WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7150
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Article Citation - WoS: 1Interfacial Properties of Aluminum/Glass-fiber Reinforced Polypropylene Sandwich Composites(Springer Verlag, 2013) Baştürk, S. B.; Guruşçu, A.; Tanoğlu, MetinAluminum/glass-fiber-reinforced polypropylene (Al/GFPP) laminates were manufactured by using various surface pretreatment techniques. Adhesion at the composite/metal interface was achieved by a surface pretreatment of Al sheets with amino-based silane coupling agents, incorporation of a polyolefin-based adhesive film and modification with a PP-based film containing 20 wt.% of maleic-anhydride-modified polypropylene (PP-g-MA). In order to increase the effect of bonding between components of the laminates, the combination of silane treatment and the addition of the PP-based film was also investigated. The mechanical properties (shear, peel, and bending strengths) of adhesively bonded Al/GFPP laminates were examined to evaluate the effects of the surface treatments mentioned. It was revealed that the adhesion in the laminated Al/GFPP systems could be improved by the treatment of aluminum surface with an amino-based silane coupling agent. Judging from the results of peel and bending strength, with incorporation of polyolefin-based films, adhesion in the Al/GFPP laminates increased significantly. The modification of Al/GFPP interfaces with a PP-g-MA/PP layer led to the highest improvement in their adhesion properties. The combination of surface modification with silane and addition of PP-based films did not yield the high bending strength desired. This may be due to the insufficient bonding between silane groups and PP-based films.Article Citation - WoS: 21Citation - Scopus: 24Development and Mechanical Behavior of Fml/Aluminium Foam Sandwiches(Springer Verlag, 2013) Baştürk, Suat Bahar; Tanoğlu, MetinIn this study, the Fiber-Metal Laminates (FMLs) containing glass fiber reinforced polypropylene (GFPP) and aluminum (Al) sheet were consolidated with Al foam cores for preparing the sandwich panels. The aim of this article is the comparison of the flexural properties of FML/Al foam sandwich panels bonded with various surface modification approaches (silane treatment and combination of silane treatment with polypropylene (PP) based film addition). The FML/foam sandwich systems were fabricated by laminating the components in a mould at 200 A degrees C under 1.5 MPa pressure. The energy absorbtion capacities and flexural mechanical properties of the prepared sandwich systems were evaluated by mechanical tests. Experiments were performed on samples of varying foam thicknesses (8, 20 and 30 mm). The bonding among the sandwich components were achieved by various surface modification techniques. The Al sheet/Al foam sandwiches were also consolidated by bonding the components with an epoxy adhesive to reveal the effect of GFPP on the flexural performance of the sandwich structures.Article Citation - WoS: 1Citation - Scopus: 2Emergence of Taperedducts in Vascular Designs With Laminar and Turbulent Flows(Begell House, 2014) Çetkin, ErdalHere we show that tapered ducts emerge in volumetrically bathed porous materials to decrease the resistance to the flow in laminar and turbulent flow regimes. The fluid enters the volume from one point and it is distributed to the entire volume. After bathing the volume, it is collected and leaves the volume from another point, i.e., two trees matched canopy to canopy. This paper shows that the flow architecture (i.e., design of the void spaces in a porous material) should be changed to obtain the minimum resistance to the flow as its size increases. Tapering the ducts decreases the order of the transition size, i.e., the size for changing from one construct to another to obtain the minimum pressure drop. The decrease in the pressure drop is 16% and 38% with the tapered ducts when the flow is laminar and turbulent, respectively. In addition, the volume ratios and the shape of the tapered ducts are documented. There is no design existing in nature with diameters of constant size in order to distribute and/or collect heat, fluid, and/or stress such as bones, rivers, veins, and tree branches. The emergence of the tapered ducts in designed porous materials is natural.Article Citation - WoS: 21Citation - Scopus: 22Daily Application of Low Magnitude Mechanical Stimulus Inhibits the Growth of Mda-Mb Breast Cancer Cells in Vitro(BioMed Central Ltd., 2014) Ölçüm, Melis; Özçivici, EnginIntroduction: Mechanical loads can regulate cell proliferation and differentiation at various stages of development and homeostasis. However, the extension of this regulatory effect of mechanical loads on cancer cells is largely unknown. Increased physical compliance is one of the key features of cancer cells, which may hamper the transmission of mechanical loads to these cells within tumor microenvironment. Here we tested whether brief daily application of an external low magnitude mechanical stimulus (LMMS), would impede the growth of MDA-MB-231 aggressive type breast cancer cells in vitro for 3 wks of growth. Methods: The signal was applied in oscillatory form at 90 Hz and 0.15 g, a regimen that would induce