WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/11147/7150

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Now showing 1 - 10 of 459
  • Conference Object
    Suppression of STAT5A Increases Chemotherapeutic Sensitivity in Imatinib-Resistant and Imatinib-Sensitive K562 Cells
    (Ferrata Storti Foundation, 2010) Baran, Y.; Baran, Yusuf; Kosova, B.; Ekiz, Hüseyin Atakan; Tezcanli, B.; Ekiz, H.; Cakir, Z.; Selvi, S.
  • Conference Object
    Imatinib-Induced Apoptosis; a Possible Link To Topoisomerase Enzyme Inhibition
    (Ferrata Storti Foundation, 2010) Baran, Y.; Zencir, Z.; Cakir, Z.; Ozturk, E.; Topcu, Z.
  • Conference Object
    Changes in Protein Profiles of Multiple Myeloma Cells in Response To Bortezomib
    (Ferrata Storti Foundation, 2012) Baran, Y.; Turan, T.; Sanli-Mohamed, G.
  • Article
    Citation - WoS: 3
    Citation - Scopus: 3
    Nonlocal Static Modeling of Laminated Composite Shells Using Peridynamic Differential Operator in a Higher-Order Shear Deformation Framework
    (Elsevier Ltd, 2025) Bab, Yonca; Dorduncu, Mehmet; Kutlu, Akif; Markert, Bernd
    This study investigates the flexural behaviour of the laminated composite shells in the framework of Higher-Order Shear Deformation Theory (HSDT) and Peridynamic Differential Operator (PDDO), namely PD-HSDT, for the first time. Laminated composite shell structures are widely used in aerospace, automotive, and marine industries due to their high strength-to-weight ratio and design flexibility. Therefore, understanding their mechanical behavior under various loading conditions is crucial for ensuring structural reliability and performance optimization. However, such structures may possess complex curvatures and highly heterogenous laminate stackings, leading to inaccurate numerical stress analyses. The HSDT successfully captures displacement and stress distributions as well as cross-sectional warping through higher-order functions exist in the kinematics. Moreover, the PDDO represents the local derivatives in their nonlocal form, making it well-suited for problems involving higher-order derivatives and discontinuities. The governing equations and boundary conditions of the HSDT are solved by using the PDDO to accurately achieve the stress and displacement fields in the laminated composite shells. The robustness of the PD-HSDT is established by considering various loading and boundary conditions. The proposed approach demonstrates high accuracy in stress and displacement predictions when validated against reference solutions available in existing literature. This indicates strong potential for extending the methodology to more complex loading scenarios and damage mechanisms in future studies.
  • Article
    Citation - WoS: 3
    Citation - Scopus: 3
    A Novel Hybrid Thin Jacketing Method for Seismic Retrofitting of Substandard Reinforced Concrete Columns
    (Elsevier Ltd, 2025) Narlitepe, Furkan; Kian, Nima; Demir, Ugur; Demir, Cem; Ilki, Alper
    This paper introduces a novel hybrid thin jacketing method for seismic strengthening of substandard reinforced concrete (RC) columns for which structural repair mortar along with carbon fiber reinforced polymer (CFRP) and longitudinal steel bars are utilized. The method involves three application phases comprising a) removing the cover concrete, b) re-forming the cover concrete with structural repair mortar just after installing extra longitudinal steel bars c) transverse wrapping of CFRP sheets. The effect of using different types of structural repair mortar and its application process are other test parameters taken into account in this study. To evaluate the efficacy of the proposed method, a comprehensive experimental program was conducted, consisting of six largescale RC column specimens with square and rectangular cross-sections. For all of the specimens tested under a simultaneous constant axial load and reversed cyclic lateral loading, three main properties representing existing substandard RC columns such as a) insufficient transverse reinforcement, b) high axial load ratio (0.75) and, c) relatively high shear force corresponding to moment capacity to shear capacity ratios between 0.60 and 0.80, were considered. The responses of specimens were specified in terms of the lateral load-displacement curves, stiffness variation, ductility ratios, damage progression, and energy dissipation. The experimental results demonstrated that in case the retrofitting method is properly applied, the strengthened columns exhibit satisfactory performance in terms of strength and ductility with a remarkable improvement with respect to the substandard columns. Furthermore, a numerical study was conducted to validate the experimental results by using the OpenSees framework.
