Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/11147/7148

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2022 - 202421

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Department: search.filters.department.Izmir Institute of TechnologyPublisher: search.filters.publisher.Mdpi

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Now showing 1 - 10 of 21
  • Article
    Citation - WoS: 4
    Citation - Scopus: 3
    An Investigation of Rna Methylations With Biophysical Approaches in a Cervical Cancer Cell Model
    (Mdpi, 2024) Saglam, Buket; Akkus, Onur; Akcaoz-Alasar, Azime; Ceylan, Cagatay; Guler, Gunnur; Akgul, Bunyamin
    RNA methylation adds a second layer of genetic information that dictates the post-transcriptional fate of RNAs. Although various methods exist that enable the analysis of RNA methylation in a site-specific or transcriptome-wide manner, whether biophysical approaches can be employed to such analyses is unexplored. In this study, Fourier-transform infrared (FT-IR) and circular dichroism (CD) spectroscopy are employed to examine the methylation status of both synthetic and cellular RNAs. The results show that FT-IR spectroscopy is perfectly capable of quantitatively distinguishing synthetic m(6)A-methylated RNAs from un-methylated ones. Subsequently, FT-IR spectroscopy is successfully employed to assess the changes in the extent of total RNA methylation upon the knockdown of the m(6)A writer, METTL3, in HeLa cells. In addition, the same approach is shown to accurately detect reduction in total RNA methylation upon the treatment of HeLa cells with tumor necrosis factor alpha (TNF-alpha). It is also demonstrated that m(1)A and m(6)A methylation induce quite a distinct secondary structure on RNAs, as evident from CD spectra. These results strongly suggest that both FT-IR and CD spectroscopy methods can be exploited to uncover biophysical properties impinged on RNAs by methyl moieties, providing a fast, convenient and cheap alternative to the existing methods.
  • Review
    Citation - WoS: 13
    Citation - Scopus: 18
    Review of Cell Level Battery (calendar and Cycling) Aging Models: Electric Vehicles
    (Mdpi, 2024) Yarimca, Gulsah; Cetkin, Erdal
    Electrochemical battery cells have been a focus of attention due to their numerous advantages in distinct applications recently, such as electric vehicles. A limiting factor for adaptation by the industry is related to the aging of batteries over time. Characteristics of battery aging vary depending on many factors such as battery type, electrochemical reactions, and operation conditions. Aging could be considered in two sections according to its type: calendar and cycling. We examine the stress factors affecting these two types of aging in detail under subheadings and review the battery aging literature with a comprehensive approach. This article presents a review of empirical and semi-empirical modeling techniques and aging studies, focusing on the trends observed between different studies and highlighting the limitations and challenges of the various models.
  • Article
    Citation - WoS: 2
    Citation - Scopus: 1
    A Safe Fiber-Optic-Sensor-Assisted Industrial Microwave-Heating System
    (Mdpi, 2024) Yuksel, Kivilcim; Merdin, Oguz Deniz; Kinet, Damien; Merdin, Murat; Guyot, Corentin; Caucheteur, Christophe
    Industrial microwave-heating systems are pivotal in various sectors, including food processing and materials manufacturing, where precise temperature control and safety are critical. Conventional systems often struggle with uneven heat distribution and high fire risks due to the intrinsic properties of microwave heating. In this work, a fiber-optic-sensor-assisted monitoring system is presented to tackle the pressing challenges associated with uneven heating and fire hazards in industrial microwave systems. The core innovation lies in the development of a sophisticated fiber-optic 2D temperature distribution sensor and a dedicated fire detector, both designed to significantly mitigate risks and optimize the heating process. Experimental results set the stage for future innovations that could transform the landscape of industrial heating technologies toward better process quality.
  • Review
    Citation - WoS: 1
    Citation - Scopus: 2
    Bergamot (<i>citrus Bergamia</I>), a (poly)phenol-Rich Source for Improving Osteosarcopenic Obesity: a Systematic Review
    (Mdpi, 2024) Mazzola, Giuseppe; Rondanelli, Mariangela; Baron, Giovanna; Zupo, Roberta; Castellana, Fabio; Clodoveo, Maria Lisa; Perna, Simone
    This systematic review investigates the potential of bergamot, a polyphenol-rich citrus fruit, in improving osteosarcopenic obesity, a condition characterized by the simultaneous presence of osteoporosis, obesity, and sarcopenia. Bergamot extracts have been suggested to possess several pharmacological properties, including anti-inflammatory and antioxidant effects, which could be useful in the management of age-related diseases and neuromuscular health. The review highlights the promising effects of bergamot extracts on skeletal muscle mass and function, particularly in the context of obesity, metabolic syndrome, osteosarcopenic obesity, and osteoporosis. Furthermore, some studies have shown that bergamot extracts can improve the metabolic balance, endothelial function, and maximal oxygen uptake in athletes, highlighting their potential benefits for skeletal muscle health. Taken together, these results suggest that bergamot extracts, especially those rich in polyphenols, may be a valuable adjunct in the management of osteosarcopenic obesity and other associated clinical conditions involving pro-inflammatory effects on organs and tissues.
