WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7150
Browse
6 results
Search Results
Conference Object Nilotinib Significantly Induces Apoptosis in Imatinib Resistant K562 Cells, as Effectively as in Parental Sensitive Counterparts(Ferrata Storti Foundation, 2009) Baran, Yusuf; Can, Geylani; Ekiz, Hüseyin Atakan[No abstract available]Conference Object Imatinib Induces Autophagy Through Increasing the Expression Levels of Beclin-1 and Atg-5 Genes in Both Parental Sensitive and Imatinib-Resistant K562 Cells(Ferrata Storti Foundation, 2009) Baran, Yusuf; Can, Geylani; Ekiz, Hüseyin Atakan; Genç, S. G.[No abstract available]Conference Object Expression Analysis of 84 Genes Involved in Different Signalling Pathways of Cancer in Chronic Myeloid Leukemia Cells in Response To Nilotinib(Ferrata Storti Foundation, 2010) Baran, Yusuf; Camgöz, Aylin; Can, Geylani[No abstract available]Conference Object Gene Expression Profiles in Resveratrol Applied Acute Promyelocytic Leukemia Cells(Ferrata Storti Foundation, 2010) Baran, Yusuf; Çakır, Zeynep; Can, Geylani; Saydam, Güray; Şahin, Fahri[No abstract available]Conference Object Apoptotic Effects of Resveratrol on Imatinib Sensitive and Resistant K562 Chronic Myeloid Leukemia Cells(Ferrata Storti Foundation, 2010) Baran, Yusuf; Can, Geylani[No abstract available]Article Citation - WoS: 23Citation - Scopus: 25Role of Autophagy in the Progression and Suppression of Leukemias(Elsevier Ltd., 2012) Ekiz, Hüseyin Atakan; Can, Geylani; Baran, YusufAutophagy is a physiological process in which cellular components are degraded by the lysosomal machinery. Thereby, organelles are recycled and monomers are produced in order to maintain energy production. Current studies indicate autophagy might suppress or augment survival of cancer cells. Therefore, by elucidating the role of autophagy in cancer pathogenesis, novel therapeutic intervention points may be revealed. Leukemia therapy has advanced in recent years; but a definitive cure is still lacking. Since autophagy often is deregulated in this particular type of cancer, it is clear that future findings will have clinical implications. This review will discuss the current knowledge of autophagy in blood cancers. © 2011 Elsevier Ireland Ltd.