Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/11147/7148

Browse

Filters

2014 - 20162

Settings

Scopus Q: search.filters.scopusQuartile.Q2Subject: search.filters.subject.Metal nanoparticles

Search Results

Now showing 1 - 2 of 2
  • Article
    Citation - WoS: 65
    Citation - Scopus: 72
    Effect of Peg Grafting Density and Hydrodynamic Volume on Gold Nanoparticle-Cell Interactions: an Investigation on Cell Cycle, Apoptosis, and Dna Damage
    (American Chemical Society, 2016) Uz, Metin; Bulmuş, Volga; Alsoy Altınkaya, Sacide
    In this study, interactions of polyethylene glycol (PEG)-coated gold nanoparticles (AuNPs) with cells were investigated with particular focus on the relationship between the PEG layer properties (conformation, grafting density, and hydrodynamic volume) and cell cycle arrest, apoptosis, and DNA damage. Steric hindrance and PEG hydrodynamic volume controlled the protein adsorption, whereas the AuNP core size and PEG hydrodynamic volume were primary factors for cell uptake and viability. At all PEG grafting densities, the particles caused significant cell cycle arrest and DNA damage against CaCo2 and PC3 cells without apoptosis. However, at a particular PEG grafting density (∼0.65 chains/nm2), none of these severe damages were observed on 3T3 cells indicating discriminating behavior of the healthy (3T3) and cancer (PC3 and CaCo2) cells. It was concluded that the PEG grafting density and hydrodynamic volume, tuned with the PEG concentration and AuNP size, played an important role in particle-cell interactions.
  • Article
    Citation - WoS: 17
    Citation - Scopus: 26
    Thixoforming of A356/Sic and A356/Tib2 Nanocomposites Fabricated by a Combination of Green Compact Nanoparticle Incorporation and Ultrasonic Treatment of the Melted Compact
    (Springer Verlag, 2014) Kandemir, Sinan; Atkinson, Helen V.; Weston, David P.; Hainsworth, Sarah V.
    Thixoforming is a type of semi-solid processing which is based on forming metals in the semi-solid state rather than fully liquid or solid state. There have been no reports of the thixoforming of nanocomposites in the literature. The incorporation of ceramic nanoparticles into liquid metals is a challenging task for the fabrication of metal matrix nanocomposites due to their large surface-to-volume ratio and poor wettability. Previous research work by a number of workers has highlighted the challenges with the incorporation of nanoparticles into liquid aluminum alloy. In the present study, SiC and TiB2 nanoparticles with an average diameter between 20 and 30 nm were firstly incorporated into green compacts by a powder forming route, and then the compacts were melted and treated ultrasonically. The microstructural studies reveal that the engulfment and relatively effective distribution of the nanoparticles into the melt were achieved. The hardness was considerably improved with only 0.8 wt pct addition of the nanoparticles. The nanocomposites were successfully thixoformed at a solid fraction between 0.65 and 0.70. The microstructures, hardness, and tensile mechanical properties of the thixoformed nanocomposites were investigated and compared with those of the as-received A356 and thixoformed A356 alloys. The tensile properties of the thixoformed nanocomposites were significantly enhanced compared to thixoformed A356 alloy without reinforcement, indicating the strengthening effects of the nanoparticles.