Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
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Article Geothermal Resources of Azerbaijan: A Comprehensive GIS-Based Remapping and Temperature Assessment Review(State Oil Company of Azerbaijan Republic, Oil Gas Scientific Research Project Institute, 2025) Isgandarov, S. M.; Uzelli, T. T.; Mukhtarov, A. N.; Baba, A. S.Azerbaijan has considerable geothermal energy potential. The resources are concentrated in regions such as the Absheron Peninsula, the Greater and Lesser Caucasus, the Kur Basin, and the Pre-Caspian-Guba region. Although the country does not have active volcanoes and geysers, geothermal energy can be extracted from deep wells, abandoned hydrocarbon fields, and natural hot springs. This study analyzes and maps Azerbaijan's geothermal resources using a Geographic Information System (GIS) to assess their potential for power generation and direct use. The main results show that wells such as Jarly-3 field thermal fluids with temperatures of up to 96 degrees C. Other promising sites include Daridagh in Nakhchivan and the Shikh field in Absheron, where geothermal water with a temperature of 68 degrees C. GIS-based interpolation techniques, including Kriging and Empirical Bayesian Kriging were applied to model the subsurface temperature distributions and identify regions with the highest geothermal potential. The study analyzed data from over 500 hot springs and geothermal wells to determine temperature variations at different depths. The results indicate that Azerbaijan's geothermal resources could support applications ranging from electricity generation to heating, agriculture, and industrial processes. Developing these resources could diversify Azerbaijan's energy sector and reduce dependence on fossil fuels. This study highlights the need for further exploration, improved drilling technologies, and investment in geothermal infrastructure to unlock the full potential of Azerbaijan's geothermal reserves.Article The Spatial Patterns of Regional Employment in Europe as a Measure of Economic Resilience in Recession Periods(Center for European Regional and Local Studies of the University of Warsaw (EUROREG), 2025) Değerli Çifçi, B.; Duran, H.E.Empirical literature in the field of regional resilience has most commonly concentrated on a unique economic shock. However, the existing studies have fallen short of comparing the resilience patterns across different crises. The purpose of this study is to investigate the geographical persistence of regional resilience across different recessionary shocks, namely: 1) the 2008–2010 Global Financial Crisis; 2) the 2011–2013 Sovereign Debt Crisis; 3) the 2019–2020 COVID-19 pandemic. The study covers 202 European Nuts II regions. It applied a range of empirical tools such as Markovian Transition Probability Matrices, Global Moran’s and Local Moran’s, Kolmogorov-Smirnov tests, Kendal’s tau, and Spearman’s correlation coefficient, as well as illustrative maps. As an outcome, several important conclusions are reached. First, the spatial pattern of resilience is not stable/persistent over time, as the three recessions tend to hit different places at different crisis times. Second, in general, Southern European regions are the most consistently fragile/vulnerable regions. Third, spatial patterns of resilience are weakly correlated across the different recessions. From the policy standpoint, it is understood that dealing with employment resilience is more difficult than previously thought by the policymakers. Since the resilience pattern is not stable spatially, each crisis should be evaluated separately and no generic policy rules can be formulated to foster the resilience. Thus, one can understand that although the sources of the crises are different, there may be some geographies that are structurally suffering the recessions which necessitate a consideration of the reasons and the formulation of the related policies. © Authors 2025.Article Comparative Optimization of Hot Water and Citric Acid Extraction Methods for Sericin Recovery From Silk Cocoons: In Vitro Antioxidant and Antidiabetic Activities(Springer, 2026) Sincar, Bahar; Ozdemir, Feyza; Bicakci, Beyza Tutku; Erdem, Cansu; Yalcin, Dilek; Alamri, Abdulhakeem S.; Bayraktar, OguzSilk sericin, a hydrophilic protein derived from Bombyx mori cocoons, has attracted increasing interest due to its antioxidant, moisturizing, and enzyme-inhibitory properties. Efficient extraction is essential to preserve its biofunctional potential. In this study, sericin was extracted using hot water and 1.25% (w/v) citric acid using autoclave-based heating to achieve pressurized conditions above 100 degrees C. A Box-Behnken Response Surface Methodology (RSM) was applied to systematically evaluate the effects of extraction parameters (temperature and time) and to optimize five key response variables: yield, purity, molecular weight and polydispersity index (PDI), total antioxidant capacity (ABTS), and alpha-glucosidase inhibition activity. The results revealed that higher temperatures (125 degrees C) produced the maximum sericin yield, while moderate conditions (115 degrees C for 45 min) ensured better preservation of antioxidant and antidiabetic activities. Hot acid extraction resulted in significantly enhanced purity and enzymatic inhibition compared to hot water extraction. Sericin fractions above 7 kDa exhibited the strongest bioactivity, as reflected by lower IC50 values in both ABTS and alpha-glucosidase inhibition assays. The optimized hot water citric acid-based method yielded 24.00% sericin with 100.00% purity and an IC50 of 0.67 mg/mL for alpha-glucosidase inhibition. This study compares hot water and hot acid autoclave extractions using Box-Behnken design and evaluates