WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/11147/7150

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  • Article
    Citation - WoS: 7
    Citation - Scopus: 6
    Visceral Leishmaniasis Caused by Leishmania Tropica
    (Springer, 2023) Özbilgin, Ahmet; Tunalı, Varol; Çavuş, İbrahim; Vardarlı Tetik, Aslı; Dinç, Melike; Yalçın, Talat; Gündüz, Cumhur; Beyaz, Merve; Köse, Şükran
    PurposeIn Turkey, the main causative agent of visceral leishmaniasis (VL) is Leishmania. infantum and the main causative agent of cutaneous leishmaniasis (CL) is Leishmania tropica. In this study, we aimed to discuss the possible mechanisms, clinical aspects, and threat of visceralizing L. tropica.MethodsThis study includes seven cases of VL caused by L. tropica.Five patients were male (71%) and four were adults (57%).ResultsAll the VL patients complained of fever and splenomegaly. Fatigue, pancytopenia, and hepatomegaly were present in six patients each (86%), while weight loss and gastrointestinal system (GIS) symptoms were present in 5 patients (71%).ConclusionsIn this study, we have evaluated seven cases of visceralized L. tropica (VLT) in the context of the changing leishmaniasis epidemiology in Turkey. We have evaluated the possible mechanisms of visceralization; inter- and intraspecies genetic exchange with all the old world leishmaniasis agents present in the region, stress induced by inappropriate use of drugs, and possible ongoing adaptation mechanisms of Leishmania spp. The threat posed by VLT is significant as L. tropica is the most widespread and most common cause of leishmaniasis in Turkey. We do not know the vectorial capacity of the sand flies for the transmission of VLT strains or if these strains are in circulation in Turkey. Future studies should be carried out to investigate these issues as the transition of L. tropica from a mild disease-causing agent to a mortal one poses a significant public health concern for Turkey and Europe.
  • Article
    Citation - WoS: 27
    Citation - Scopus: 34
    Use of Abandoned Oil Wells in Geothermal Systems in Turkey
    (Springer, 2020) Kaplanoğlu, Murat A.; Baba, Alper; Gökçen Akkurt, Gülden
    Human beings have been benefiting from geothermal energy for different uses since the dawn of civilization in many parts of the world. One of the earliest uses of geothermal energy was for heating and it was used extensively by Romans in Turkey. The Aegean region is favored with a large number of thermal springs known since ancient times. However, it was in the twentieth century that geothermal energy was first used on a large scale for direct use applications and electricity generation. The country's installed heat capacity is 3322.3 MWt for direct use and 1347 MWe for power production. Also, many drilled wells to extract oil or natural gas were abandoned for various reasons in the southeast of Turkey. Some of the oil fields have heat content that can be used for geothermal energy. Some even have hot fluid in the reservoir. This paper presents an investigation into how to use geothermal energy in abandoned oil and natural gas wells. Methods used to generate geothermal energy from abandoned oil fields other than conventional geothermal energy production are examined. Downhole heat exchangers can be used to extract heat without producing geothermal fluid which decrease gas emissions to the atmosphere and energy need for reinjection, from the abandoned oil wells to generate electricity or direct use applications. Using this method, it is possible to use abandoned wells in southeastern Turkey where this energy improves the economy of the region.