mechanical loads on MDA-MB-231 cells via inertial properties of cells rather than matrix deformations. Experimental cells were exposed to LMMS 15 min/day, 5 days/week in ambient conditions while control cells were sham loaded. Cell proliferation, viability, cycle, apoptosis, morphology and migration were tested via Trypan Blue dye exclusion, MTT, PI, Annexin V, Calcein-AM and phalloidin stains and scratch wound assays. Results: Compared to sham controls, daily application of LMMS reduced the number and viability of cancerous MDA-MB-231 cells significantly after first week in the culture, while non-cancerous MCF10A cells were found to be unaffected. Flow cytomety analyses suggested that the observed decrease for the cancer cells in the LMMS group was due to a cell cycle arrest rather than apoptosis. LMMS further reduced cancer cell circularity and increased cytoskeletal actin in MDA-MB-231 cells. Conclusion: Combined, results suggest that direct application of mechanical loads negatively regulate the proliferation of aggressive type cancer cells. If confirmed, this non-invasive approach may be integrated to the efforts for the prevention and/or treatment of cancer.Article Citation - WoS: 12Citation - Scopus: 11Inverted Fins for Cooling of a Non-Uniformly Heated Domain(Yıldız Teknik Üniversitesi, 2015) Çetkin, ErdalThis paper shows that the peak temperature of a non-uniformly heated region can be decreased by embedding high-conductivity tree-shaped inserts which is in contact with a heat sink from its stem. The volume fraction of the high-conductivity material is fixed, and so is the volume of the solid region. The length scale of the solid domain is L. Inside there is a cube-shaped region with length scale of 0.1L and heat production 100 times greater than the rest of the domain. The location of this hot spot was varied to uncover how its location affects the peak temperature and the design of inverted fins, i.e. highconductivity tree-shaped inserts. The volume fraction of the high-conductivity tree was varied for number of bifurcation levels of 0, 1 and 2. This showed that increasing the number of the bifurcation levels decreases the peak temperature when the volume fraction decreases. The optimal diameter ratios and optimal bifurcation angles at the each junction level are also documented. Y-shaped trees promise smaller peak temperatures than T-shaped trees. The location of the vascular tree in the z direction also affects the peak temperature when the heat generation is non-uniform. In addition, the peak temperature is minimum when z = 0.65L even though the hot spot is located on z = 0.75L.Article Citation - WoS: 6Citation - Scopus: 7Effect of an Inserted Porous Layer on Heat and Fluid Flow in a Vertical Channel With Mixed Convection(Vinca Inst Nuclear Sci, 2015) Çelik, Hasan; Mobedi, MoghtadaTemperature and velocity fields in a vertical channel partially filled with porous medium under mixed convection heat transfer condition are obtained. The heat transfer equation and equation of motion for clear and porous layer regions are written and solved analytically. The non-dimensionalization of the governing equations yields two Grashof numbers as Gr(c) and Gr(d) for clear and porous sections where Gr(d) = Da.Gr(c). The dimensionless governing parameters for the problem are Gr(c) (or Gr(d)), Da, thermal conductivity ratio, and thickness of porous layer. The temperature and velocity profiles for different values of Gr(c), Da, thermal conductivity ratio, and thickness of porous layer are plotted and their changes with the governing parameters are discussed. Moreover, the variation of pressure drop with the governing parameters is investigated. The decrease of porous layer thickness or thermal conductivity ratio increases the possibility of the downward flows. Thermal conductivity ratio plays important role on pressure drop, particularly for the channels with high values of Gr(c)/Re.Article Citation - WoS: 3Citation - Scopus: 4Constructal Structures for Self-Cooling: Microvascular Wavy and Straight Channels(Yıldız Teknik Üniversitesi, 2015) Çetkin, ErdalThis paper shows that a conductive domain which is subjected to heating from its bottom can be cooled with embedded microvascular cooling channels in it. The volume of the domain and the coolant are fixed. The actively cooled domain is mimicked from the human skin (which regulates temperature with microvascular blood vessels). The effect of the shape of cooling channels (sinusoidal or straight) and their locations in the direction perpendicular to the bottom surface on the peak and average temperatures are studied. In addition, the effect of pressure difference in between the inlet and outlet is varied. The pressure drop in the sinusoidal channel configurations is greater than the straight channel configurations for a fixed cooling channel volume. The peak and average temperatures are the smallest with straight cooling channels located at y = 0.7 mm. Furthermore, how the cooling channel configuration should change when the heat is generated throughout the volume is studied. The peak and average temperatures are smaller with straight channels than the sinusoidal ones when the pressure drop is less than 420 Pa, and they become smaller with sinusoidal