Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection

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  • Article
    A Multidimensional Comparative Analysis of Human Expert vs. AI-Driven Feedback Approaches on Learner-Centered and Collaborative Groups
    (Routledge, 2026) Yıldız Durak, H.; Onan, A.
    The aim of this study is to examine the multidimensional effects of AI-based feedback in learner-centered and collaborative learning environments among university students. The study employed a five-group experimental design: two individual learning groups receiving either AI-based feedback(G1) or human expert feedback(G2), two collaborative learning groups receiving either AI(G3) or human expert feedback(G4), and control group(G5). According to the research results, G4 showed the highest level of development in the areas of creative problem solving, internal-external motivation, and critical thinking. G1 was the group with the highest performance, particularly in terms of system interaction, completed activities, and assignments. In contrast, G2 showed the lowest results in terms of both cognitive development and learning analytics. AI-based feedback in collaborative learning environments provided the highest development in cognitive skills, while AI-based in individual work was more effective in increasing system participation. Factorial MANCOVA indicated significant interactions between learning environment and feedback type on posttest outcomes, with strongest effects on self-efficacy, intrinsic motivation, and flexibility. These results show that AI-based feedback has different effects in both individual and collaborative learning contexts. Qualitative thematic analysis highlighted themes of cognitive facilitation, creativity enhancement, feedback quality perceptions, and environment preferences. © 2026 Informa UK Limited, trading as Taylor & Francis Group.
  • Article
    On Group Connected Transmissive Beyond Diagonal RIS for MIMO Systems
    (Institute of Electrical and Electronics Engineers Inc., 2026) Ilguy, M.; Özbek, B.; Le Ruyet, D.
    Reconfigurable intelligent surfaces (RIS) have emerged as an important technology for next-generation wireless networks by intelligently manipulating the wireless propagation environment. Beyond Diagonal RIS (BD-RIS) extends the traditional RIS architecture by allowing non-diagonal reflection matrices, enabling more flexible signal manipulation. Transmissive RIS (T-RIS), on the other hand, facilitates the transmission of signals through the metasurfaces. In this paper, we propose a novel design called transmissive BD-RIS (T-BD-RIS), which integrates the functionalities of BD-RIS and T-RIS to enhance the user data rate. We design an algorithm for the group connected (GC) configuration, which jointly optimizes the beamforming at the base station, the T-BD-RIS transmission matrix, and the receive combiner at the user side. The fully connected (FC) and single connected (SC) cases are special instances of the proposed generic GC design, obtained by an appropriate choice of the number of groups. We evaluate the performance of various schemes, demonstrating the potential of the proposed approach. © 1997-2012 IEEE.
  • Article
    FTIR Spectroscopy Coupled With Chemometrics for Evaluating Functional Food Efficacy in an in Vitro Model of Iron Deficiency Anemia
    (Elsevier Science Ltd, 2026) Dalyan, Eda; Cavdaroglu, Cagri; Ozen, Banu; Gulec, Sukru
    Vibrational spectroscopy offers a rapid, cost-effective approach for studying biological systems. This study employs Fourier Transform Infrared (FTIR) spectroscopy, combined with Soft Independent Modeling of Class Analogy (SIMCA), to evaluate treatment outcomes for iron deficiency anemia (IDA). The model was built using spectra from healthy and anemic cells, then validated with cells treated with commonly used iron supplements. In calibration, 9 of 10 control and all IDA samples were correctly classified; 14 of 15 validation samples were identified as healthy. The model was applied to cells treated with protein-iron complexes. All samples treated with a 60:1 protein-iron ratio matched the healthy group, while 3 of 4 treated with a 10:1 ratio matched the IDA group. These results were further supported by iron-regulated gene expression of transferrin receptor (TFR) and (Ankyrin Repeat Domain 37) ANKRD37. FTIR coupled with chemometrics enables rapid assessment of functional effects and shows potential for screening functional ingredients in anemia-targeted food products.
