WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7150
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Article Artificial Intelligence for Improving Thermal Comfort through Envelope Design in Residential Buildings: Recent Developments and Future Directions(Elsevier Science Sa, 2026) Bayraktar, Arda; Ekici, BerkEnvelopes are vital components for improving thermal comfort in almost all building typologies. Yet, the design and analysis of envelopes are complex, as they involve multiple aspects and various parameters, ensuring comfort standards. Improving thermal comfort in residential buildings is within the scope of researchers to suggest sustainable design alternatives that consider multiple performance aspects and design parameters. Previous review articles have focused on improving thermal performance in residential buildings from the perspective of envelope technology, materials, and design strategies. However, none of them investigated current developments using artificial intelligence (AI), which inevitably supports decision-making in complex circumstances for a sustainable built environment. This review examines the contribution of AI methods, which consist of metaheuristic optimization and machine learning algorithms as sub-branches, to envelope parameters. The paper systematically reviews 95 relevant works on AI, including early approaches, to provide a comprehensive overview of current developments, following PRISMA guidelines. The results showed that early applications considered conventional approaches to improve thermal comfort and energy performance, which mostly limit the results to specified cases. On the other hand, studies utilizing AI methods dealt with numerous parameters, allowing them to cope with complex envelope systems in a reasonable amount of time. The study addresses relevant research questions related to the trends, research methods, system types, AI methods, data types, and their relation to performance and envelope parameters. The study also provides actionable insight, underlining gaps and future works for utilizing machine learning methods in the reviewed research domain.Article Comparative Optimization of Hot Water and Citric Acid Extraction Methods for Sericin Recovery From Silk Cocoons: In Vitro Antioxidant and Antidiabetic Activities(Springer, 2026) Sincar, Bahar; Ozdemir, Feyza; Bicakci, Beyza Tutku; Erdem, Cansu; Yalcin, Dilek; Alamri, Abdulhakeem S.; Bayraktar, OguzSilk sericin, a hydrophilic protein derived from Bombyx mori cocoons, has attracted increasing interest due to its antioxidant, moisturizing, and enzyme-inhibitory properties. Efficient extraction is essential to preserve its biofunctional potential. In this study, sericin was extracted using hot water and 1.25% (w/v) citric acid using autoclave-based heating to achieve pressurized conditions above 100 degrees C. A Box-Behnken Response Surface Methodology (RSM) was applied to systematically evaluate the effects of extraction parameters (temperature and time) and to optimize five key response variables: yield, purity, molecular weight and polydispersity index (PDI), total antioxidant capacity (ABTS), and alpha-glucosidase inhibition activity. The results revealed that higher temperatures (125 degrees C) produced the maximum sericin yield, while moderate conditions (115 degrees C for 45 min) ensured better preservation of antioxidant and antidiabetic activities. Hot acid extraction resulted in significantly enhanced purity and enzymatic inhibition compared to hot water extraction. Sericin fractions above 7 kDa exhibited the strongest bioactivity, as reflected by lower IC50 values in both ABTS and alpha-glucosidase inhibition assays. The optimized hot water citric acid-based method yielded 24.00% sericin with 100.00% purity and an IC50 of 0.67 mg/mL for alpha-glucosidase inhibition. This study compares hot water and hot acid autoclave extractions using Box-Behnken design and evaluates their effects on sericin yield, purity, and bioactivities. Citric acid-based extraction produced higher purity and stronger alpha-glucosidase inhibition, while hot water extraction preserved antioxidant potential more effectively. These findings support the use of citric acid as an eco-friendly and scalable extraction agent and highlight the potential of sericin in biomedical and nutraceutical applications.Article A Novel ORC-PEM Integrated System for Sustainable Hydrogen Production from Low-Grade Waste Heat in Oil Refineries(Elsevier, 2025) Nazerifard, Reza; Mohammadpourfard, Mousa; Zarghami, RezaThis study presents an integrated multi-generation system for sustainable hydrogen production by harnessing low-grade waste heat from the overhead stream of the NHT unit's stripper column in an oil refinery. The proposed system integrates an ORC with a PEM electrolyzer, forming a novel energy solution that efficiently converts waste heat into clean hydrogen through electricity generation. A detailed model of the proposed system is developed, enabling a comprehensive assessment of its performance from thermodynamic, economic, and environmental viewpoints. At the same time, key operational parameters are optimized using the RSM-BBD method to minimize the hydrogen production cost, thereby enhancing the system's economic viability and practical implementation. The results demonstrated that the system achieves a yearly hydrogen production of 304.53 tons under optimized conditions, for 2.36 $/kg. The integrated system's overall energy and exergy efficiencies are calculated at 8.62 % and 33.43 %, respectively, demonstrating its high thermodynamic performance. Additionally, the system mitigates 3047 tons of CO2 annually by displacing conventional hydrogen production methods.Article Citation - WoS: 4Citation - Scopus: 4Optimization of Resource-Aware Parallel and Distributed Computing: a Review(Springer, 2025) Czarnul, Pawel; Antal, Marcel; Baniata, Hamza; Griebler, Dalvan; Kertesz, Attila; Kessler, Christoph