WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7150
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Article MIP-on-the-flow: Molecularly Imprinted Polymers in Microfluidic Sensing Systems(Elsevier Sci Ltd, 2026) Tekin, Hüseyin Cumhur; Sanko, Vildan; Yildirim, Ender; Tekin, H. Cumhur; Kulah, Haluk; 01. Izmir Institute of Technology; 03. Faculty of Engineering; 03.01. Department of BioengineeringThe integration of molecularly imprinted polymers (MIPs) with microfluidic systems has emerged as a powerful strategy for developing selective and sensitive analytical platforms. As "artificial receptors," MIPs offer robustness, reusability, and cost-effectiveness, while microfluidics enable precise fluid handling and miniaturized analysis. Together, they yield hybrid sensors capable of real-time detection. Recent advances in polymerization, nanoimprinting, and surface functionalization have tailored MIPs for seamless microfluidic integration. In parallel, innovations in soft lithography and 3D printing have expanded design possibilities for lab-on-chip architectures. Cutting-edge detection modalities, including electrochemical, optical, and mass-based transduction, have unlocked applications in biomedical diagnostics, environmental monitoring, and food safety. Examples include continuous biomarker monitoring, trace pollutant detection, and rapid food contaminant identification. Despite progress, challenges in reproducibility, large-scale fabrication, and commercialization remain. Addressing these through material innovations and scalable engineering will accelerate translation into point-ofcare testing, environmental protection, and global food security.Article Citation - WoS: 1Citation - Scopus: 1Electrochemical Sensors for Rapid Cardiovascular Disease Diagnostics(Amer Chemical Soc, 2025) Tekin, Hüseyin Cumhur; Tekin, H. Cumhur; 01. Izmir Institute of Technology; 03. Faculty of Engineering; 03.01. Department of BioengineeringCardiovascular diseases (CVDs) remain a leading cause of death, particularly in developing countries, where their incidence continues to rise. Traditional CVD diagnostic methods are often time-consuming and inconvenient, necessitating more efficient alternatives. Rapid and accurate measurement of cardiac biomarkers released into body fluids is critical for early detection, timely intervention, and improved patient outcomes. Electrochemical methods offer a robust solution by enabling rapid, sensitive, selective, and multiplex detection of CVD biomarkers, paving the way for early diagnosis and treatment advancements. This review highlights the performance and potential of electrochemical sensors for detecting specific CVD biomarkers and related organic molecules. It explores electrochemical sensing mechanisms, their evolution, the integration of nanotechnology, and diverse sensing platforms. It also examines emerging technologies such as microfluidic, smartphone-integrated sensors, and microneedle- and tattoo-based sensors. Challenges and opportunities in integrating electrochemical sensors into point-of-care (POC) and wearable devices are discussed. Finally, the review compares commercial CVD sensors with existing methods and outlines future directions to advance the field.