Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/11147/7148

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  • Article
    FTIR Spectroscopy Coupled With Chemometrics for Evaluating Functional Food Efficacy in an in Vitro Model of Iron Deficiency Anemia
    (Elsevier Science Ltd, 2026) Dalyan, Eda; Cavdaroglu, Cagri; Ozen, Banu; Gulec, Sukru
    Vibrational spectroscopy offers a rapid, cost-effective approach for studying biological systems. This study employs Fourier Transform Infrared (FTIR) spectroscopy, combined with Soft Independent Modeling of Class Analogy (SIMCA), to evaluate treatment outcomes for iron deficiency anemia (IDA). The model was built using spectra from healthy and anemic cells, then validated with cells treated with commonly used iron supplements. In calibration, 9 of 10 control and all IDA samples were correctly classified; 14 of 15 validation samples were identified as healthy. The model was applied to cells treated with protein-iron complexes. All samples treated with a 60:1 protein-iron ratio matched the healthy group, while 3 of 4 treated with a 10:1 ratio matched the IDA group. These results were further supported by iron-regulated gene expression of transferrin receptor (TFR) and (Ankyrin Repeat Domain 37) ANKRD37. FTIR coupled with chemometrics enables rapid assessment of functional effects and shows potential for screening functional ingredients in anemia-targeted food products.
  • Article
    Citation - Scopus: 105
    Moisture Sorption Isotherm Characteristics of Peppers
    (Elsevier Science Ltd, 2001) Kaymak-Ertekin,F.; Sultanoglu,M.
    Moisture sorption isotherms of green and red peppers were determined at three different temperatures (30 °C, 45 °C and 60 °C) and relative humidities (10-90%), using the standard static, gravimetric method. The GAB, Halsey, Oswin and BET sorption models were tested to fit the experimental data. A nonlinear regression analysis method was used to evaluate the constants of four sorption equations. The Halsey equation gave the best fit to the experimental sorption data for a wide range of water activity while BET gave the best fit for a water activity range of 0.1-0.5. The agreement between experimental and calculated values was found to be satisfactory. The isosteric heats of desorption and adsorption of water were determined from the equilibrium data at different temperatures using the Clasius-Clapeyron equation.