environment during the use of PUF containing furniture or building materials. In contrast, organic pollutants such as polychlorinated biphenyls, polycyclic aromatic hydrocarbons, synthetic musk compounds, and volatile organic compounds could be sorbed by PUF depending on the concentration gradient, ambient temperature, and the physicochemical properties. Most of these substances tend to accumulate by adhering to organic matter in dust, particles, and surfaces, as they do not degrade for long periods of time. Sorption-emission cycles of PUF-associated organic compounds prolong their presence in indoor environments, which could increase human exposure. Since these organic compounds might have carcinogenic or chronic-toxic health effects on living organisms, it is important to understand the role of PUF in exposure to these substances in indoor environments. This chapter reviews the literature on the relationship of organic substances with PUF in indoor environments.Article Citation - WoS: 20Citation - Scopus: 21Long Term Stability of Biodegradable Polymers on Building Limestone(Elsevier Ltd., 2019) Kaplan, Zişan; Böke, Hasan; Sofuoğlu, Aysun; İpekoğlu, BaşakSynthetic polymers can be replaced by biodegradable ones as adhesives, water repellents and consolidants on the stone surfaces and facades of the historic buildings in their conservation to minimize future deterioration. In this study, the long-term stability of two biodegradable polymers, polyhydroxybutyrate (PHB) and poly-L-lactide (PLA), and an acrylic polymer (Paraloid B72) which is commonly used in conservation works of artefacts, were evaluated on limestone using a UV lamp-weathering chamber (up to 104 days) for future protection studies. Chemical and morphological changes induced by an accelerated weathering test were examined by Fourier Transform Infrared spectroscopy (FT-IR) and Scanning Electron Microscopy (SEM) analyses. Protection efficiency of the polymers was determined by the changes in color, capillary water absorption, static contact angle on limestone. Paraloid B72, PHB, and PLA coatings significantly increased hydrophobicity while decreasing capillarity water absorption and caused negligible change in the color of the limestone. Protection efficiencies of PLA and PHB polymers were almost the same as that of Paraloid B72, a widely used acrylic polymer. However, PLA and PHB seemed to be favorable polymers as protective agents due to their reversibility and biodegradability, low chromatic changes, good hydrophobic behavior and good stability to weathering in reducing the effects of outdoor exposure on limestone surfaces.