Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
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Article Synthesis, Characterization, Crystal Structure, Electrochemical and Photoluminescence Properties, Dft and Molecular Docking Studies, and Antimicrobial Activities of Two Mononuclear Nickel (II) Complexes With Pyrazole-Derived Ligands(Elsevier, 2025) Amin, Mina A.; Diker, Halide; Sahin, Onur; Varlikli, Canan; Soliman, Ahmed A.Two octahedral nickel complexes; [Ni(fdtp)2(DMF)2] (1) and [Ni(dcdtp)2(DMF)2] (2), based on 4-((3-fluorophenyl)diazenyl)-3-(trifluoromethyl)-1H-pyrazol-5-ol (fdtp) and 4-((2,4-dichlorophenyl)diazenyl)-3-(trifluoromethyl)-1H-pyrazol-5-ol (dcdtp) were synthesized. The complexes were characterized spectroscopically (FTIR, UV-Vis, Photoluminescence), Mass spectrometry, elemental analyses, electrochemically, thermally, and through Single-crystal X-ray investigations. The formation of the complexes was confirmed by the existence of Ni-O and Ni-N vibrations at bonds were observed as weak bands at 526-497 and 470-438 cm-1. According to the thermogravimetric analyses, the complexes were thermally stable and had relatively high activation energies (585.81 and 730.07 kJ mol-1 for 1, and 2, respectively). Cyclic voltammograms showed that the anodic potential region of 1 and 2 exhibited two irreversible oxidation peaks at 1.34 V &1.55 V and 1.41 V & 1.63 V, respectively, attributed to metal-localized oxidation. The complexes showed enhanced antibacterial activities compared to free ligands and comparable to the standard. The inhibition zones exhibited via 1 were about 21.7, 19.3, and 26.7 mm versus Escherichia coli (E. coli), Staphylococcus aureus (S. Aureus), and Bacillus Subtits (B. Subtits), respectively. Docking studies supported the antibacterial investigations; the binding energies of the complexes were -8.81 and -9.69 kcal/mol for 1 and 2 respectively, against E. coli (PDB ID: 6F86).Article Citation - Scopus: 3A Reaction-Based Scenario for Fluorescence Probing of Au(iii) Ions in Human Cells and Plants(Royal Soc Chemistry, 2023) Eren, Merve Cevik; Eren, Ahmet; Dartar, Suay; Kaya, Beraat Umur; Ucuncu, Muhammed; Varlikli, Canan; Emrullahoglu, MustafaA BODIPY-based fluorophore decorated with a gold specific reactive handle (e.g., 2-alkynylallyl alcohol) displayed a ratiometric fluorescence change in response to Au3+ ions with extraordinary selectivity over other competing metal species, including Hg2+, Cu2+, Zn2+ and Pd2+. By way of a gold-catalyzed intramolecular cyclisation-isomerisation reaction sequence, a BODIPY construct with an extended p-conjugation transformed into a new structure with a relatively short p-system. This unique chemical transformation was accompanied by, and resulted in, a dramatic shift in the emission and absorption wavelength, which could be monitored as distinct changes in the color of the solution's emission. Apart from its outstanding analytical performance in solution, including a quick response time (<10 s), unique specificity, a high-fold ratio-metric change (62-fold), and a remarkably low detection limit (358 nM), the probe also proved useful in monitoring Au3+ ions in human cells and plants (e.g., Nicotiana benthamiana).