WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/11147/7150

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Author: search.filters.author.Polat, M.

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  • Article
    Citation - WoS: 1
    Citation - Scopus: 1
    Synthesis of Pristine Chitosan Foams with Enhanced Pore Structure, Surface Area, and Mechanical Strength for Tissue Engineering Applications
    (Iop Publishing Ltd, 2025) Polat, Mehmet; Polat, Hürriyet; Ozdamar, A. B.; Polat, H.; 01. Izmir Institute of Technology; 04. Faculty of Science; 04.01. Department of Chemistry; 03. Faculty of Engineering; 03.02. Department of Chemical Engineering
    With its excellent biocompatibility, biodegradability, and antimicrobial activity, chitosan is a promising scaffold material for hard-tissue engineering. Yet, pristine chitosan foams typically lack the strength and porosity required for such use. Here we present a simple emulsion-templating approach to fabricate pristine chitosan foams with optimized strength and porosity. Sodium dodecyl sulfate (SDS), a widely used biocompatible anionic surfactant, was employed at trace levels to aid polymerization. The foams display a dual-scale pore morphology. Cavities of 150-300 mu m are separated by around 50 mu m thick chitosan walls containing large interconnecting openings. The walls are further populated with meso- and macropores of 50-500 nm. This architecture should support cell attachment and growth, facilitate proliferation, and enhance nutrient transport and metabolic exchange. The structure yields high surface area (up to 10 m2 g-1). Mechanically, the thick-walled cavities impart both elastic recovery and high compressive resistance (255 kPa at 40% strain from foams polymerized with 4% chitosan). A preliminary drug-release study using vancomycin confirmed excellent loading and sustained release.
  • Article
    Citation - WoS: 24
    Citation - Scopus: 29
    Effect of Ph and Hydration on the Normal and Lateral Interaction Forces Between Alumina Surfaces
    (Elsevier Ltd., 2006) Polat, M.; Polat, Mustafa; Polat, Mehmet; Watari, K.; 04.05. Department of Pyhsics; 03.02. Department of Chemical Engineering; 03. Faculty of Engineering; 04. Faculty of Science; 01. Izmir Institute of Technology
    Interaction forces between alumina surfaces were measured using an AFM-colloid probe method at different pHs. For an α-alumina-sapphire system at acidic pH, the force curve exhibited a well-defined repulsive barrier and an attractive minimum. At basic pH, the interactive force was repulsive at all separations with no primary minimum. Lateral force measurements under the same conditions showed that frictional forces were nearly an order of magnitude smaller at basic pH than those observed at acidic pH. This behavior was attributed to the hydration of the alumina surface. Normal and lateral force measurements with the strongly hydrated ρ-alumina surfaces supported these findings. © 2006 Elsevier Inc. All rights reserved.