Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
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Article Citation - WoS: 6Citation - Scopus: 6Benzodiazepine Derivatives From Marine-Derived Streptomyces Cacaoi 14cm034(ACG Publications, 2021) Çetinel Aksoy, Semiha; Küçüksolak, Melis; Uzel, Ataç; Bedir, Erdal7-methoxy-8-hydroxy cycloanthranilylproline (2), a new natural product with pyrrolobenzodiazepine (PBD) framework, was isolated from marine-derived actinobacterium Streptomyces cacaoi 14CM034, together with cycloanthranilylproline (1). Structural elucidation of the compounds was based on FTIR, 1D-(H-1 and C-13 NMR), 2D-NMR (COSY, HMBC and NOESY) and HR-MS analyses. Compounds 1 and 2 exhibited notable antimicrobial activity. The presence of PBD derivatives in S. cacaoi was first demonstrated with this study.Article Citation - WoS: 14Citation - Scopus: 16Antimicrobial Activity and Chemical Composition Screening of Epilobium Montanum Root(Association of Pharmaceutical Teachers of India, 2017) Canlı, Kerem; Yetgin, Ali; Akata, Ilgaz; Altuner, Ergin MuratMedical herbs have many bioactive component and they are used in microbial treatment since ancient time. The resistance of pathogen to antibiotic is became a critical problem, so novel antimicrobial agent related research is required. Epilobium montanum related antimicrobial research doesn’t exist, therefore root of this medicinal plant investigation was applied against 17 bacteria and 1 fungi by using disk diffusion method. These microbial species include Bacillus, Enterobacter, Enterococcus, Escherichia, Klebsiella, Listeria, Pseudomonas, Salmonella, Staphylococcus and Candida genera. Besides, chemical composition of this sample was determined by Gas Chromatography-Mass Spectroscopy. The results were presented that E. montanum has antimicrobial activity against all tested microbial species except E. coli. Seventeen major chemical components were determined, but some composition of this sample is not match with library. For this reason, this medicinal plant contain unknown molecules and this molecules should be analysed by NMR spectra for 3D structure determination and identification.Article Citation - WoS: 15Citation - Scopus: 19Antimicrobial Activity and Chemical Composition Screening of Anacyclus Pyrethrum Root(Association of Pharmaceutical Teachers of India, 2017) Canlı, Kerem; Yetgin, Ali; Akata, Ilgaz; Altuner, Ergin MuratMedical herbs have many bioactive component and they are used in microbial treatment since ancient times. The resistance of pathogens to antibiotics became a critical problem, so researches for novel antimicrobial agents are required. Anacyclus pyrethrum (pellitory, Spanish chamomile or Mount Atlas daisy) is commonly used as a traditional medicine, therefore the antimicrobial activity of the root of this medicinal plant was investigated against 17 bacteria and 1 fungi by using disk diffusion method. The test strains include Bacillus, Enterobacter, Enterococcus, Escherichia, Klebsiella, Listeria, Pseudomonas, Salmonella, Staphylococcus and Candida genera. Besides, chemical composition of this sample was determined by Gas Chromatography-Mass Spectroscopy analysis. The results were presented that A. pyrethrum has antimicrobial activity against all tested microbial species except E. faecalis and S. typhimurium. Eighteen major chemical components were determined, but some composition of this sample is not match with library. For this reason, this medicinal plant contain unknown molecules and this molecules should be analysed NMR spectra for 3D structure determination and identification.Article Citation - WoS: 48Citation - Scopus: 58Micro-Encapsulation of Ozonated Red Pepper Seed Oil With Antimicrobial Activity and Application To Nonwoven Fabric(John Wiley and Sons Inc., 2013) Özyıldız, Figen; Karagönlü, S.; Başal, Güldemet; Uzel, Ataç; Bayraktar, OğuzIn recent years, functional fabrics possessing antimicrobial activity have drawn significant interest because antibiotic resistance is becoming widespread among pathogenic micro-organisms. The aim of this study was to produce microcapsules incorporating ozonated red pepper seed oil (ORPSO) with antimicrobial properties and apply them to nonwoven fabrics to prepare functional textiles. Red pepper seed oil (RPSO) was ozonated and micro-encapsulated via a complex coacervation method using gelatin (GE) and gum arabic (GA) as wall materials. While micro-encapsulation yield and oil loading decreased with increases in the amount of surfactant, the mean particle size increased. The antimicrobial activity of the oil was tested via the disc diffusion method. The microcapsules were also tested using the agar well method. While RPSO had no effect on the test micro-organisms, the ORPSO and microcapsules containing ORPSO were found to be active against the test micro-organisms. The microcapsules were then applied to nonwoven fabric using the padding method to produce a disposable functional textile. The microcapsule-impregnated functional fabrics provided a 5 log decrease in 1 h. It is therefore possible to functionalize nonwoven fabrics to have antimicrobial activity against antibiotic-resistant micro-organisms, using microcapsules containing ORPSO.Article Citation - WoS: 29Citation - Scopus: 32Antimicrobial Activity of Tio2-Coated Orthodontic Ceramic Brackets Against Streptococcus Mutans and Candida Albicans(Springer Verlag, 2010) Özyıldız, Figen; Güden, Mustafa; Uzel, Ataç; Karaboz, İsmail; Akil, Övünç; Bulut, H.Polycrystalline alumina ceramic orthodontic brackets were coated with anatase TiO2 film via a sol-gel dip-coating method. The surface structure morphology and composition of the films were evaluated via scanning electron microscopy, atomic force microscopy, and X-ray diffraction. The antimicrobial activity of the ceramic brackets was assessed against two oral pathogens, S. mutans and C. albicans. The results demonstrated that TiO 2-coated brackets exposed to low energy UV-A illumination efficiently reduced the populations of test microorganisms relative to the uncoated brackets. The reduction efficiencies were 98% for S. mutans ATCC 10449 and 93% for C. albicans ATCC 60193. © The Korean Society for Biotechnology and Bioengineering and Springer 2010.