  • Conference Object
    Modeling of Glycolysis
    (Elsevier Science Bv, 2016) Batur, Aysem; Hamamci, Haluk; Buyukkileci (Sahin), Ceylan; Buyukkileci, Ali Oguz
  • Article
    Citation - WoS: 4
    Citation - Scopus: 2
    Elastic and Anelastic Behavior Associated With Structural Transitions in CsPbBr3
    (Amer Chemical Soc, 2025) Luo, Pingjing; He, Zhengwang; Yang, Dexin; Aktas, Oktay; Ding, Xiangdong; Zhang, Xuefeng
    Strain coupling and relaxation dynamics critically influence the photovoltaic and photoluminescent performances of metal halide perovskites. Here, resonant ultrasound spectroscopy is employed to study the elastic and anelastic properties associated with the octahedral tilting transitions in the optoelectronic semiconductor CsPbBr3 over the temperature range 303-468 K. The cubic-to-tetragonal transition near 405 K is marked by pronounced elastic softening accompanied by a sharp increase in acoustic loss. High anelastic loss below this transition reveals the presence of mobile ferroelastic twin walls that become pinned by lead vacancies at a temperature interval near 380 K in the tetragonal phase. The elastic softening in the cubic phase is strongly correlated to dynamic effects such as the local polar fluctuations. This local disordered effect is further verified by the anomalously high attenuation in the orthorhombic structure, in which the ferroelastic twin walls might become mobile.
  • Article
    Citation - WoS: 4
    Citation - Scopus: 2
    CFD-DEM Investigation of the Effects of Particle Size and Fluidization Regime on Heat Transfer in Fluidized Beds
    (Springer int Publ Ag, 2025) Alipoor, Mahdi; Kazemi, Saman; Zarghami, Reza; Mostoufi, Navid
    This paper presents an in-depth study of heat transfer in fluidized beds, employing the CFD-DEM technique. The primary focus is to examine the impacts of inlet gas velocity, fluidization regime, and particle size on the thermal behavior of fluidized beds. The results revealed that thermal convection predominantly governs heat transfer in fluidized beds, accounting for the largest fraction of the overall heat transfer process. Particle-fluid-particle thermal conduction was found to contribute approximately 10-20% of the heat transfer, whereas particle-particle conduction exhibits a minor role. Upon increasing the inlet gas velocity, the convection rate intensifies, whereas the particle-fluid-particle conduction rate decreases. Furthermore, the study highlights the differences in temperature distribution between turbulent and bubbling fluidized beds. Turbulent bed demonstrated a more uniform and homogenous particle temperature compared to bubbling. At similar fluidization numbers in bubbling beds, increasing particle diameter enhances thermal convection while reducing particle-fluid-particle conduction. In contrast, the turbulent regime shows minimal differences in heat transfer mechanisms when particle size varies. Additionally, smaller particles are found to significantly improve temperature uniformity in fluidized beds. A comprehensive comparison of simulation results with experimental data validates the accuracy of the employed model, reinforcing its ability to predict heat transfer in fluidized beds reliably. This research provides valuable insights into the complex interplay of various mechanisms of heat transfer within fluidized beds, enabling engineers and researchers to optimize bed performance and enhance temperature control in various industrial applications.
  • Article
    Citation - WoS: 2
    Citation - Scopus: 2
    Charting the Landscape of Design Cognition: Bridging the Gap Between Design Cognition and Cognitive Science
    (Taylor & Francis Ltd, 2025) Ata, F. Zeynep; Dogan, Fehmi
    This study examines the trajectory of cognitive studies on design processes (DesCog), charting its scientific landscape and interactions with cognitive science (CogSci). First, the study delineates the boundaries of DesCog within all published scholarly works. The analysis indicates that DesCog is a focused field with lesser impact on other fields, showing divergent bibliographic positions and connections for 'design cognition' and 'design thinking'. Second, the longitudinal evolution of DesCog is identified as gradually becoming more diverse and more connected. Third, DesCog's foundational connections to CogSci demonstrate that the relationship is spontaneous rather than following 'generalising interdisciplinarity' aims. The analysis indicates a unidirectional flow from CogSci to DesCog, with occasional reciprocal interactions. The volume and diversity of CogSci literature cited by DesCog appear narrow, and most cited publications are based on the information-processing theory of cognition. Fourth, the study identifies common themes at the intersection of two fields, demonstrating that creativity has been a focal theme for both since earlier studies. Finally, the individual impact of CogSci researchers on DesCog highlights the significance of Simon and Newell's influence. The study contributes to reflections on DesCog's knowledge production, underlining unidirectional knowledge flows from CogSci to DesCog and partial theoretical connections within the field.
  • Article
    Subinjectivity Relative To Cotorsion Pairs
    (MDPI, 2025) Alagoz, Yusuf; Alizade, Rafail; Buyukasik, Engin; Rozas, Juan Ramon Garcia; Oyonarte, Luis
    In this paper, we define and study the X-subinjectivity domain of a module M where X=(A,B) is a complete cotorsion pair, which consists of those modules N such that, for every extension K of N with K/N in A, any homomorphism f:N -> M can be extended to a homomorphism g:K -> M. This approach allows us to characterize some classical rings in terms of these domains and generalize some known results. In particular, we classify the rings with X-indigent modules-that is, the modules whose X-subinjectivity domains are as small as possible-for the cotorsion pair X=(FC,FI), where FI is the class of FP-injective modules. Additionally, we determine the rings for which all (simple) right modules are either X-indigent or FP-injective. We further investigate X-indigent Abelian groups in the category of torsion Abelian groups for the well-known example of the flat cotorsion pair X=(FL,EC), where FL is the class of flat modules.