their effects on sericin yield, purity, and bioactivities. Citric acid-based extraction produced higher purity and stronger alpha-glucosidase inhibition, while hot water extraction preserved antioxidant potential more effectively. These findings support the use of citric acid as an eco-friendly and scalable extraction agent and highlight the potential of sericin in biomedical and nutraceutical applications.Article Semi-Synthetic Sapogenin Derivatives Inhibit Inflammation-Induced Tumorigenic Signaling Alterations in Prostate Carcinogenesis(Elsevier Science Inc, 2026) Debelec-Butuner, Bilge; Ozturk, Mert Burak; Tag, Ozgur; Akgun, Ismail Hakki; Bedir, ErdalProstatic inflammation plays a pivotal role in prostate cancer development and progression via altering key cellular mechanisms, including proliferation, metastasis, and angiogenesis. Therefore, the use of antiinflammatory drugs could provide a valid contribution to PCa prevention and treatment. In our research, we explored semi-synthetic derivatives of cycloastragenol (CA) and astragenol (AG) to assess their potential to inhibit inflammation-mediated tumorigenic signaling. Building on our previous findings, which demonstrated their inhibitory activity on NFxB, we discovered that these molecules also suppress inflammation-induced cell proliferation and migration through distinct mechanisms. They effectively alleviated inflammation by reducing levels of ROS, NO, and VEGF expression. Furthermore, these molecules partially restored the expression of AR and the tumor suppressor NKX3.1, both of which are critical in prostate tumorigenesis within an inflammatory microenvironment. They also reversed inflammation-induced activation of Akt and (3-catenin signaling, suggesting their potential to inhibit inflammation-related prostate tumorigenesis. Our study further demonstrated that these molecules exhibited dose-dependent effects on inducing cell cycle arrest and apoptosis, as evidenced by increased p21 and decreased BCL-2 protein levels, leading to activated cell death and suppressed cellular migration. In conclusion, these semi-synthetic sapogenol derivatives demonstrate significant potential as antiinflammatory and anticancer agents, offering a promising approach for targeting prostatic inflammation and inflammation-driven prostate carcinogenesis.Article Improving Doppler Radar Performance through Optically-Reconfigurable Unequal Power Division with Semi-Analytical Approach(Taylor & Francis Ltd, 2025) Karatay, Anil; Atac, Enes; Dinleyici, Mehmet Salih; Yaman, FatihThe improvement of the signal-to-noise ratio (SNR) of Doppler radar systems, enabling the detection of targets at greater ranges even with limited power, has been a longstanding focus of research. However, while key limitations such as low target reflectivity and environmental interference are often addressed, the impact of efficient use of the input power remains an overlooked, yet crucial factor in overall sensitivity. Additionally, the power allocation needs to be examined from an analytical perspective for further enhancement. In this study, we present a novel measurement approach, utilizing both semi-analytical analysis and experimental methods, to improve the performance of a dual-antenna CW Doppler radar through the use of an optically reconfigurable unequal microwave power divider which provides well-directed power utilization. Comprehensive grid searches, supported by an analytical approach and considering various loss and noise scenarios, demonstrate the capability of the proposed reconfiguration method. In the Doppler radar experiments where the pendulum and servo motor were used as targets, an SNR increase of 3.04 and 2.11 dB in the radar signal was observed with the proposed method, respectively. This noticeable improvement in the SNR of the time-frequency plots indicates an enhancement in the measurement performance. The unequal power allocation enabled continuous detection of target motion with minimal signal loss, lowering the minimum detectable power level by more than 2 dB compared to the equal power division case. The experimental results show that integrating an optically reconfigurable microwave power divider into the Doppler radar system increases precision in velocity measurements.Article Rhythmanalysis of Istanbul Ayasofya's (re)mosquification During the COVID-19 Pandemic: A Diachronic Overview(Routledge Journals, Taylor & Francis Ltd, 2025) Akture, Zeynep; Kazanasmaz, Zehra TugceInauguration of the Grand Mosque of Ayasofya, Istanbul, in 2020 was among the cultural heritage-related magnet events of the COVID-19 pandemic period. This essay focuses on the impacts of function change on the monument's spatial experience, by tracing a continuity of change in its everyday life and use in a continuously changing urban context, through comparatively minor physical interventions starting with the 'necessary minimum' to its 'acupuncture points', as was done during its earlier mosquification and museumification, both of which (were) initiated (by) structural transformations in the longue dur & eacute;e. Following Henri Lefebvre's argument on spatiality of politics and history, and adopting his rhythmanalysis tool, significance of the recent function change is argued to reside in the resulting spatial experience that is characterised by spatiotemporally alternating and/or overlapping political, religious, and tourist 'rituals' that are conditioned by and conditioning longer-term structural changes. Concluding observations target future research along the proposed trajectory.Conference Object Measuring the Size of Change Requests in Microservice-Based Software Projects(Springer Science and Business Media Deutschland GmbH, 2026) Yenel, M.; Ünlu, H.; Demirors, O.Accurately estimating the effort required