WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/11147/7150

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Department: search.filters.department.İzmir Institute of Technology. RectorateScopus Q: search.filters.scopusQuartile.Q1

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Now showing 1 - 10 of 166
  • Article
    Governing Authority Through Bureaucracy: Conflicts Over Bureaucratic Cadres and the Rise of Authoritarianism in the Late Ottoman Empire (1908-1913)
    (Routledge Journals, Taylor & Francis Ltd, 2024) İlter, Mustafa
    This article presents a historical analysis of how internal power struggles and conflicts among state actors can foster the development of authoritarian systems, particularly when a political network gains exclusive control over the bureaucratic apparatus through its authority over appointments and dismissals. Focusing on the intricate power struggles and factional rivalries surrounding gubernatorial appointments between 1908 and 1913, this article aims to provide an alternative approach to understanding how the Committee of Union and Progress (CUP) became the dominant governing force within the state apparatus, enabling it to pursue an authoritarian agenda.
  • Article
    Citation - WoS: 2
    Citation - Scopus: 3
    Nkx3.1 Expression Contributes To Epithelial-Mesenchymal Transition of Prostate Cancer Cells
    (American Chemical Society, 2023) Saydullaeva, Iroda; Debeleç Bütüner, Bilge; Korkmaz, Kemal Sami
    Studies demonstrate that inflammation synergizes with highgrade aggressive prostate tumor development and ultimately metastatic spread, in which a lot of work has been done in recent years. However, the clear mechanism of inflammation inciting prostate cancer remains largely uncharacterized. Our previous study has shown that the conditioned media (CM)-mediated LNCaP cell migration is partially correlated with the loss of expression of the tumor suppressor NKX3.1. Here, we continue to investigate the inflammation-mediated migration of prostate cancer cells, and the role of NKX3.1 in this process to gain insights into cell migration-related changes comprehensively. Earlier, the model of inflammation in the tumor micro environment have been optimized by our research group; here, we continue to investigate the time-dependent effect of CM exposure together with NKX3.1 changes, in which we observed that these changes play important roles in gaining heterogeneous epithelial-to-mesenchymal transition (EMT) phenotype. Hence, this is an important parameter of tumor progression; we depleted NKX3.1 expression using the CRISPR/Cas9 system and examined the migrating cell clusters after exposure to inflammatory cytokines. We found that the migrated cells clearly demonstrate reversible loss of E-cadherin expression, which is consistent with subsequent vimentin expression alterations in comparison to control cells. Moreover, the data suggest that the AR mediated transcriptional program also contributes to mesenchymal-to-epithelial transition (MET) in prostate cancer progression. Furthermore, the quantitative proteomic analysis showed that migrated subpopulations from the same cell line presented different phenotypes in which the proteins overexpressed are involved in cell metabolism and RNA processing. According to KEGG pathway analysis, the ABC transporters were found to be the most significant. Thus, the dynamic process of cellular migration favors diverse genetic compositions under changing tumor microenvironments. The different levels of invasiveness are supported by shifting the cells in between these EMT and MET phenotypes.
