WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7150
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Article Nanostructured Ox-MWCNT-Ppy-Au Electrochemical Sensor for Ultralow Detection of Retrorsine and Evaluation of Its Cytotoxic Effects on Liver Cells(Taylor & Francis Ltd, 2025) Akturk, Ezgi Zekiye; Njjar, Muath; Ata, Melek Tunc; Kaya, Ahmet; Akdogan, Abdullah; Onac, CananThis study presents the development of a novel retrorsine (RTS)-imprinted sensor utilizing oxidized multi-walled carbon nanotubes (Ox-MWCNTs), polypyrrole (PPy), and gold nanoparticles (AuNPs), employing square wave voltammetry for the sensitive and selective detection of RTS which causes oxidative-stress and DNA damage. The fabricated Ox-MWCNT-PPy-AuNP sensor demonstrated a surface-area of (0.218 cm2) is 4.25 times larger than a bare glassy carbon electrode, with a low charge transfer resistance (10.9 Omega), enhancing electron transfer kinetics. The sensor showed excellent sensitivity in detecting retrorsine, with a limit of detection of 0.035 nM in synthetic matrices and -0.030 nM in HepaRG cell culture medium. Toxicity assays in HepaRG cells revealed dose-dependent oxidative-stress, with glutathione levels decreasing from 23.08 +/- 0.21 mu mol/109 to 21.21 +/- 0.02 mu mol/109 at 35 mu M retrorsine. Concurrently, GSSG levels increased from 1.32 +/- 0.26 mu mol/109 to 2.22 +/- 0.02 mu mol/109. DNA-damage assessed via comet assay, showed significant increases in tail-moment (2.53 mu m) and tail-migration (16.13 mu m). Oxidative DNA-damage, indicated by 8-OHdG levels, increased significantly from 0.29 +/- 0.02 ng.mL- (control) to 0.47 +/- 0.07 ng.mL- at 35 mu M retrorsine. These findings demonstrate the sensor's effectiveness for retrorsine detection and its applicability in toxicological studies. The integration of nanomaterial engineering and molecular imprinting provides a highly sensitive, selective, and eco-friendly solution for monitoring toxic agents and assessing their biological impacts.Article Citation - WoS: 2Citation - Scopus: 2Charting the Landscape of Design Cognition: Bridging the Gap Between Design Cognition and Cognitive Science(Taylor & Francis Ltd, 2025) Ata, F. Zeynep; Dogan, FehmiThis study examines the trajectory of cognitive studies on design processes (DesCog), charting its scientific landscape and interactions with cognitive science (CogSci). First, the study delineates the boundaries of DesCog within all published scholarly works. The analysis indicates that DesCog is a focused field with lesser impact on other fields, showing divergent bibliographic positions and connections for 'design cognition' and 'design thinking'. Second, the longitudinal evolution of DesCog is identified as gradually becoming more diverse and more connected. Third, DesCog's foundational connections to CogSci demonstrate that the relationship is spontaneous rather than following 'generalising interdisciplinarity' aims. The analysis indicates a unidirectional flow from CogSci to DesCog, with occasional reciprocal interactions. The volume and diversity of CogSci literature cited by DesCog appear narrow, and most cited publications are based on the information-processing theory of cognition. Fourth, the study identifies common themes at the intersection of two fields, demonstrating that creativity has been a focal theme for both since earlier studies. Finally, the individual impact of CogSci researchers on DesCog highlights the significance of Simon and Newell's influence. The study contributes to reflections on DesCog's knowledge production, underlining unidirectional knowledge flows from CogSci to DesCog and partial theoretical connections within the field.Article Citation - WoS: 1Citation - Scopus: 1Adaptive Reuse of Industrial Heritage in Crises Zones: the Soap Factories in the Levant(Taylor & Francis Ltd, 2025) Saifi, Yara; Zawawi, Zahraa; Yuceer, HulyaThis paper articulates critical considerations for policies related to the adaptive reuse of industrial heritage, particularly in contexts affected by crises, such as conflicts, wars, and natural disasters using the soap factories of the Levant as a case study. It critically investigates the role of adaptive reuse in conserving industrial heritage buildings impacted by crises. The Levant provides a unique context for examining the intersection of cultural heritage and resilience; soap factories, reflective of the region's olive-oil-rich history and industrial legacy dating back to the 18th century, symbolise the