for implementing change requests remains a critical challenge in software engineering, especially in microservice-based software architectures (MSSA). Traditional functional size measurement methods often fail to capture the distinct characteristics of MSSAs. To address this limitation, we propose a change size measurement method based on MicroM, a size measurement approach specifically developed for MSSAs. The proposed method counts added, deleted, and modified events across functional, architectural, and algorithmic levels, and includes the number of affected initial requirements. We conducted an exploratory case study with 18 change requests and built four regression-based effort estimation models. The results show that combining event counts with the number of affected requirements improves estimation accuracy. Our method provides a more precise and context-aware way to estimate change-related effort in MSSA projects. © 2025 Elsevier B.V., All rights reserved.Article Enhancement of Corchorus Olitorius L. on Osteogenic Differentiation of MC3T3-E1 Pre-Osteoblast Cells by Increasing Alkaline Phosphatase and Hydroxyproline(Taylor & Francis Ltd, 2025) Ertugruloglu, Pinar; Baris, Elif; Okkali, Gaye Sumer; Boke Sarikahya, NazliCorchorus olitorius L. (jute mallow or molehiya) belongs to the Malvaceae family valued for its nutritional and medicinal properties. In this study, the potential to enhance osteogenesis in MC3T3-E1(Murine Calvaria-derived 3T3 Subclone E1) pre-osteoblastic cells was investigated to support bone formation and mineralisation. Leaf ethanolic extract was prepared and applied to MC3T3-E1 cells. Osteogenic effects were evaluated through three methods: MTT assays for cell viability, Alizarin Red S staining for calcium deposition, enzymatic analyses for alkaline phosphatase (ALP) and hydroxyproline (HYP). A non-cytotoxic concentration of C. olitorius extract (0.5 mg/mL) significantly increased ALP and HYP levels, promoting osteogenic differentiation in both undifferentiated and differentiated cells. HYP levels were notably elevated in differentiated cells. The findings suggested that C. olitorius extract may be a promising natural agent for enhancing bone health, warranting further in vivo and clinical studies to confirm its therapeutic potential.Article Benzoxazine-Linked Porous Organic Networks for Effective Iodine Capture(Royal Soc Chemistry, 2025) Canturk, Batu Sercan; Erdogmus, Mustafa; Gecalp, Yasmin; Sahin, Hasan; Buyukcakir, OnurThis study presents, for the first time, the investigation of a benzoxazine-linked porous organic network (BPON) for iodine capture. BPON was synthesized through the Mannich condensation of paraformaldehyde, melamine, and phloroglucinol. The porous structure and heteroatom-rich skeleton of BPON make it a promising adsorbent platform for iodine capture. BPON demonstrated an effective iodine capture capability in the vapour phase (3.32 g g-1) and an impressive uptake capacity in the aqueous phase (2.80 g g-1 capacity, 90.4% removal efficiency in 12 hours). To investigate the effect of curing on iodine capture, BPON was thermally cured to prepare thermally cured benzoxazine-linked porous organic networks (cBPONs) at three different temperatures: 200, 250, and 300 degrees C. cBPONs demonstrated an iodine capture capacity of up to 2.20 g g-1 and 1.67 g g-1 for vapour and aqueous phases, respectively. The iodine capture mechanism of BPON was investigated using various ex situ analyses, including Fourier transform infrared (FT-IR), Raman spectra, and X-ray photoelectron spectra (XPS). Structural analysis and theoretical calculations indicated the formation of a charge-transfer complex upon iodine capture, leading to the generation of polyiodide species. This study demonstrates the potential of BPONs for iodine capture and paves the way for developing new polymeric adsorbents for capturing iodine from air and water.Article The West Coast Geothermal Province: Insights from Geochemical and Geophysical Exploration for Green Hydrogen Development(Geological Society of India, 2025) Deshmukh, V.; Subba Rao, P.B.V.; Chandrasekharam, D.; Sathishkumar, S.; Srinivas, Y.; Chandrasekhar, V.The West Coast Geothermal Province (WCGP), located along India’s western margin, hosts 60 thermal springs with temperatures ranging from 33 to 70°C, classifying it as a low-enthalpy geothermal system. Geochemical analyses suggest that meteoric water percolates through granitic basement rocks, gaining heat from radioactive decay and geothermal gradients. Geophysical investigations have identified shallow geothermal reservoirs and fault/fracture zones that facilitate the upward movement of deep-seated hot water to the surface. Although traditionally overlooked for power generation, low-enthalpy geothermal systems are gaining attention due to technological advancements and the growing demand for sustainable energy solutions such as green hydrogen. Reservoirs with temperatures between 150 to 180°C have the potential to generate 3–5 MWe of off-grid electricity using thermoelectric generators, supporting applications like water desalination and hydrogen production. This study evaluates the potential of WCGP’s low-enthalpy geothermal resources for green hydrogen production, with a focus on both technical and economic aspects. Key technical parameters include reservoir temperature, power generation capacity, and system integration. Economic considerations encompass the Levelized Cost of Energy (LCOE), capital expenditures (CAPEX), operational expenditures (OPEX), and hydrogen production costs. By comparing geothermal hydrogen production with other energy sources, this research assesses its viability and competitiveness within the broader renewable energy landscape. © 2025 Elsevier B.V., All rights reserved.