WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7150
Browse
2 results
Search Results
Article Citation - Scopus: 1An Interestingness Measure for Knowledge Bases(Elsevier, 2023) Oğuz, Damla; Soygazi, FatihAssociation rule mining and logical rule mining both aim to discover interesting relationships in data or knowledge. In association rule mining, relationships are identified based on the occurrence of items in a dataset, while in logical rule mining, relationships are determined based on logical relationships between atoms in a knowledge base. Association rule mining has been widely studied in transactional databases, mainly for market basket analysis. Confidence has become the most widely used interesting measure to assess the strength of a rule. Many other interestingness measures have been proposed since confidence can be insufficient to filter negatively associated relationships. Recently, logical rule mining has become an important area of research, as new facts can be inferred by applying discovered logical rules. They can be used for reasoning, identifying potential errors in knowledge bases, and to better understand data. However, there are currently only a few measures for logical rule mining. Furthermore, current measures do not consider relations that can have several objects, called quasi-functions, which can dramatically alter the interestingness of the rule. In this paper, we focus on effectively assessing the strength of logical rules. We propose a new interestingness measure that takes into account two categories of relations, functions and quasi-functions, to assess the degree of certainty of logical rules. We compare our proposed measure with a widely used measure on both synthetic test data and real knowledge bases. We show that it is more effective in indicating rule quality, making it an appropriate interestingness measure for logical rule evaluation. & COPY; 2023 Karabuk University. Publishing services by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Article Citation - WoS: 4Citation - Scopus: 4Improving the Quality of Positive Datasets for the Establishment of Machine Learning Models for Pre-Microrna Detection(Informationsmanagement in der Biotechnologie e.V. (IMBio e.V.), 2017) Saçar Demirci, Müşerref Duygu; Allmer, JensMicroRNAs (miRNAs) are involved in the post-transcriptional regulation of protein abundance and thus have a great impact on the resulting phenotype. It is, therefore, no wonder that they have been implicated in many diseases ranging from virus infections to cancer. This impact on the phenotype leads to a great interest in establishing the miRNAs of an organism. Experimental methods are complicated which led to the development of computational methods for pre-miRNA detection. Such methods generally employ machine learning to establish models for the discrimination between miRNAs and other sequences. Positive training data for model establishment, for the most part, stems from miRBase, the miRNA registry. The quality of the entries in miRBase has been questioned, though. This unknown quality led to the development of filtering strategies in attempts to produce high quality positive datasets which can lead to a scarcity of positive data. To analyze the quality of filtered data we developed a machine learning model and found it is well able to establish data quality based on intrinsic measures. Additionally, we analyzed which features describing pre-miRNAs could discriminate between low and high quality data. Both models are applicable to data from miRBase and can be used for establishing high quality positive data. This will facilitate the development of better miRNA detection tools which will make the prediction of miRNAs in disease states more accurate. Finally, we applied both models to all miRBase data and provide the list of high quality hairpins.