Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
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Conference Object Citation - WoS: 5Citation - Scopus: 3Hierarchical Successive Stream Selection for Heterogeneous Network Interference(Institute of Electrical and Electronics Engineers Inc., 2014) Aycan, Esra; Özbek, Berna; Le Ruyet, DidierThis paper presents a hierarchical stream selection approach to deal with the interference in a heterogeneous network where different cell types are coexisting with each other to increase the sum capacity. Due to the variety of the transmit powers between the macro and small cells, interference levels are different. The proposed solution hierarchically selects the strongest streams of each cell with a contribution to the sum rate, while constructing the streams via singular value decomposition (SVD). In order to reduce the interference, the channel matrices of the remaining streams are projected orthogonally to the virtual transmit channel and virtual receive channel of the selected stream. The performance evaluations are obtained by considering different locations of small cells with respect to the macro cell. It is shown that the proposed method can dynamically select more streams in heterogeneous networks and achieve higher data rates compared to the existing algorithms. © 2014 IEEE.Article Citation - WoS: 56Citation - Scopus: 63Thioredoxin Is Required for Deoxyribonucleotide Pool Maintenance During S Phase(American Society for Biochemistry and Molecular Biology, 2006) Koç, Ahmet; Mathews, Christopher K.; Wheeler, Linda J.; Gross, Michael K.; Merrill, Gary FredericThioredoxin was initially identified by its ability to serve as an electron donor for ribonucleotide reductase in vitro. Whether it serves a similar function in vivo is unclear. In Saccharomyces cerevisiae, it was previously shown that Δtrx1 Δtrx2 mutants lacking the two genes for cytosolic thioredoxin have a slower growth rate because of a longer S phase, but the basis for S phase elongation was not identified. The hypothesis that S phase protraction was due to inefficient dNTP synthesis was investigated by measuring dNTP levels in asynchronous and synchronized wild-type and Δtrx1 Δtrx2 yeast. In contrast to wild-type cells, Δtrx1 Δtrx2 cells were unable to accumulate or maintain high levels of dNTPs when α-factor- or cdc15-arrested cells were allowed to reenter the cell cycle. At 80 min after release, when the fraction of cells in S phase was maximal, the dNTP pools in Δtrx1 Δtrx2 cells were 60% that of wild-type cells. The data suggest that, in the absence of thioredoxin, cells cannot support the high rate of dNTP synthesis required for efficient DNA synthesis during S phase. The results constitute in vivo evidence for thioredoxin being a physiologically relevant electron donor for ribonucleotide reductase during DNA precursor synthesis.