  • Article
    Application of 3D Cell Culture Techniques in Nanotoxicology: How Far Are We
    (Springer, 2026) Shakeri, Raheleh; Mirjalili, Seyedeh Zohreh; Karakus, Ceyda Oksel; Safavi, Maliheh
    Investigation of toxicological profile and possible side effects of engineered nanomaterials (ENMs) is of high importance. Historically, two-dimensional (2D) cell culture was used to study the toxicity of the ENMs, but due to their inability to simulate in vivo cell behavior, three-dimensional (3D) cell culture systems have been developed. Nanotoxicity studies initiate with in vitro experiments and continue with in vivo studies, which are very challenging and sometimes accompanied by conflicting data due to the in vitro-in vivo gap. Thus, scientists are turning their attention to microfabrication techniques and engineered systems "called organ-on-a-chips", which act as an intermediate between in vivo and in vitro systems. The present account tries to review the classical study models and suitably cover the emerging 3D culture models including scaffold-free and scaffold-based 3D cell cultures, 3D co-culture with direct contact and without cell-cell contact methods as well as microfluidic-based tissue chips and organoids. Overall, this review aims to give readers a better insight about the ENMs' toxicology and fill the gaps between the knowledge and practical techniques. Hopefully, the presented information will resolve the issues of 2D in vitro cultures and display the clinically relevant responses to the concerns of therapeutic ENMs.
  • Article
    Sustainable Recovery of Critical Raw Materials From Geothermal Igneous Systems: Geochemical, Mineralogical, and Techno-Economic Insights from the Dikili-Bergama Field (Western Anatolia, Turkiye)
    (Elsevier, 2026) Ayzit, Tolga; Baba, Alper
    The sustainable co-extraction of critical raw materials (CRMs) with renewable geothermal energy offers a dual pathway to support the circular economy and low-carbon transition. In this study, an integrated geochemical and mineralogical approach is used to comprehensively assess the recoverable lithium (Li) boron (B), strontium (Sr) and other critical raw materials in the geothermal reservoirs of the Dikili-Bergama region Turkiye. A geochemical analysis was carried out by systematic sampling and multi-element testing of geothermal water and reservoir rock. Hydrogeochemical studies of the geothermal fluids indicated the presence of remarkable concentrations of B (4.6 ppm), Sr (2.8 ppm) and Li (1.2 ppm), suggesting the possibility of active leaching processes in the deposit. Mineralogical studies using X-ray diffraction (XRD) have revealed a number of secondary mineral phases, such as quartz and labradorite, indicating the interaction between water and rock. These interactions affect not only the permeability and porosity of the deposit, but also the mobilization and precipitation of CRMs. A techno-economic analysis will be used to identify potential synergies that could improve the economic feasibility of geothermal projects in the region. The Monte Carlo simulation has shown that the Dikili-Bergama geothermal reservoirs have a potential of similar to 712 tons of Li. In this study, the CRM potential that emerged during the geothermal energy exploitation process in the region was calculated. The temporality and the process of obtaining are completely related to the extraction technology. This offers the dual benefit of renewable energy and strategic mineral extraction, contributing to sustainable resource management in volcanic environments.
