Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/11147/7148

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  • Article
    A Comprehensive Database and a New Model for the Axial Response of Heat-Damaged Concrete Before and After FRP Confinement
    (Springer, 2025) Akdag, Nefise; Demir, Ugur
    In this study, a total of 330 concrete specimens, compiled from existing experimental data, are systematically reviewed to assess their post-fire axial stress-strain behavior before and after circumferential confinement with fiber-reinforced polymers (FRPs). The selection criteria for the database are as follows: (i) studies had to be published in English, (ii) both lateral and axial ultimate strains must have been measured, (iii) the use of additional strengthening materials in combination with FRPs was excluded, (iv) only plain concrete specimens were considered, and (v) specimen dimensions and instrumentation details had to be explicitly reported. The dataset is structured to include heating/cooling and curing conditions, specimen properties, and FRP characteristics. Subsequently, the predictive accuracy of available models for post-fire axial strength and ultimate strain of concrete members, both before and after FRP confinement, is evaluated. The results based on the reviewed comprehensive database indicate that these models are inadequate in capturing the observed behavior in the experiments. As such, a new analytical model is developed based on the compiled dataset. The proposed model demonstrated reliable predictive performance in terms of post-fire axial response of concrete before and after FRP confinement while remaining user-friendly for practical engineering applications. This is done such that universal design guidelines on the behavior of heat-damaged concrete strengthened by FRP composites can be reliably formulated.
  • Review
    Citation - Scopus: 2
    Wnt/β-catenin Signaling in Central Nervous System Regeneration
    (2025) Nazli, D.; Bora, U.; Ozhan, G.
    The Wnt/β-catenin signaling pathway plays a pivotal role in the development, maintenance, and repair of the central nervous system (CNS). This chapter explores the diverse functions of Wnt/β-catenin signaling, from its critical involvement in embryonic CNS development to its reparative and plasticity-inducing roles in response to CNS injury. We discuss how Wnt/β-catenin signaling influences various CNS cell types-astrocytes, microglia, neurons, and oligodendrocytes-each contributing to repair and plasticity after injury. The chapter also addresses the pathway's involvement in CNS disorders such as Alzheimer's and Parkinson's diseases, psychiatric disorders, and traumatic brain injury (TBI), highlighting potential Wnt-based therapeutic approaches. Lastly, zebrafish are presented as a promising model organism for studying CNS regeneration and neurodegenerative diseases, offering insights into future research and therapeutic development. © 2024. The Author(s), under exclusive license to Springer Nature Switzerland AG.