Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
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Article Elasto-Plastic Phase-Field Modeling of Fracture in FDM-Printed ABS Components: Numerical Implementation and Experimental Validation(Taylor and Francis Ltd., 2025) Dengiz, C.G.; Yorulmazlar, B.; Dorduncu, M.; Taşdemirci, A.This study presents a computational framework for predicting fracture behavior in 3D-printed acrylonitrile butadiene styrene (ABS) components using an elasto-plastic phase-field approach (PFA) implemented within the ABAQUS finite element environment. A user-defined element (UEL) subroutine is employed to solve the coupled displacement and damage equations through a staggered scheme. The model captures crack initiation and propagation under various stress states and specimen configurations, including pure shear, oblique shear, and tensile loading, without requiring predefined crack paths or remeshing. Numerical predictions are validated against experimental results, showing strong agreement in both force–displacement response and failure morphology. Parametric studies are conducted to assess the influence of mesh size, time increment, length scale parameter, and critical energy release rate on fracture response. The results demonstrate that while the peak reaction force is largely insensitive to these parameters, displacement at fracture and damage localization are significantly affected. The calibrated model successfully captures elasto-plastic fracture evolution in printed ABS specimens, confirming its robustness and generalizability. The proposed framework offers a reliable tool for failure analysis of polymer-based additively manufactured components and establishes a foundation for future extensions involving anisotropy, fatigue, and microstructural heterogeneity. © 2025 Taylor & Francis Group, LLC.Article Design Strategies to Optimize Polymeric Vectors for mRNA Delivery(Taylor and Francis Ltd., 2025) Turhan, Z.Y.; Savaş, M.; Alakbarov, A.; Bulmus, V.mRNA holds great promise for preventing and treating a variety of diseases, from infectious diseases to diverse cancers, owing to its transient expression, lack of genomic integration, and scalable production. Among non-viral vectors, polymeric carriers are attractive due to their synthetic versatility and stability, which allow for precise tuning for efficient mRNA delivery. Their scalability further supports the applicability of polymeric vectors. Studies have addressed the room for improvement in polymeric systems for mRNA delivery and have adapted varying approaches depending on the type of polymeric structure, including but not limited to PEGylation, hydrophobic modification, and incorporation of responsive or targeting moieties. This review summarizes advances in polymeric vectors for mRNA delivery and highlights how distinct structural modifications influence toxicity, mRNA transfection efficiency, biodistribution, intracellular trafficking and immune activation, providing a framework for the rational design of next-generation polymeric vectors that can fully realize the clinical potential of mRNA therapeutics. © 2025 Taylor & Francis Group, LLC.Article From Work to Leisure: ”Transforming Kitchen Spaces, Technologies, and Practices in Türkiye, 1930s-2020s.”(Taylor and Francis Ltd., 2025) Emgin, B.; Bektaş Ata, L.; Karaosmanoğlu, D.Kitchens are more than functional spaces; they reflect and shape cultural values, technologies, and ideals of modern life. Framing the kitchen as an orchestrating concept that brings together images, materials, and competencies, this article examines how idealized settings and tools have produced shifting narratives of modernity and redefined meanings, functions, and everyday practices in Türkiye from the 1930s to the present. It highlights the transformation of the kitchen from a moralizing space to one of entertainment and creativity across three eras: the ordered workshop of the 1930s, the cozy living room of the 1970s, and the technological hub of the 2000s. Drawing on archival research from a larger project on the social history of domestic technologies in Türkiye, the article analyzes newspapers, magazines, TV commercials, social media, and films to reveal how domestic ideals have been negotiated through kitchen spaces. © 2025 Informa UK Limited, trading as Taylor & Francis Group.Article Industrial History and Heritage of the Karaburun Mercury Mining District, Türkiye(Taylor and Francis Ltd., 2025) Yılmazer, Aslıhan; Gönülal, Yasemin Özcan; Yüceer, HülyaMining metallic resources has been important to technological advancement since prehistoric times and has contributed to the progress of civilisation. Mining heritage includes sites and structures related