W.; Rakic, GordanaThis paper presents a review of state-of-the-art solutions concerning the optimization of computing in the field of parallel and distributed systems. Firstly, we contribute by identifying resources and quality metrics in this context including servers, network interconnects, storage systems, computational devices as well as execution time/performance, energy, security, and error vulnerability, respectively. We subsequently identify commonly used problem formulations and algorithms for integer linear programming, greedy algorithms, dynamic programming, genetic algorithms, particle swarm optimization, ant colony optimization, game theory, and reinforcement learning. Afterward, we characterize frequently considered optimization problems by stating these terms in domains such as data centers, cloud, fog, blockchain, high performance, and volunteer computing. Based on the extensive analysis, we identify how particular resources and corresponding quality metrics are considered in these domains and which problem formulations are used for which system types, either parallel or distributed environments. This allows us to formulate open research problems and challenges in this field and analyze research interest in problem formulations/domains in recent years.Article Citation - WoS: 1Citation - Scopus: 1Effect of Soil Water Content Changes on the Behavior of Buildings Equipped With Single and Double Tuned Mass Dampers Subjected To Earthquakes(Springer Science and Business Media Deutschland GmbH, 2025) Roozbahan, M.; Turan, G.Tuned mass dampers (TMDs) are one of the structural control systems that have been frequently used in the last century. A TMD is designed according to the properties of the main system. In building applications, the substructure’s soil affects the response of buildings, especially in soft-type soils. Therefore, the soil properties should be included in the analysis and design of tuned mass dampers. However, the soil properties are not always identical and vary due to different factor changes such as soil water content changes. Unlike previous research, which typically assumes constant soil properties, this study incorporates the impact of soil water content changes, a key factor that can significantly alter soil behavior. This study aims to evaluate the effectiveness of optimized single and double tuned mass dampers (DTMDs) in response reduction of buildings considering the changes in the water content of soil. In this study, a metaheuristic-based optimization method is programmed to optimize TMDs and DTMDs for low-, mid-, and high-rise buildings considering soil-structure interaction (SSI). The efficiency of the optimized tuned mass dampers on the response reduction of buildings due to changes in soil water content is evaluated. According to the investigated results of 14 near-field earthquake simulations, it is concluded that the efficiency of the TMDs is significantly affected by changes in soil water content. Moreover, according to the result, the DTMD efficiency is slightly better than the TMD-controlled structure. © Springer Nature Switzerland AG 2025.Article Citation - WoS: 5Citation - Scopus: 6Sequence Identification and in Silico Characterization of Novel Thermophilic Lipases From Geobacillus Species(WILEY, 2023) Sürmeli, Yusuf; Tekedar, Hasan Cihad; Sanli-Mohamed, GulsahMicrobial lipases are utilized in various biotechnological areas, including pharmaceuticals, food, biodiesel, and detergents. In this study, we cloned and sequenced Lip21 and Lip33 genes from Geobacillus sp. GS21 and Geobacillus sp. GS33, then we in silico and experimentally analyzed the encoded lipases. For this purpose, Lip21 and Lip33 were cloned, sequenced, and their amino acid sequences were investigated for determination of biophysicochemical characteristics, evolutionary relationships, and sequence similarities. 3D models were built and computationally affirmed by various bioinformatics tools, and enzyme-ligand interactions were investigated by docking analysis using six ligands. Biophysicochemical property of Lip21 and Lip33 was also determined experimentally and the results demonstrated that they had similar isoelectric point (pI) (6.21) and T-m (75.5(degrees)C) values as T-m was revealed by denatured protein analysis of the circular dichroism spectrum and pI was obtained by isoelectric focusing. Phylogeny analysis indicated that Lip21 and Lip33 were the closest to lipases from Geobacillus sp. SBS-4S and Geobacillus thermoleovorans, respectively. Alignment analysis demonstrated that S144-D348-H389 was catalytic triad residues in Lip21 and Lip33, and enzymes possessed a conserved Gly-X-Ser-X-Gly motif containing catalytic serine. 3D structure analysis indicated that Lip21 and Lip33 highly resembled each other and they were alpha/beta hydrolase-fold enzymes with large lid domains. BAN Delta IT analysis results showed that Lip21 and Lip33 had higher thermal stability, compared to other thermostable Geobacillus lipases. Docking results revealed that Lip21- and Lip33-docked complexes possessed common residues (H112, K115, Q162, E163, and S141) that interacted with the substrates, except paranitrophenyl (pNP)-C10 and pNP-C12, indicating that these residues might have a significant action on medium and short-chain fatty acid esters. Thus, Lip21 and Lip33 can be potential candidates for different industrial applications.Article Citation - WoS: 4Citation - Scopus: 4Optimizing the Dispersion of Calcium Phosphate Nanoparticles for Cellular Studies Using Statistical Design of Experiments(Elsevier, 2023) Önder, Anıl Can; Tomak, Aysel; Öksel Karakuş, CeydaThe in vitro experimentation of ceramic nanoparticles often requires their dispersion in liquid media without causing particle clumps or deteriorating sample integrity. However, the dispersion of nanoparticles using the available protocols rarely leads to stable and uniform