Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/11147/7148

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Access Right: Open AccessStart date: 2010

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Now showing 1 - 10 of 4690
  • Erratum
    Erratum to “Plasma Proteomic Markers of Interleukin-1β Pathway Associated With Incident Age-Related Macular Degeneration in Persons with AIDS” [Ophthalmol Sci. 2025;5:100794] (Ophthalmology Science (2025) 5(5), (S2666914525000922), (10.1016/J.xops.2025.100794))
    (Elsevier Inc., 2026) Hunt, P.W.; Olshen, A.B.; Murad, N.; Ambayec, G.C.; Sezgin, E.; Schneider, M.F.; Jabs, D.A.
    The publisher of this journal would like to note an error in the article “Plasma Proteomic Markers of Interleukin-1β Pathway Associated with Incident Age-Related Macular Degeneration in Persons with AIDS.” An earlier version of Figure 1 was inadvertently published instead of the final revised figure. The correct figure appears below.[Figure presented] © 2025 American Academy of Ophthalmology
  • Article
    3D Magnetic Nanocomposite Aerogel (3D-MANCA) for Humidity Sensing and Dye Adsorption Applications
    (Institute of Physics, 2026) Shah, N.; Tetik, H.; Lin, D.
    Introducing magnetic properties to aerogels not only opens new application areas but also enhances their performance in various applications. Herein, we report a novel 3D magnetic agar nanocomposite aerogel (3D-MANCA) with outstanding characteristics such as high porosity, magnetic property, rapid swelling behavior, and a unique stimuli-driven electrical conductivity. Agar and nanocellulose mixture were selected as the matrix material, while magnetic Fe<inf>3</inf>O<inf>4</inf> nanoparticles, CuO nanoparticles, and graphene nanopowder were incorporated as functional additives. 3D-MANCA obtained after a uni-directional freeze casting process exhibited a highly-ordered microporosity. It showed excellent magnetic properties and methylene-blue adsorption capability and a great performance as humidity sensor. © 2026 The Author(s). Published on behalf of The Electrochemical Society by IOP Publishing Limited.
  • Article
    Reduced Phase Space Quantization and Quantum Corrected Entropy of Schwarzschild-De Sitter Horizons
    (Elsevier B.V., 2026) Jalalzadeh, S.; Moradpour, H.
    This paper investigates the quantization of the Schwarzschild–de Sitter (SdS) black hole (BH) using the Misner–Sharp–Hernandez (MSH) mass as the internal energy in a reduced phase space framework. After introducing the canonical variables of the reduced phase space, we derive a discrete spectrum for the surface areas of the BH event horizon (EH) as well as MSH masses. We utilized the MSH mass spectrum to obtain the entropy of the BH. The entropy of the BH and cosmic EHs reveals a logarithmic correction to the Bekenstein–Hawking term. Our results support the robustness of the logarithmic form of quantum corrections in SdS thermodynamics. © 2026 The Authors.
  • Article
    Improved Colorectal Gland Segmentation in Histopathology Images with Adaptive Resizer-Enhanced U-Net Models
    (Springer Science and Business Media Deutschland GmbH, 2026) Fidan, E.; Gumus, A.
    Utilizing low-resolution images for computer vision tasks such as classification and segmentation can sometimes hinder the model’s ability to accurately learn essential features. While using high-resolution images and designing compatible models might seem like viable solutions, they are not always feasible due to energy efficiency and graphical computation constraints. Downsizing images for model training and application is an effective approach for improving computational efficiency and optimizing model performance.The bilinear resizing method, commonly employed for this purpose, inherently causes information loss due to its numerical approach, which relies solely on the four nearest pixel values to compute each target pixel. This limitation becomes more pronounced with high-resolution images, where the down sampling process intensifies the loss of critical information. However, recent advancements have introduced adaptive resizer modules, which dynamically adjust image dimensions to better preserve essential features before processing by deep learning models. In this study, an adaptive resizer-based segmentation framework is proposed for the gland segmentation task, which is crucial for accurate disease diagnosis, particularly in cancer analysis. Three distinct encoder-decoder architecture segmentation models are assessed for image segmentation using the Colorectal Adenocarcinoma Gland (CRAG) gland segmentation database. Each architecture was tested separately, employing six different backbone encoders that were pretrained on the ImageNet dataset. The comparative analysis showed that the adaptive resizer improved segmentation performance, increasing the Intersection over Union (IoU) metric by an average of 5.6%. This enhancement raised the lowest IoU from 62% to 70% and the highest to 78%. The code is available on GitHub at https://github.com/miralab-ai/adaptive-resizer-segmentation. © The Author(s) 2026.
