Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/11147/7148

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  • Article
    Citation - WoS: 7
    Citation - Scopus: 7
    A Comprehensive Study on Burst Pressure Performance of Aluminum Liner for Hydrogen Storage Vessels
    (ASME, 2021) Kangal, Serkan; Sayı, Abdülmecit Harun; Ayakdaş, Ozan; Kartav, Osman; Aydın, Levent; Artem, Hatice Seçil; Aktaş, Engin; Yücetürk, Kutay; Tanoğlu, Metin; Kandemir, Sinan; Beylergil, Bertan
    This paper presents a comparative study on the burst pressure performance of aluminum (Al) liner for type-III composite overwrapped pressure vessels (COPVs). In the analysis, the vessels were loaded with increasing internal pressure up to the burst pressure level. In the analytical part of the study, the burst pressure of the cylindrical part was predicted based on the modified von Mises, Tresca, and average shear stress criterion (ASSC). In the numerical analysis, a finite element (FE) model was established in order to predict the behavior of the vessel as a function of increasing internal pressure and determine the final burst. The Al pressure vessels made of Al-6061-T6 alloy with a capacity of 5 L were designed. The manufacturing of the metallic vessels was purchased from a metal forming company. The experimental study was conducted by pressurizing the Al vessels until the burst failure occurred. The radial and axial strain behaviors were monitored at various locations on the vessels during loading. The results obtained through analytical, numerical, and experimental work were compared. The average experimental burst pressure of the vessels was found to be 279 bar. The experimental strain data were compared with the results of the FE analysis. The results indicated that the FE analysis and ASSC-based elastoplastic analytical approaches yielded the best predictions which are within 2.2% of the experimental burst failure values. It was also found that the elastic analysis underestimated the burst failure results; however, it was effective for determining the critical regions over the vessel structure. The strain behavior of the vessels obtained through experimental investigations was well correlated with those predicted through FE analysis.
  • Book Part
    Citation - Scopus: 20
    Experimental MicroRNA Detection Methods
    (Humana Press, 2022) Yaylak, Bilge; Akgül, Bünyamin
    MicroRNAs (miRNAs) are considerably small yet highly important riboregulators involved in nearly all cellular processes. Due to their critical roles in posttranscriptional regulation of gene expression, they have the potential to be used as biomarkers in addition to their use as drug targets. Although computational approaches speed up the initial genomewide identification of putative miRNAs, experimental approaches are essential for further validation and functional analyses of differentially expressed miRNAs. Therefore, sensitive, specific, and cost-effective microRNA detection methods are imperative for both individual and multiplex analysis of miRNA expression in different tissues and during different developmental stages. There are a number of well-established miRNA detection methods that can be exploited depending on the comprehensiveness of the study (individual miRNA versus multiplex analysis), the availability of the sample and the location and intracellular concentration of miRNAs. This review aims to highlight not only traditional but also novel strategies that are widely used in experimental identification and quantification of microRNAs. © 2022, Springer Science+Business Media, LLC, part of Springer Nature.