WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7150
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Article Citation - WoS: 32Citation - Scopus: 39Fluorine-18 Fluorodeoxyglucose Pet-Ct for Extranodal Staging of Non-Hodgkin and Hodgkin Lymphoma(Turkish Society of Radiology, 2014) Ömür, Özgür; Baran, Yusuf; Oral, Aylin; Ceylan, Yeşim; 04.03. Department of Molecular Biology and Genetics; 04. Faculty of Science; 01. Izmir Institute of TechnologyPurpose We aimed to evaluate the role of fluorine-18 fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET-CT) involving care-dose unenhanced CT to detect extranodal involvement in patients with non-Hodgkin and Hodgkin lymphoma. Materials and Methods Lymphoma patients (35 Hodgkin lymphoma, 75 non-Hodgkin lymphoma) who were referred for 18F-FDG PET-CT imaging, following a diagnostic contrast-enhanced CT (CE-CT) performed within the last month, were included in our study. A total of 129 PET-CT images, and all radiologic, clinical, and pathological records of these patients were retrospectively reviewed. Results In total, 137 hypermetabolic extranodal infiltration sites were detected by 18F-FDG PET-CT in 62 of 110 patients. There were no positive findings by CE-CT that reflected organ involvement in 40 of 137 18F-FDG-positive sites. The κ statistics revealed fair agreement between PET-CT and CE-CT for the detection of extranodal involvement (κ=0.60). The organs showing a disagreement between the two modalities were the spleen, bone marrow, bone, and thyroid and prostate glands. In all lesions that were negative at CE-CT, there was a diffuse 18F-FDG uptake pattern in the PET-CT images. The frequency of extranodal involvement was 51% and 58% in Hodgkin and non-Hodgkin lymphoma patients, respectively. There was a high positive correlation between the maximum standardized uptake values of the highest 18F-FDG-accumulating lymph nodes and extranodal sites (r=0.67) in patients with nodal and extranodal involvement. Conclusion 18F-FDG PET-CT is a more effective technique than CE-CT for the evaluation of extranodal involvement in Hodgkin and non-Hodgkin lymphoma patients. PET-CT has a significant advantage for the diagnosis of diffusely infiltrating organs without mass lesions or contrast enhancement compared to CE-CT.Article Citation - WoS: 2Citation - Scopus: 3Effect of Voxel Size in Flow Direction on Permeability and Forchheimer Coefficients Determined by Using Micro-Tomography Images of a Porous Medium(Inderscience Enterprises Ltd., 2015) Uçar, Eren; Mobedi, Moghtada; Mobedi, Moghtada; Glatt, Erik; 03.10. Department of Mechanical Engineering; 03. Faculty of Engineering; 01. Izmir Institute of TechnologyThe permeability and Forchheimer coefficients of a porous medium, volcanic rock, are determined using micro-tomography images. A cubic volume in the middle of the images is extracted as REV (representative volume). The voids in the REV are discretised into anisotropic voxels using the commercial program of GeoDict. Seven computational domains with different voxel size in flow direction are generated. The velocity and pressure fields in the voids are obtained for Reynolds numbers ranging from 0.01 to 10. The obtained fields are used to determine the permeability and the Forchheimer coefficients. The performed calculations show that the nominal pore size changes with the voxel size in flow direction, however permeability and the Forchheimer coefficient approaches to the constant values.