  • Conference Object
    Material Optimisation for Future Double Skin Façade System Design
    (Institute of Physics, 2025) Unluturk, M.S.; Kazanasmaz, Z.T.; Ekici, B.; Göksal Özbalta, T.G.
    Façades have a significant impact on energy consumption in interiors. Designers aimed to reduce energy consumption by developing different façade systems. Double Skin Façade (DSF) aims to increase thermal and ventilation performance in the interior. The depth of the cavity gap between the two façade layers with air inside may adversely affect indoor daylight performance. In addition, studies in the literature indicate that this façade system shows optimum performance in cold climates. With the right design decisions, the DSF system can provide optimum performance in hot climates. In building designs with DSF systems in these climate zones, daylight and energy simulations can make the right design decisions. However, the climate crisis (CC) is increasing air temperatures and sunshine hours in hot and arid climate zones. Simulations are based on current climate data, and the recommendations obtained may not show optimum performance in the future. The study aims to propose an educational building model with a DSF system that will provide optimum visual comfort for 50 years in the Mediterranean climate type (CSA). Meteonorm has created weather scenarios for Izmir for 2050 and 2080. Opossum and Galapagos carried out the optimisation process using this data. The study proposes models that will perform optimally in Izmir for 50 years. © Published under licence by IOP Publishing Ltd.
  • Conference Object
    Design of Adaptive Shading Device with Rigid Origami Technique: Improving Outdoor Thermal Comfort on Pathways of University Campus
    (Institute of Physics, 2025) Dağlier, Y.; Ekici, B.; Korkmaz, K.
    Since urbanization emerged with consequences for the built environment, shadows have played a key role in outdoor comfort. In hot climates, shadow has become a vital element in public spaces as it significantly affects social interaction on various occasions, such as university campus areas. The current state of the art shows that the role of shadings in outdoor environments is crucial to increasing pedestrian comfort and supporting overall well-being. While trees and canopies are commonly used for shading, their applicability is sometimes limited in pedestrian pathways. For example, the Izmir Institute of Technology (IZTECH) campus copes with outdoor discomfort during the extremely hot summer days. Due to the changing environmental conditions, static shading devices offer effective shadows only at specific times. This creates a necessity to design shading devices that can rotate and fold to mitigate temperatures more effectively and increase outdoor thermal comfort. A parametric shading model was developed using Grasshopper and Kangaroo Physics®, and its effectiveness was analyzed using Building Performance Simulation (BPS) tools. The research integrates heuristic optimization techniques to enhance shading performance, including Galapagos (Genetic Algorithm) and Opossum (RBF-opt and CMA-ES). Results indicate that the proposed kinetic shading devices reduced the universal thermal climate index (UTCI) by approximately 20% during peak sunlight hours. These findings suggest that adaptive shading strategies efficiently improve outdoor thermal comfort in urban public spaces. © 2025 Published under licence by IOP Publishing Ltd.
  • Conference Object
    Energy-Efficient Urban Design Proposal in Urban Heat Island Formation: The Case of CSA Climate
    (Institute of Physics, 2025) Unluturk, I.U.; Yavuz, E.; Unluturk, M.S.; Akgun, B.
    Nowadays, unplanned construction resulting from urban growth and population increase reduces the resilience of cities and their historical texture and increases the need for buildings for housing in cities. This situation, which increases the density/height of city buildings, increases the surface temperature and reduces the green tissue, causes urban heat island. In this study, the Dumlupinar neighbourhood of Balıkesir, which attracts attention with its historical texture and where new buildings are designed in certain parts today, will be discussed. First, the areas with traditional and new buildings in the region are modelled parametrically in the Rhino/Grasshopper interface, obtained and compared through Dragonfly software and an urban prototype is created. However, in the computational design algorithms to be performed, not only today's weather scenario but also the weather scenario of 2050 was used. Models were created to minimise the urban heat island in 2050 climate conditions. This urban prototype is a proposal for sustainable cities to be built in cities in CSA climate types (Mediterranean climate). This proposal will guide municipalities in designing energy-efficient and carbon-neutral cities using the urban model of the urban heat island effect. © 2025 Institute of Physics Publishing. All rights reserved.
