Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection

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Access Right: Closed AccessSubject: search.filters.subject.Antibacterial activity

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  • Article
    Citation - WoS: 1
    Citation - Scopus: 1
    Enhanced Properties of Tio<sub>2</Sub> Nanotubes Through Α-fe<sub>2</Sub>o<sub>3< Surface Decoration: Synthesis, Characterization, and Performance Evaluation
    (Elsevier Sci Ltd, 2024) Doluel, Eyyup Can; Kartal, Ugur; Uzunbayir, Begum; Erol, Mustafa; Yurddaskal, Metin; Pulat, Gunnur; Guler, Saadet
    Electrochemical anodization, under a constant voltage of 45 V and for 15, 30, and 45 min, was performed to fabricate highly ordered TiO2 nanotubes. Depending on the processing paramters, the diameter of the TiO2 nanotubes was found to be around 95 +/- 6 nm, while the thickness of TNT layer exhibited a change with anodizing time, varying from 1 to 4 mu m. Subsequent to the anodization alpha-Fe2O3/TiO2 heterogeneous structure was created by the spin coating of iron precursor based solutions on TiO2 nanotubes. X-ray diffraction (XRD) and scanning electron microscopy (SEM) analysis were utilized to ascertain the phase structure and morphology of TiO2 nanotubes. The change of optical band gap values depending on the processing parameters was calculated using UV-Vis spectrophotometer data. The photocatalytic performances of the samples, namely the degradation rates and kinetics, were evaluated by examining the photodegradation of methylene blue (MB). The (TC15) sample, obtained by anodizing for 15 min and decorated with alpha-Fe2O3, exhibited the highest photocatalytic activity, with a degradation efficiency of 70 % at the end of 7 h of light exposure. On the other hand, the inhibition percentages of bacterial growth were examined and it was seen that the TC30 sample with the highest value was 88.89 % for E.coli bacteria and 70.57 % for S.aureus. To assess the mechanism of antimicrobial activity, ROS (Reactive Oxygen Species) Analysis were perfomed on T30 and TC30 groups and the ROS amount of TC30 was higher than T30. According to the results of the L929 mouse fibroblast cytotoxicity experiment with indirect contact according to ISO 10993-5 standards, all samples showed a successful performance in terms of cell viability. The cell viability of TC15 was higher in comparison to the control group.
  • Article
    Citation - WoS: 3
    Citation - Scopus: 3
    Copper and Nickel Complexes Based on 4-((4 Diazenyl)-3 Synthesis, Characterization, X-Ray Studies, Dft Calculations, Molecular Docking and Antimicrobial Activity
    (Elsevier, 2024) Amin, Mina A.; Diker, Halide; Sahin, Onur; Varlikli, Canan; Soliman, Ahmed A.
    Two new copper(II) and nickel(II) complexes were prepared using 4-((4-nitrophenyl)diazenyl)-3-(trifluoromethyl)-1H-pyrazol-5-ol (ndtp) and well-characterized spectroscopically and thermally and via X-ray studies. X-ray studies confirmed the formation of two octahedral complexes, containing two ndtp and two coordinated DMF molecules. The two complexes were evaluated in vitro against Escherichia coli, Pseudomonas aeruginosa, , Staphylococcus aureus and Bacillus cereus. . [Ni(ndtp)2(DMF)2] 2 (DMF) 2 ] showed an enhanced antibacterial activity against the different bacterial strains compared to the free ligand and that of the [Cu(ndtp)2(DMF)2]. 2 (DMF) 2 ]. The mean inhibition zones exhibited by [Ni(ndtp)2(DMF)2] 2 (DMF) 2 ] were 14.7+0.6, +0.6, 14.0+1.0, +1.0, and 16.3+0.6 +0.6 mm against Escherichia coli, , Staphylococcus aureus and Bacillus cereus, , respectively. Molecular docking studies of the two complexes were performed with DNA gyrase of Escherichia coli (PDB ID: 6F86) to evaluate the potential antibacterial activities, and it was proved that the complexes were efficient for the receptor.