  • Article
    Citation - WoS: 3
    Citation - Scopus: 3
    A Viability Study of Thermal Pre-Treatment for Recycling of Pharmaceutical Blisters
    (Mdpi, 2024) Gokelma, Mertol; Diaz, Fabian; Capkin, Irem Yaren; Friedrich, Bernd
    Pharmaceutical packaging is one of the most used packaging types which contains aluminum and plastics. Due to increasing amounts of waste and rising environmental concerns, recycling approaches are being investigated. Since blisters usually contain a balanced amount of plastics and metals, most of the approaches focus on recycling only one material. Therefore, more sustainable recycling approaches which recover both plastic and aluminum fractions are needed. This study investigates the thermal behavior and degradation mechanisms of plastic-rich and aluminum-rich pharmaceutical blisters using various analytical techniques. Structural characterization revealed that plastic-rich blisters have a thicker profile with plastic and aluminum layers, while aluminum-rich blisters consist of plastic layers between aluminum sheets. Thermal degradation analysis showed two main stages for both types: plastic-rich blisters (polyvinyl chloride) exhibited significant weight loss and long-chain hydrocarbon formation between 210 and 285 degrees C, and aluminum-rich blisters (polyamide/nylon) degraded from 240 to 270 degrees C. Differential Scanning Calorimetry and Fourier Transform Infrared Spectroscopy analyses confirmed the endothermic behavior of such a transformation. The gas emissions analysis indicated an increased formation of gasses from the thermal treatment of plastic-rich blisters, with the presence of oxygen leading to the formation of carbon dioxide, water, and carbon monoxide. Thermal treatment with 5% O2 in the carrier gas benefited plastic-rich blister treatment, reducing organic waste by up to 80% and minimizing burning risk, leveraging pyrolytic carbon for protection. This method is unsuitable for aluminum-rich blisters, requiring reduced oxygen or temperature to prevent pyrolytic carbon combustion and aluminum oxidation.
  • Article
    Citation - WoS: 1
    Citation - Scopus: 1
    Effects of Size and Mechanical Pre-Treatment on Aluminium Recovery From Municipal Solid Waste Incineration Bottom Ash
    (Mdpi, 2024) Gokelma, Mertol; Hatipoglu, Utku; Vallejo-Olivares, Alicia; Tuzgel, Rabia onen; Kivrak, Olcay; Bazoglu, Elif; Tranell, Gabriella
    Municipal solid waste (MSW) is incinerated to reduce the volume and recover energy and materials. The generation of MSW has been increasing over the past few decades due to the increase in population and changing consumption habits. Rising environmental and economic concerns have increased the importance of waste treatment and recovery. Currently, MSW may take three alternate or parallel routes: direct recycling, incineration, or landfill, depending on the country and location. MSW incineration has three products in addition to energy: bottom ash, fly ash, and off-gas. After incineration, bottom ash usually still contains many materials to be recovered, such as glass, ceramics, and metals with a degree of oxidation. This study focuses on aluminium recovery from MSW incineration bottom ash from two different countries. The 2-30 mm fraction of aluminium particles was characterized in terms of its size, shape, and oxide thickness, and its effects on aluminium recovery were investigated. In addition, the ability of mechanical pre-treatment to remove oxides prior to melting was studied. The results were compared with the analytical modeling developed in this study. An increasing particle size and surface area resulted in an increase in aluminium recovery. Mechanical pre-treatment increased the yield for smaller particles to a larger extent than larger particles due to the difference in the oxide/metal ratio.