conservation challenges and opportunities posed by ongoing regional conflict. The study systematically analyses existing literature on adaptive reuse and questions conventional paradigms in crisis environments, particularly the suitability of standard transformations such as converting industrial heritage into museums or exhibition spaces. Instead, it aims to broaden the dialogue on adaptive reuse by offering context-sensitive policy recommendations. These strategies balance the imperatives of heritage conservation, sustainable development, and contemporary community demands, contributing to a nuanced understanding of industrial heritage preservation in crisis-affected regions.Article Citation - WoS: 1Citation - Scopus: 2Co-Designing of Public Space for Urban Design Students Using Citizen-Generated Data(Taylor & Francis Ltd, 2025) Ozden, Pelin; Muller, Johannes; Velibeyoglu, KorayThis study describes the co-design process, which includes the citizens' spatial experiences, needs, and wishes, through participatory digital design tools in urban design. The paper draws on a case study for co-design practices for leftover public space; Re-shaping K & uuml;& ccedil;& uuml;k Park urban void in Bornova, Izmir, Turkey. The methodology used in this study is a further improvement of 'Citizen Design Science' and its tool Qua-Kit (a map-based e-participation tool), which originated from Future Cities Laboratory (FCL) in ETH Zurich. The toolkit allows users to move geometries in given urban spaces and enables non-expert participants to express their ideas for the urban area through design. Departing from conventional urban design approaches, the shaping of the urban realm became a democratic process in which all stakeholders participated as co-designers. The study utilises objective and subjective design data, offering a novel perspective on urban design education and the profession. The educational experiment showed that participants could contribute their experiences and opinions through active design tools and the development process in co-designing public spaces.Article Estimating the Impact of New Rail Service on Travel Behaviour of Current Bus Passengers Using Smart Card Data(Taylor & Francis Ltd, 2025) Kesmez, Firat Enver; Uz, Volkan EmreEstimating the impact of new public transportation infrastructure is essential for network efficiency. This study uses one weekday of smart card data to estimate the impact of planned rail service on bus passengers' travel behaviour. Using the metro extension project in the metropolitan city of & Idot;zmir, T & uuml;rkiye as a case study, we developed a methodology involving a trip chaining algorithm, inter-route relationship analysis, and travel time calculations. Our estimations show that about 55% of bus passengers are shifting due to a significant reduction in travel time, while 20% find using the extension impractical, necessitating continued bus service. The rest of the bus passengers can potentially be inclined to use new infrastructure by improving the transfer conditions, underlining the potential focus for planners to increase the use of the new service. Our research offers valuable insights for policymakers and planners, ensuring the adaptation of transportation systems to meet changing travel behaviour.Article Citation - WoS: 2Citation - Scopus: 2The Unlimited Joy, 'once You Start You Can't Stop': Masculinity in Domestic Technology Commercials in Turkey(Taylor & Francis Ltd, 2024) Karaosmanoglu, Defne; Ata, Leyla Bektas; Emgin, BaharRecently, studies have begun examining men's interaction with domestic space to explore changing forms of masculinity and domesticity, arguing that housework has become a leisure activity for men, with domestic technologies serving as tools (toys) for them to engage with. In this article, we explore how men in Turkish television commercials of domestic technologies are portrayed and how these portrayals construct and reconstruct discourses of domesticity and masculinity. We aim to understand men's relationship with masculinity, home and domestic work in these commercials. Alongside leisure and fun, we explore the construction of discourses of masculinity and domesticity through specific themes such as the naughty scientist, the self-seeking purchaser, and the flirtatious chef. We argue that seeing more men on screen does not democratise domesticity since the equal share of workload at home is still far from being realised even in these portrayals. We also argue that domesticity is