to mining that reveal historical and cultural insights. The remains of structures in the mercury mining district on the Karaburun peninsula of Izmir in Türkiye, which includes the Kalecik, Karareis and Dikencik mines, is one such site. Despite its abandonment and subsequent damage, research has highlighted the importance of the district during the late Ottoman empire and the early years of the Republic as a source of cinnabar, the most common source ore for refining elementary mercury. Comparable mines elsewhere have been transformed into heritage sites and tourist attractions, such as at Monte Amiata in Italy and Idrija in Slovenia. In view of the potential, this study aimed to establish the historical and industrial significance of the Karaburun mercury mining district through detailed research and site survey to form a robust base for a holistic conservation approach. © 2025 Elsevier B.V., All rights reserved.Article Citation - WoS: 1Citation - Scopus: 1Optimized Lithium(I) Recovery From Geothermal Brine of Germencik, Türkiye, Utilizing an Aminomethyl Phosphonic Acid Chelating Resin(Taylor and Francis Ltd., 2025) Recepoğlu, Y.K.This study investigates the performance of Lewatit TP 260 ion exchange resin for the efficient recovery of lithium (Li(I)) from geothermal water sourced from the Germencik Geothermal Power Plant in Türkiye. A series of batch sorption experiments were performed to evaluate the influence of key parameters, including resin dosage, solution pH, temperature, initial Li(I) concentration, and contact time, on the Li(I) recovery process. The optimal conditions were determined to be a resin dose of 0.5 g per 25 mL of geothermal water, pH in the range of 6–8, and a temperature of 25°C. Under these conditions, the resin achieved a maximum Li(I) recovery rate of 71% from the geothermal water. Sorption isotherms were further analyzed using the Langmuir, Freundlich, and Dubinin-Radushkevich (D-R) models. Among these, the Langmuir model provided the best fit (R² = 0.9841), suggesting a maximum sorption capacity (qm) of 4.31 mg/g. Continuous recovery experiments conducted in column mode confirmed the practical applicability of Lewatit TP 260, achieving a total sorption capacity of 0.41 mg Li(I)/mL resin. The findings exhibit the potential of this resin as a viable sorbent for sustainable Li(I) extraction from geothermal brines, supporting the development of green energy technologies and contributing to the circular economy. © 2024 Taylor & Francis Group, LLC.Article On-Site Measurements of Temperature and Humidity Conditions for the Comparison of Urban and Rural Sub-Spaces of Traditional Settlements: Historical City of Muğla, Turkey(Taylor and Francis Ltd., 2024) Timur,B.A.; Başaran,T.; İpekoğlu,B.One of the significant processes that ensures realistic determination of the energy needs of historical buildings is case-specific definition of their local microclimatic conditions. Accordingly, the aim of this study is to determine differences for the parameters of temperature and humidity in urban and rural sub-settlements of the historical city, Muğla/Turkey. Study method consists of on-site measurements of these variables in sub-settlements for comparisons. As a result, it was identified urban zone shows heat island characteristics with warmer, drier, and more stable conditions; while rural sub-settlement remains cooler, more humid, and more erratic. In parallel, calculated extents of these differences demonstrate the significance and necessity of on-site measurements and consequential microclimatic zoning of historical cities as conservation/planning tools for responding to the thermal needs of architectural heritage. A key application of these processes would be the establishment of local databases of case-specific weather data to be used in thermal simulation assessments. © 2023 Taylor & Francis.Article Citation - Scopus: 11Chemical Composition and Biological Activities of Cypriot Propolis(Taylor and Francis Ltd., 2022) Nalbantsoy, A.; Sarıkahya, N.B.; Özverel, C.S.; Barlas, A.B.; Kırcı, D.; Akgün, İ.H.; Yalçın, Tansel; Düven, GamzePropolis compositions are highly variable, depending on the geographic region and the season of collection. In this study, propolis samples from seven different regions of Cyprus were studied for the first time by means of chemical content and biological activities. Secondary metabolite composition was determined by LC-HRMS. While the major flavonoids found were isosakuranetin, naringenin, rhamnocitrin, diosmetin, chrysin and acacetin, interestingly verbascoside, a phenylethanoid glycoside, and chlorogenic acid were identified as the major compounds in the ethanol-water extracts. α-Pinene was detected as the major compound of propolis