  • Article
    The Effect of Layered Cover Plate Material on the Ballistic Performance of Ceramic Armors: Experimental and Numerical Study
    (Pergamon-Elsevier Science Ltd, 2026) Cellek, Seven Burcin; Tasdemirci, Alper; Cimen, Gulden; Yildiztekin, Faki Murat; Toksoy, Ahmet Kaan; Guden, Mustafa
    This study investigates the ballistic performance of silicon carbide (SiC) ceramic armor systems reinforced with single and hybrid metallic cover plates composed of Ti-6Al-4V (Ti64) and copper. Controlled ballistic experiments combined with validated LS-DYNA simulations were conducted to examine how cover-plate material, thickness, and stacking sequence influence penetration resistance, energy dissipation, and failure mechanisms. The experimental results revealed that metallic cover plates significantly enhance protection by improving projectile erosion and extending dwell time. While both Ti64 and copper single layers increased the antipenetration capability (APC) compared with bare SiC, hybrid configurations achieved the highest performance. The optimal design, consisting of a 2 mm Ti64 plate placed in front of a 1 mm copper plate, produced the greatest reduction in penetration depth and the highest APC value. Numerical analyses closely replicated the experimental trends and provided insight into stress-wave interactions, pressure evolution, and damage progression within the ceramic. The findings demonstrate that hybrid Ti64-Cu systems not only improve initial impact resistance but also redistribute energy toward the front layers, reducing stress transmission to the backing and mitigating catastrophic ceramic failure. The combined experimental and numerical results establish a clear design framework for developing lightweight, high-efficiency ceramic armor through tailored hybrid layering strategies.
  • Article
    Fractionation of Guaiacyl and Syringyl-Lignin Units Using Organic Solvent Nanofiltration
    (Elsevier, 2026) Croes, Tim; Dutta, Abhishek; Van Aelst, Korneel; Sels, Bert; Van der Bruggen, Bart; Cornet, Iris
    A major obstacle to employing the full potential of lignin-based aromatics is the fractionation of the monomers present in lignin, specifically the separation of guaiacyl (G) and syringyl (S) units, which possess nearly identical molecular weights (196 Da versus 166 Da) and dimensions, and identical functional groups. Such similarities make their separation highly challenging using conventional techniques and are generally considered beyond the capabilities of size-based membrane processes. This study examines the feasibility of organic solvent nano-filtration for fractionation of guaiacyl and syringyl units, and how membrane and process parameters affect separation of these two molecules. Sixteen commercially available membranes were tested with methanol and ethyl acetate as solvents. The results demonstrate that, despite the extreme similarity of the solutes, selective separation is achievable and is primarily governed by membrane material and solvent selection rather than the pore size-based molecular weight cut-off. Polyimide-based solvent-resistant membranes exhibited the highest selectivity, with a maximum observed separation factor of 3.33 obtained using a DuraMemTM 500 membrane in methanol. These findings demonstrate the potential of nanofiltration to address previously unresolved separation challenges in lignin valorization and provide a basis for further process development.
  • Article
    Damage Assessment of Structures Following the February 6, 2023 Kahramanmaraş Earthquakes: A Dataset-Based Case Study in Gaziantep, Türkiye
    (Springer Heidelberg, 2025) Atasever, Kurtulus; Aydogdu, Hasan Huseyin; Narlitepe, Furkan; Goksu, Caglar; Demir, Ugur; Demir, Cem; Ilki, Alper
    Following the 2023 Kahramanmara & scedil; Earthquakes (Mw 7.7 and 7.6) that struck T & uuml;rkiye on February 6, 2023, the Ministry of Environment, Urbanization, and Climate Change (MoEUCC) initiated a large-scale post-earthquake damage assessment campaign, targeting more than 2,3 million structures within the affected region. A comprehensive field survey was carried out in and around Gaziantep, one of the most severely affected cities. The authors assessed more than 1700 structures representing a wide range of occupancy types, including residential, educational, healthcare, religious, administrative, industrial, and lodging structures. In this paper, the methodological process of post-earthquake data collection in and around Gaziantep is presented, together with the data on the distribution of damage with respect to construction period, number of stories, and building occupancy type, to ensure a complete understanding of the extent and characteristics of structural damage. The damage assessment employed two data sources: (i) the data gathered through the authors' newly developed, novel damage-assessment software, presented here for the first time, and (ii) the official post-earthquake damage database of the MoEUCC. A further novelty of this study is the presentation of the largest dataset to date for the investigated earthquake doublet, encompassing approximately 1700 buildings. Additionally, the relationship between damage states, peak ground accelerations, and fault distances is thoroughly investigated. The detailed earthquake-hit site investigations revealed that the examined structures displayed structural inadequacies akin to those witnessed in previous seismic events, with a notable focus on the arrangement of the structural system, the quality of construction materials and reinforcement detailing.