aestheticized with the participation of men and technology. Finally, women are used as instruments by men in reconstructing their masculinity through heterosexuality.Article Stabilisation of Linear Waves With Inhomogeneous Neumann Boundary Conditions(Taylor & Francis Ltd, 2024) Ozsari, Turker; Susuzlu, IdemWe study linear damped and viscoelastic wave equations evolving on a bounded domain. For both models, we assume that waves are subject to an inhomogeneous Neumann boundary condition on a portion of the domain's boundary. The analysis of these models presents additional interesting features and challenges compared to their homogeneous counterparts. In the present context, energy depends on the boundary trace of velocity. It is not clear in advance how this quantity should be controlled based on the given data, due to regularity issues. However, we establish global existence and also prove uniform stabilisation of solutions with decay rates characterised by the Neumann input. We supplement these results with numerical simulations in which the data do not necessarily satisfy the given assumptions for decay. These simulations provide, at a numerical level, insights into how energy could possibly change in the presence of, for example, improper data.Article Citation - WoS: 2Citation - Scopus: 3Comprehensive Analysis of Botanical Origin and Amino Acid Composition of Bee Pollen Samples From Various Regions of Turkey(Taylor & Francis Ltd, 2024) Mutlu, Ceren; Candal-Uslu, Cihadiye; Ozkok, Asli; Koc, Andac; Ozhanli, Hazal; Akdeniz, Gokhan; Erbas, MustafaThis study aimed to investigate the botanical diversity in bee pollen and amino acid composition of Turkish bee pollen samples collected from different regions. The monofloral bee pollen samples belonged to three different plant families: Asteraceae, Fabaceae, and Ranunculaceae. Additionally, Agean, Central Anatolian, Black Sea, and Marmara Regions have monofloral bee pollen samples with higher than 85% pollen frequency. The free amino acid (FAA) composition and content of the bee pollen samples were analyzed, with the essential amino acids comprising 13.13-18.28% of the total amino acid content. The Central Anatolian region displayed the highest ratio of essential amino acids, and the Aegean region exhibited a more diverse profile of FAA. Principal Component Analysis was performed to evaluate the variation in the data, with the eigenvalues of the two factors explaining 68.58% of the total variability. Moreover, cluster analysis revealed distinct dendrograms based on palynological characteristics and FAA composition.Article Citation - WoS: 4Citation - Scopus: 3Assessment of Soil Erosion and Sediment Delivery Ratio in the Arghandab Catchment, Kandahar Province, Afghanistan by Using Gis-Based Rusle Method(Taylor & Francis Ltd, 2024) Ansari, Ahmad; Tayfur, Gokmen; Mohammadi, ShahinA significant proportion of Arghandab Catchment in Kandahar Province, Afghanistan has been under potential degradation threat due to soil erosion. This study assessed the extent of soil erosion and estimated the sediment delivery ratio (SDR) in the catchment by employing the Revised Universal Soil Loss Equation (RUSLE), utilizing the Geographic Information System (GIS) and the Remote Sensing (RS) techniques. Data, related to rainfall erosivity (R factor), soil erodibility (K factor), slope length and steepness (LS factor), cover management (C factor), and support practices (P factor), employed for the RUSLE model were processed using the GIS tools and R-Studio software. Average RUSLE factor values estimated in the studied area ranged from 51.8 to 124 MJ mm ha-1 h-1 year-1, 0.03725 t ha h ha-1 MJ-1 mm-1, 9.2, 0.445, and 0.75 for R, K, LS, C, and P factors, respectively. The results revealed that the average annual soil loss from the catchment was 6.81 t ha-1 yr-1, ranging from 0.002 t ha-1 yr-1 in the flat areas up to 94.7 t ha-1 yr-1 in the hilly and mountainous regions. Soil classes of slight, moderate, high, very high, severe, and very severe covered areas of 20.1% (263,542.3 ha), 12.2% (160,286.5 ha), 22.8% (298,740.6 ha), 20.3% (265,546.8 ha), 17.6% (231,224.4 ha) and 6.9% (90,879.9 ha), respectively. The computed SDR for Dahla Reservoir located in the catchment was found to be in between 24.2% and 36%. LS factor was identified as the most crucial variable associated with soil erosion. The findings from this study can be applied when designing effective conservation strategies in the management of erosion and water management.