  • Article
    Influence of Innovative Thawing Approaches on the Thermal and Chemical Structure Changes of Frozen Beef Liver
    (Springer, 2026) Avsar, Nazlican; Uzuner, Sibel
    Freezing effectively preserves meat quality, but the formation of ice crystals during the process can impact tenderness and functionality. Thawing is a critical step, as it can lead to physicochemical changes-such as protein oxidation and further ice crystal growth-that may reduce product quality and consumer appeal. Therefore, the thawing method plays a key role in determining the final quality of frozen meat. This study evaluated the physicochemical and structural characteristics of beef liver frozen at - 18 +/- 2 degrees C for 20 h and thawed using three methods: water immersion thawing (WIT), ultrasonic bath thawing (UBT), and air fryer thawing (AFT). No significant differences in drip loss were observed among the UBT, AFT, and WIT samples (p > 0.05). Color measurements (L*, a*, b*) were significantly higher in raw liver than in AFT and UBT samples (p < 0.05). Compared to raw liver and the WIT method, AF and UB thawing lowered the denaturation temperature, indicating reduced thermal stability. The lowest metmyoglobin (MetMb) content was found in the UBT sample (36.57 +/- 0.87%), followed by the AFT sample (41.71 +/- 1.29%), suggesting better pigment preservation with UB thawing. Highlights circle AF and UB thawing methods resulted in a lower denaturation temperature. circle UBT showed the lowest MetMb content, helping to minimize oxidation. circle UBT caused less damage to protein chains and better preserved structural stability. circle UBT preserved desirable aroma characteristics more effectively.
  • Article
    Anticancer Properties of Newly Synthesized Pyrrole Derivatives as Potential Tyrosine Kinase Inhibitors
    (Wiley, 2026) Kaya, Meltem; Kara, Yunus; Sanli-Mohamed, Gulsah
    The anticancer activity of a series of newly synthesized pyrrole derivatives was systematically evaluated in HeLa cervical cancer cells, focusing on their potential as tyrosine kinase inhibitors and modulators of the mTOR signaling pathway. This study builds on our previous synthetic work by investigating the biological effects of seven structurally characterized compounds (d1-d7). Among them, compounds d1 and d3 exhibited the most potent cytotoxicity, with IC50 values of 140.6 mu M and 366.4 mu M, respectively, after 48 h of treatment. Both compounds significantly impaired cell cycle progression-d1 induced S-phase arrest, while d3 caused G1-phase arrest-and markedly suppressed cell migration in wound healing assays. Mechanistically, these effects were accompanied by reduced phosphorylation of p70S6K (Thr389, Ser421/424) and increased p-4EBP1, indicating inhibition of mTORC1 signaling. These findings suggest that d1 and d3 are promising lead compounds with dual antiproliferative and anti-migratory activity in cervical cancer, mediated through modulation of the PI3K/Akt/mTOR axis.
  • Article
    Ten Questions Concerning Circularity in the Built Environment
    (Pergamon-Elsevier Science Ltd, 2026) Kayacetin, N. Cihan; Aslanoglu, Rengin; Piccardo, Chiara; Afacan, Yasemin; Masera, Gabriele; Li, Qiuxian; Van Hoof, Joost
    The rapid urbanisation of our societies calls for an urban renewal movement, including developing new areas to accommodate housing facilities and services and regenerating existing urban areas. Yet, urban renewal projects pose trade-offs impacting both environmental and socio-economic aspects. The renovation and new construction of buildings can escalate the use of energy and material resources as well as increasing greenhouse gas emissions. The European Union plays a leading role in promoting the transition towards sustainable and inclusive cities, whereas other regions such as North America, Australia and Asia follow suit via Circular Economy Action Plans or Frameworks, highlighting the need to enhance resource efficiency in buildings through the use of durable and circular materials. Current research on resource efficiency in buildings follows the Circular Economy concept, which aims to reduce the use of raw materials and the waste of existing materials while retaining their value for as long as possible. However, the role of the circular economy in sustainable transition and the adoption of its principles in urban contexts remain unclear while its practical implementation still faces significant challenges, including the lack of analytical instruments and assessment methods as well as co-creative approaches. This 'Ten Questions contribution' provides an overview of the pressing issues concerning circularity in the built environment, the state-of-the-art and best practices, challenges and benefits, policies and regulations, as well as numerous strategies applied on the building and neighbourhood level, assessment methodologies and future trends.