dispersions which, in turn, raises concerns about the validity, repeatability and comparability of the findings observed in vitro. Moreover, the ability to control the final dispersion quality of ceramic nanoparticles is an essential step to obtaining optimized nanoceramic materials with desired functionality and to enhancing their performance in subsequent applications. While the need to have a comprehensive guideline for the dispersion of nanoparticles has led to several published documents and protocols, the dispersion methodology of ceramic nanoparticles and the relative contribution of the experimental parameters to the quality of resulting dispersion are still not clear. Here, we employed the statistical design of experiment (DoE) approach to systematically assess the magnitude and source of variation in dispersion quality of two different ceramic nanoparticles, hydroxyapatite and tricalcium phosphate. Using the first-order Plackett-Burman Design (PBD), nanoparticle concentration, pH and the presence of an additive were identified as the most critical factors influencing the resulting hydrodynamic size and zeta potential of the ceramic nanoparticles. Optimization using a second-order Central Composite Design (CCD) yielded a set of quadratic regression equations that were used to predict the hydrodynamic size or zeta potential of ceramic nanoparticles with high accuracy (R2, 0.88–0.92). The results of PBD screening and CCD optimization experiments were employed to prepare nanoparticle dispersions of different quality, which were then used to compare the effect of aggregation on the viability of human osteosarcoma (SaOS-2) cells. Overall, the results of this study provided insight into the role that various experimental parameters play in the colloidal stability and dispersion of ceramic nanoparticles. © 2023Article Citation - WoS: 11Citation - Scopus: 12An Improved Passive Tuned Mass Damper Assisted by Dual Stiffness(Elsevier, 2023) Roozbahan, Mostafa; Turan, GürsoyA tuned mass damper (TMD) is one of the oldest and most commonly used passive control devices attached to structures to absorb lateral loads of energy from main systems. In the last decades, several novel tuned mass dampers have been designed to increase the performance of TMDs in decreasing the structural responses during excitation vibrations. Moreover, several formulations and numerical optimization methods have been developed to optimize the TMDs parameters. This paper proposes a novel passive tuned mass damper with dual stiffness (DSTMD). The DSTMD includes mass, primary and secondary springs, dashpot, and motion limiting chamber. The performance of DSTMDs depends on their properties such as mass, primary and secondary stiffness, damping coefficient, and the length of the motion limiting chamber. Thus, a metaheuristic optimization algorithm, called the Mouth Brooding Fish algorithm, was used to optimize the DSTMDs parameters. The effectiveness of the optimum DSTMD on two different linear ten-story structures under several earthquakes has been studied and compared with the effectiveness of classical optimum TMDs. According to the study, optimum DSTMDs generally show better effects for certain excitations, and as an average performance, they are superior compared to the classical optimum TMDs in reducing maximum displacement of the buildings. At last, structural yielding is considered, and the performance analysis on this structure shows that the DSTMD has a superior effect in reducing the maximum displacement and is among the best methods for the calculated absolute yielding amount.Article Citation - WoS: 22Citation - Scopus: 22Multiparameter-Based Product, Energy and Exergy Optimizations for Biomass Gasification(Elsevier, 2021) Çağlar, Başar; Tavşancı, Duygu; Bıyık, EmrahThe thermodynamic modelling of biomass gasification was studied by using Gibbs free energy minimization approach. Different from the studies using the same approach, the simultaneous presence of all gasifying agents (air, H2O and CO2) was considered and a multiparameter optimization was applied to determine the synergetic effect of gasifying agents for hydrogen, syngas with a specific H2/CO ratio and methane production. The performance of gasification was assessed by using technical and environmental performance indicators such as product yields, cold gas efficiency, exergy efficiency, CO2 emission and the heat requirement of the gasifier. The results show that the simultaneous presence of gasifying agents does not create considerable changes in syngas yield, H2 yield, methane yield, CGE and exergy efficiency while it allows to tune the H2/CO ratio and the heat requirement of the gasifier. The highest syngas yield is observed at T > 1100 K and 1 bar and when SBR > 0.5 and/or CBR > 0.8 with the absence of air, at which CGE changes between 114% and 122% while exergy efficiency is between 77% and 86%. The results prove that CO2 offers several advantages as a gasifying agent and suggests that CO2 recycling from gasifier outlet is a useful option for the biomass gasification.Article Citation - WoS: 1Citation - Scopus: 1Approaches To Optimization for Movable Shading Systems: a Review of Optimization Methods and Tools(Znack Publishing House, 2021) Keskinel, Yeşim; İlal, Mustafa EmreStudies show that movable shading systems have lots of benefits for building performance. Minimizing energy consumption and maximizing daylight usage are natural expectations when using these systems. To find optimal solutions for these systems, different methods have been used. Today, optimization methods are used to solve this problem. In the literature, there are few studies about optimization of movable shading systems. This paper aims to identify different movable shading systems, optimization types, and computational optimization tools that are used. Research findings and future projections based on the reviewed papers are summarized.