channel configurations when the pressure drop is greater than 420 Pa. In addition, the peak and average temperatures are the smallest with sinusoidal channels for a fixed flow rate. Furthermore, the peak temperatures for multiple cooling channels is documented, and the multiple channel configurations promise to the smallest peak temperature for a fixed pressure drop value. This paper uncovers that there is no optimal cooling channel design for any condition, but there is one for specific objectives and conditions.Article Citation - WoS: 23Multiple Regression Analysis of Performance Parameters of a Binary Cycle Geothermal Power Plant(Elsevier Ltd., 2015) Karadas, Murat; Çelik, H. Murat; Serpen, Umran; Toksoy, MacitRegression analysis of a 7.35 MWe existing binary geothermal power plant is conducted using actual plant data to assess the plant performance. The thermo physical properties of geothermal fluid and ambient conditions, which are brine (geothermal water) temperature and flow rate, steam and NCGs (non-condensable gases) flow rates and ambient air temperature, directly affect power generation from a geothermal power plant. Generally, amount of power generated is calculated by deterministic formulations of thermodynamics. However, the data would be probabilistic because inputs may be measured by uncalibrated devices or some parameters may be neglected during the calculation. In these cases, the performance of power plant may be estimated by using regression analysis and then changing of plant performance may be monitored overtime. All measured parameters on DORA-1 Geothermal Power Plant from 2006 to 2012 and 49,411 hourly time series data are used in this study. A review of the available literature indicates this paper is the first study to focus on the prediction of power generation of a geothermal power plant by using multiple linear regression analysis. In this study, annual multiple linear regression models are developed to estimate the performance of a geothermal power plant. These models are tested by using classical assumptions of linear regressions and positive serial autocorrelation is found in all models. Autocorrelations are eliminated by using Orcutt-Cochran method. Although the performance model trends, from 2006 to 2008, are found to be close, the performance status of the plant is generally variable from year to year. According to annual regression models, since 2009, the plant performance started to decline with 270 kW(e) electricity generation capacity. The total degradation of the plant performance reached 760 kW(e) capacity by 2012. (C) 2014 Elsevier Ltd. All rights reserved.Article Citation - WoS: 8Citation - Scopus: 8Free Vibration Analysis of Damaged Composite Beams(Techno Press, 2015) Cünedioğlu, Yusuf; Beylergil, BertanIn this study, free vibration analyses of symmetric laminated cantilever and simply supported damaged composite beams are investigated by using finite element method (FEM). Free vibration responses of damaged beams are examined using Euler Bernoulli beam and classical lamination theories. A computer code is developed by using MATLAB software to determine the natural frequencies of a damaged beam. The local damage zone is assumed to be on the surface lamina of the beam by broken fibers after impact. The damaged zone is modeled as a unidirectional discontinuous lamina with 0 degrees orientations in this study. Fiber volume fraction (v(f)), fiber aspect ratio (L-f/d(f)), damage length (L-D) and its location (lambda/L), fiber orientation and stacking sequence parameters effects on natural frequencies are investigated. These parameters are affected the natural frequency values significantly.Article Citation - WoS: 28Citation - Scopus: 30Bone Marrow Stem Cells Adapt To Low-Magnitude Vibrations by Altering Their Cytoskeleton During Quiescence and Osteogenesis(TUBITAK, 2015) Demiray, Levent; Özçivici, EnginApplication of mechanical vibrations is anabolic to bone tissue, not only by guiding mature bone cells to increased formation, but also by increasing the osteogenic commitment of progenitor cells. However, the sensitivity and adaptive response of bone marrow stem cells to this loading regimen has not yet been identified. In this study, we subjected mouse bone marrow stem cell line D1-ORL-UVA to daily mechanical vibrations (0.15 g, 90 Hz, 15 min/day) for 7 days, both during quiescence and osteogenic commitment, to identify corresponding ultrastructural adaptations on cellular and molecular levels. During quiescence, mechanical vibrations significantly increased total actin content and actin fiber thickness, as measured by phalloidin staining and fluorescent microscopy. Cellular height also increased, as measured by atomic force microscopy, along with the expression of focal adhesion kinase (PTK2) mRNA levels. During osteogenesis, mechanical vibrations increased the total actin content, actin fiber thickness, and cytoplasmic membrane roughness, with significant increase in Runx2 mRNA levels. These results show that bone marrow stem cells demonstrate similar cytoskeletal adaptations to low-magnitude high-frequency mechanical loads both during quiescence and osteogenesis, potentially becoming more sensitive to additional loads by increased structural stiffness.