Master Degree / Yüksek Lisans Tezleri

Permanent URI for this collectionhttps://hdl.handle.net/11147/3008

Browse

Filters

2011 - 201912020 - 20231

Settings

Access type: Open accessSubject: search.filters.subject.Materials science

Search Results

Now showing 1 - 2 of 2
  • Master Thesis
    Characterization and Recyclability of Pharmaceutical Blisters
    (01. Izmir Institute of Technology, 2023) Gökelma, Mertol; Akkurt, Sedat; Akkurt, Sedat; Gökelma, Mertol; Akkurt, Sedat; 03.09. Department of Materials Science and Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
    Packaging is one of the largest industries in the world. Pharmaceutical blister packages are the most preferred packaging type in the pharmaceutical industry. Especially after the COVID-19 pandemic, the use of pharmaceutical packaging has become widespread with the increasing demand for drugs. Pharmaceutical blister packages typically contain thin sheets of plastic and aluminium and generate substantial solid waste. Since these packages have a multi-layered and complex structure, they are difficult to recycle. Before recycling, plastic and aluminium need a separation process. Chemical separation or thermal processes can be used for separation. The aim of this study is to characterize different pharmaceutical blister types with SEM-EDS (Scanning electron microscopy- Energy dispersive X-ray spectroscopy), TGA (Thermogravimetric Analysis), DSC (Differential scanning calorimetry), ICP-MS (Inductively coupled plasma mass spectrometry), and FTIR (Fourier Transform Infrared Spectroscopy) and to review the different reagents used in the pharmaceutical blister layer separation process. In addition to thermal degradation, the parameters and results of the separation processes were evaluated using hydrochloric acid, formic acid, acetic acid, sulfuric acid, ethanol, acetone, and organic solvents. It also evaluates the recyclability of the separated layers (plastic and aluminium). Its recyclability was evaluated by melting the aluminium fraction under salt consisting of a mixture of NaCl-KCl-CaF2. The plastic fraction was obtained in solid and liquid form by thermal degradation and analysed by GC-TCD (Gas Chromatography-Thermal conductivity detector).
  • Master Thesis
    Use of Metal Templates for Microcavity Formation in Alumina
    (Izmir Institute of Technology, 2011) Balkan, Sırma; Akkurt, Sedat; Akkurt, Sedat; 03.09. Department of Materials Science and Engineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
    Alumina ceramics with microtunnels are produced by compressing submicron sized alumina powder and Ti, Cu or stainless steel wires in a metal die before firing the compacts at 1350oC for 4 hours. Diameters of wires ranged from 50 to 125 micrometers. Copper was found to completely melt and flow away from the compact leaving no trace of copper in alumina. Stainless steel diffused out into the alumina leaving few pores behind. Titanium, on the other hand, diffused into alumina at 20 to 30micrometers/hour and left plenty of Kirkendal porosity behind. The amount of porosity could have been increased further by applying intensive milling to the powder. But no milling was done in this study and hence a complete micro-tunnel was not obtained. The Kirkendal effect was observed to be effective in producing pores in the ceramic. Densification behavior of the ceramic was also investigated with a vertical dilatometer. Densities up to 93% were achieved in the ceramics. In some tests Ti metal plates were used as diffusion couples with alumina compacts. Similar diffusion behavior was observed with plates and wires.