extracts according to the volatile compositions via GC-MS. Karaoglanoglu and Tirmen extracts, presenting different chemical profiles, exerted enormous cytotoxic activity by MTT assay (IC50: 2.36–11.56 µg/mL; 1.44–9.33 µg/mL, respectively). The highest iNOS inhibition potential was detected in the Karpaz extract (IC50:2.6 µg/mL) in LPS induced RAW 264.7 cells whereas the Guzelyurt sample demonstrated remarkable antioxidant (88.82 ± 0.10%) and antimicrobial activities (with a MIC value of 31.2 μg/mL against S. aureus, S. epidermidis, E. faecium, and E. faecalis). © 2021 International Bee Research Association.Article Effects of Span 60 Template and Freeze Drying on Zinc Borate Produced From Zinc Nitrate Hexahydrate and Borax Decahydrate(Taylor and Francis Ltd., 2022) Alp, Burcu; Gönen, Mehmet; Atakul Savrık, Sevdiye; Balköse, DevrimZinc borate is an important additive to polymers and lubricants. The process variables such as reactant concentration, presence of template in precipitating medium and drying method determine the composition and particle size of zinc borates. In the present study, zinc borate precipitate obtained by mixing aqueous zinc nitrate and borax decahydrate solutions was dried either by conventional method or by freeze drying. The products were well characterized by advanced methods. Zinc borate from 1 mol dm(-3) reactants had (2.1 +/- 0.5)x(2.5 +/- 0.5)x(1.3 +/- 0.2) mu m and (0.5 +/- 0.1)x(1.3 +/- 0.1)x(0.028 +/- 0.01) mu m dimensions by conventional and freeze drying respectively. Individual particles smaller in size is obtained since the particles are not agglomerated due to absence of surface tension of liquid water for case of freeze drying. Planar particles agglomerated into 20 to 60 mu m crystals in the presence of template Span 60 in 1 mol dm(-3) reactants for conventional drying. Nano zinc borate particles with primary particle size of (46 +/- 9) nm were obtained by decreasing the reactant concentration to 0.1 mol dm(-3). The primary particle size was decreased to (40 +/- 3) nm by addition of Span 60 to dilute solutions. However zinc borate nanoparticles obtained from dilute solutions adhered to each other forming agglomerates during conventional drying. Their freeze drying would allow formation of a freely flowing nano powder.Article Citation - WoS: 2Citation - Scopus: 2A New Fluorescent 'turn On' Probe for Rapid Detection of Biothiols(Taylor and Francis Ltd., 2020) Üçüncü, Muhammed; Zeybek, Hüseyin; Karakuş, Erman; Üçüncü, Canan; Emrullahoğlu, MustafaWe designed and synthesised a novel molecular probe exhibiting high selectivity and sensitivity towards reactive sulphur species (RSS) over other amino acids and biologically relevant species, as well as scrutinised its spectroscopic behaviours under physiological conditions and in living milieu. We used an electrophilic cyanate group as a masking agent to block the excited state intramolecular proton transfer process of 2-(2-cyanato-3-methoxyphenyl)benzo[d]thiazole (HMBT-OCN), which readily hydrolyses to the highly fluorescent structure, 2-(2'-Hydroxy-3'-methoxyphenyl) benzothiazole (HMBT-OH), in the presence of reactive sulphur species. [GRAPHICS] .Article Citation - WoS: 7Citation - Scopus: 11Chemical Composition and Biological Activities of Cypriot Propolis(Taylor and Francis Ltd., 2021) Nalbantsoy, Ayşe; Sarıkahya, Nazlı Böke; Özverel, Cenk Serhan; Barlas, Ayşe Berçin; Kırcı, Damla; Akgün, İsmail Hakkı; Yalçın, Tansel; Güven, Gamze; Kışla, Duygu; Demirci, Betül; Topçu, Gülaçtı; Gören, Ahmet CeyhanPropolis compositions are highly variable, depending on the geographic region and the season of collection. In this study, propolis samples from seven different regions of Cyprus were studied for the first time by means of chemical content and biological activities. Secondary metabolite composition was determined by LC-HRMS. While the major flavonoids found were isosakuranetin, naringenin, rhamnocitrin, diosmetin, chrysin and acacetin, interestingly verbascoside, a phenylethanoid glycoside, and chlorogenic acid were identified as the major compounds in the ethanol-water extracts. alpha-Pinene was detected as the major compound of propolis extracts according to the volatile compositions via GC-MS. Karaoglanoglu and Tirmen extracts, presenting different chemical profiles, exerted enormous cytotoxic activity by MTT assay (IC50: 2.36-11.56 mu g/mL; 1.44-9.33 mu g/mL, respectively). The highest iNOS inhibition potential was detected in the Karpaz extract (IC50:2.6 mu g/mL) in LPS induced RAW 264.7 cells whereas the Guzelyurt sample demonstrated remarkable antioxidant (88.82 +/- 0.10%) and antimicrobial activities (with a MIC value of 31.2 mu g/mL against S. aureus, S. epidermidis, E. faecium, and E. faecalis).