  • Review
    A Qualitative Survey on Community Detection Attack Algorithms
    (Mdpi, 2024) Tekin, Leyla; Bostanoglu, Belgin Ergenc
    Community detection enables the discovery of more connected segments of complex networks. This capability is essential for effective network analysis. But, it raises a growing concern about the disclosure of user privacy since sensitive information may be over-mined by community detection algorithms. To address this issue, the problem of community detection attacks has emerged to subtly perturb the network structure so that the performance of community detection algorithms deteriorates. Three scales of this problem have been identified in the literature to achieve different levels of concealment, such as target node, target community, or global attack. A broad range of community detection attack algorithms has been proposed, utilizing various approaches to tackle the distinct requirements associated with each attack scale. However, existing surveys of the field usually concentrate on studies focusing on target community attacks. To be self-contained, this survey starts with an overview of community detection algorithms used on the other side, along with the performance measures employed to evaluate the effectiveness of the community detection attacks. The core of the survey is a systematic analysis of the algorithms proposed across all three scales of community detection attacks to provide a comprehensive overview. The survey wraps up with a detailed discussion related to the research opportunities of the field. Overall, the main objective of the survey is to provide a starting and diving point for scientists.
  • Article
    Citation - WoS: 5
    Citation - Scopus: 4
    Gravitational Particle Production and the Hubble Tension
    (Mdpi, 2024) Erdem, Recai
    The effect of gravitational particle production of scalar particles on the total effective cosmic energy density (in the era after photon decoupling till the present) is considered. The effect is significant for heavy particles. It is found that gravitational particle production results in an effective increase in the directly measured value of the Hubble constant H0, while it does not affect the value of the Hubble constant in the calculation of the number density of baryons at the present time that is used to calculate recombination redshift. This may explain why the Hubble constants determined by local measurements and non-local measurements (such as CMB) are different. This suggests that gravitational particle production may have a non-negligible impact on H0 tension.
  • Review
    Citation - WoS: 21
    Citation - Scopus: 21
    Advancement in the Modeling and Design of Composite Pressure Vessels for Hydrogen Storage: a Comprehensive Review
    (Mdpi, 2024) Bouhala, Lyazid; Karatrantos, Argyrios; Reinhardt, Heiner; Schramm, Norbert; Akin, Beril; Rauscher, Alexander; Tanoglu, Metin
    The industrial and technological sectors are pushing the boundaries to develop a new class of high-pressure vessels for hydrogen storage that aim to improve durability and and endure harsh operating conditions. This review serves as a strategic foundation for the integration of hydrogen tanks into transport applications while also proposing innovative approaches to designing high-performance composite tanks. The goal is to offer optimized, safe, and cost-effective solutions for the next generation of high-pressure vessels, contributing significantly to energy security through technological advancements. Additionally, the review deepens our understanding of the relationship between microscopic failure mechanisms and the initial failure of reinforced composites. The investigation will focus on the behavior and damaging processes of composite overwrapped pressure vessels (COPVs). Moreover, the review summarizes relevant simulation models in conjunction with experimental work to predict the burst pressure and to continuously monitor the degree of structural weakening and fatigue lifetime of COPVs. Simultaneously, understanding the adverse effects of in-service applications is vital for maintaining structural health during the operational life cycle.
  • Article
    Citation - WoS: 5
    Citation - Scopus: 4
    Reconstructing Energy-Efficient Buildings After a Major Earthquake in Hatay, Türkiye
    (Mdpi, 2024) Saleh, Yousif Abed Saleh; Akkurt, Gulden Gokcen; Turhan, Cihan
    T & uuml;rkiye's earthquake zone, primarily located along the North Anatolian Fault, is one of the world's most seismically active regions, frequently experiencing devastating earthquakes, such as the one in Hatay in 2023. Therefore, reconstructing energy-efficient buildings after major earthquakes enhances disaster resilience and promotes energy efficiency through retrofitting, renovation, or demolition and reconstruction. To this end, this study proposes implementing energy-efficient design solutions in dwelling units to minimize energy consumption in new buildings in Hatay, Southern Turkiye, an area affected by the 2023 earthquake. This research focused on a five-story residential building in the district of Kurtlusar & imath;maz & imath;, incorporating small-scale Vertical-Axis Wind Turbines (VAWTs) with thin-film photovoltaic (PV) panels, along with the application of a green wall surrounding the building. ANSYS Fluent v.R2 Software was used for a numerical investigation of the small-scale IceWind turbine, and DesignBuilder Software v.6.1.0.006 was employed to simulate the baseline model and three energy-efficient design strategies. The results demonstrated that small-scale VAWTs, PV panels, and the application of a green wall reduced overall energy use by 8.5%, 18%, and 4.1%, respectively. When all strategies were combined, total energy consumption was reduced by up to 28.5%. The results of this study could guide designers in constructing innovative energy-efficient buildings following extensive demolition such as during the 2023 earthquake in Hatay, T & uuml;rkiye.