  • Article
    Ormosil Hybrid Coatings as a Sustainable Antibiofouling Solution for Microalgae Cultivation in Tubular Photobioreactors
    (Elsevier Sci Ltd, 2026) Belen, Sema Nur; Ipsalali, Ozde; Gunes, Kaniye; Kucuker, Mehmet Ali; Cengiz, Ugur
    This study demonstrated the potential of citric acid-APTES (Ormosil) coatings as an effective antifouling strategy to reduce biofilm formation in tubular photobioreactors used for microalgae cultivation. Among the tested coatings, CApTES2.7 exhibited superhydrophilic behavior in air and superoleophobic behavior underwater, significantly reducing the adhesion of Chlorella vulgaris compared to uncoated glass surfaces. Light transmission experiments and microscopic analyses showed that biofilm accumulation on coated surfaces decreased by more than 50 %, maintaining optical clarity within the reactor. Thermodynamic, DLVO, and XDLVO modeling supported these findings, indicating lower adhesion energies for algal cells on Ormosil-coated surfaces, consistent with their experimental antifouling performance. The application of CApTES2.7 coating in tubular PBR systems resulted in a 54.5 % increase in light transmittance compared to uncoated systems, thereby improving the photonic environment available for microalgal growth. Additionally, no chemical cleaning was required between cultivation cycles in coated reactors, demonstrating potential for reducing operational costs and water consumption in large-scale systems. In conclusion, this study presents an environmentally friendly and sustainable approach to overcoming biofilm-induced light attenuation-one of the main bottlenecks in industrial photobioreactors. Ormosil-based coatings not only extend the service life of PBRs but also enhance the economic feasibility of microalgae-based bioprocesses for biofuel, bioplastics, and high-value biomolecule production.
  • Article
    Chloroaluminum Phthalocyanine Loaded Bovine Serum Albumin Nanoparticles as a Dual-Functional Nanoplatform for Sono-Photodynamic Cancer Therapy
    (Elsevier, 2026) Akyol-Karpuzcu, Cansu; Nartas, Eylem Doga; Calibasi-Kocal, Gizem; Akdogan, Yasar
    Chloroaluminum phthalocyanine (ClAlPc) loaded bovine serum albumin (BSA) nanoparticles (NPs) were synthesized as a dual-functional platform for photodynamic and sonodynamic therapies (PDT and SDT). ClAlPc loading did not disturb the morphology of the BSA NPs. Their spherical structure, with a size around 200 nm, was preserved upon ClAlPc loading (1 %w/w). Singlet oxygen productions in the presence of ClAlPc loaded BSA NPs or free ClAlPc were determined by ultraviolet absorption (UV-vis) spectroscopy and electron paramagnetic resonance (EPR) spectroscopy. While a slower rate of singlet oxygen formation rate after both PDT and SDT was detected by UV-vis measurements in the presence of ClAlPc loaded BSA NPs, EPR results showed a similar rate of singlet oxygen formation for both ClAlPc loaded BSA NPs and free ClAlPc. Confocal microscopy confirmed the efficient cellular uptake and perinuclear localization of the ClAlPc loaded BSA NPs in HCT-116 cancer cells. In vitro cytotoxicity studies demonstrated a dose and time dependent photo-and sonotoxic effects in the presence of ClAlPc loaded BSA. In particular, simultaneous application of light and ultrasound as sono-photodynamic therapy (SPDT) resulted in 15 % cell viability in the presence of ClAlPc loaded BSA NPs, which is much lower than individual PDT and SDT results, confirming the effect of the combination therapy on cell viability. In comparison, free ClAlPc reduced cell viability to 27 %. These findings suggest that ClAlPc loaded BSA NPs is a promising "one-for-two" nanoplatform for combined cancer therapy to reduce the limitations of both methods.