WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7150
Browse
4 results
Search Results
Article Citation - WoS: 3Citation - Scopus: 3Automated Labeling of Cancer Textures in Larynx Histopathology Slides Using Quasi-Supervised Learning(Science Printers and Publishers Inc., 2014) Önder, Devrim; Karaçalı, Bilge; Sarıoğlu, Sülen; Karaçalı, Bilge; 03.05. Department of Electrical and Electronics Engineering; 03. Faculty of Engineering; 01. Izmir Institute of TechnologyOBJECTIVE: To evaluate the performance of a quasisupervised statistical learning algorithm, operating on datasets having normal and neoplastic tissues, to identify larynx squamous cell carcinomas. Furthermore, cancer texture separability measures against normal tissues are to be developed and compared either for colorectal or larynx tissues. STUDY DESIGN: Light microscopic digital images from histopathological sections were obtained from laryngectomy materials including squamous cell carcinoma and nonneoplastic regions. The texture features were calculated by using co-occurrence matrices and local histograms. The texture features were input to the quasisupervised learning algorithm. RESULTS: Larynx regions containing squamous cell carcinomas were accurately identified, having false and true positive rates up to 21% and 87%, respectively. CONCLUSION: Larynx squamous cell carcinoma versus normal tissue texture separability measures were higher than colorectal adenocarcinoma versus normal textures for the colorectal database. Furthermore, the resultant labeling performances for all larynx datasets are higher than or equal to that of colorectal datasets. The results in larynx datasets, in comparison with the former colorectal study, suggested that quasi-supervised texture classification is to be a helpful method in histopathological image classification and analysis.Article Identification and Visualization of Cell Subgroups in Uncompensated Flow Cytometry Data(Elsevier Ltd., 2020) Güzel, Başak Esin Köktürk; Karaçalı, Bilge; Karaçalı, Bilge; 03.05. Department of Electrical and Electronics Engineering; 03. Faculty of Engineering; 01. Izmir Institute of TechnologyWe propose a new method for identification and visualization of cell-sub groups in uncompensated multi-color flow cytometry data. The method combines annealing-based model-free expectation-maximization to identify cell sub-groups and joint diagonalization on clustered data for better visualization. The proposed method was evaluated on a real, publicly available 8-color flow cytometry dataset manually gated beforehand for lymphocytes. The results obtained in three separable scenarios indicate that the method accurately identifies cell subgroups while properly adjusting visualization of identified cell groups by reducing the spectral overlap between the different fluorochrome channels.Conference Object Improved Quasi-Supervised Learning by Expectation-Maximization(Institute of Electrical and Electronics Engineers Inc., 2013) Karaçalı, Bilge; Karaçalı, Bilge; 03.05. Department of Electrical and Electronics Engineering; 03. Faculty of Engineering; 01. Izmir Institute of TechnologyIn this paper, a new statistical learning method was developed that implements the quasi-supervised learning method in an expectation-maximization loop. First, automatic strategies were generated that separated the samples drawn from different distributions into respective sample sets using the posterior probabilities computed via quasi-supervised learning based on partially separated samples. An expectation-maximization loop was then constructed by combining this procedure with the posterior probability computation step using the new separated sample sets. In controlled experiments on recognition problems with varying difficulties, the proposed method was observed to consistently outperform the plain quasi-supervised learning method.Conference Object Quasi-Supervised Learning on Dna Regions in Colon Cancer Histology Slides(Institute of Electrical and Electronics Engineers Inc., 2013) Köktürk, Başak Esin; Karaçalı, Bilge; Karaçalı, Bilge; 03.05. Department of Electrical and Electronics Engineering; 03. Faculty of Engineering; 01. Izmir Institute of TechnologyThe aim of this study, nuclei base automatic detection of cancerous regions via determination of DNA-rich regions in high definition histology images. In the study; DNA-rich regions were determined using k-means clustering and some mathematical morphology operations, the diseased regions were diagnosed using morphological characteristics via quasi-supervised learning. It's observed that quasi-supervised learning method successfully separates cancerous chromatin regions from others successfully with experiments of colon cross-section histology images.