  • Article
    Citation - WoS: 20
    Nuclear Modification of Y States in Ppb Collisions at Root S-Nn=5.02 Tev
    (Elsevier, 2022) Tumasyan, A.; Karapınar, Güler
    Production cross sections of Y(1S), Y(2S), and Y(3S) states decaying into mu(+)mu(-) in proton-lead (pPb) collisions are reported using data collected by the CMS experiment at root S-NN= 5.02 TeV. A comparison is made with corresponding cross sections obtained with ppdata measured at the same collision energy and scaled by the Pb nucleus mass number. The nuclear modification factor for Y(1S) is found to be R-pPb(Y(1S)) = 0.806 +/- 0.024 (stat)+/- 0.059 (syst). Similar results for the excited states indicate a sequential suppression pattern, such that R-pPb(Y(1S)) > R-pPb(Y(2S)) > R-pPb(Y(3S)). The suppression of all states is much less pronounced in pPbthan in PbPbcollisions, and independent of transverse momentum p(T)(Y) and center-of-mass rapidity y(CM)(Y) of the individual Y state in the studied range p(T)(Y) < 30GeV/c and |y(CM)(Y)| < 1.93. Models that incorporate final-state effects of bottomonia in pPb collisions are in better agreement with the data than those which only assume initial-state modifications. (c) 2022 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
  • Article
    Citation - WoS: 1
    Citation - Scopus: 9
    Search for Heavy Resonances Decaying To Z (ν Ν ¯)v (q Q ¯ ′) in Proton-Proton Collisions at S =13 Tev
    (American Physical Society, 2022) Karapınar, Güler; CMS Collaboration
    A search is presented for heavy bosons decaying to Z(νν¯)V(qq¯′), where V can be a W or a Z boson. A sample of proton-proton collision data at s=13 TeV was collected by the CMS experiment during 2016-2018. The data correspond to an integrated luminosity of 137 fb-1. The event categorization is based on the presence of high-momentum jets in the forward region to identify production through weak vector boson fusion. Additional categorization uses jet substructure techniques and the presence of large missing transverse momentum to identify W and Z bosons decaying to quarks and neutrinos, respectively. The dominant standard model backgrounds are estimated using data taken from control regions. The results are interpreted in terms of radion, W′ boson, and graviton models, under the assumption that these bosons are produced via gluon-gluon fusion, Drell-Yan, or weak vector boson fusion processes. No evidence is found for physics beyond the standard model. Upper limits are set at 95% confidence level on various types of hypothetical new bosons. Observed (expected) exclusion limits on the masses of these bosons range from 1.2 to 4.0 (1.1 to 3.7) TeV. © 2022 CERN.
  • Erratum
    Citation - WoS: 3
    Citation - Scopus: 7
    Searches for Long-Lived Charged Particles in Pp Collisions at Root S = 7 and 8 Tev (vol 07, 122, 2013)
    (Springer, 2022) Karapınar, Güler; CMS Collaboration
    [No abstract available]
  • Correction
    Citation - WoS: 1
    Citation - Scopus: 2
  • Correction
    Citation - Scopus: 3
  • Article
    Citation - WoS: 28
    Citation - Scopus: 33
    Search for Low-Mass Dilepton Resonances in Higgs Boson Decays To Four-Lepton Final States in Proton-Proton Collisions at Root S=13 Tev
    (Springer, 2022) Karapınar, Güler; CMS Collaboration
    A search for low-mass dilepton resonances in Higgs boson decays is conducted in the four-lepton final state. The decay is assumed to proceed via a pair of beyond the standard model particles, or one such particle and a Z boson. The search uses proton-proton collision data collected with the CMS detector at the CERN LHC, corresponding to an integrated luminosity of 137 fb(-1), at a center-of-mass energy root s = 13 TeV. No significant deviation from the standard model expectation is observed. Upper limits at 95% confidence level are set on model-independent Higgs boson decay branching fractions. Additionally, limits on dark photon and axion-like particle production, based on two specific models, are reported.
  • Article
    Citation - WoS: 3
    Citation - Scopus: 5
    Search for Strongly Interacting Massive Particles Generating Trackless Jets in Proton-Proton Collisions at Root S=13 Tev
    (Springer, 2022) Karapınar, Güler; CMS Collaboration
    A search for dark matter in the form of strongly interacting massive particles (SIMPs) using the CMS detector at the LHC is presented. The SIMPs would be produced in pairs that manifest themselves as pairs of jets without tracks. The energy fraction of jets carried by charged particles is used as a key discriminator to suppress efficiently the large multijet background, and the remaining background is estimated directly from data. The search is performed using proton-proton collision data corresponding to an integrated luminosity of 16.1 fb(-1), collected with the CMS detector in 2016. No significant excess of events is observed above the expected background. For the simplified dark matter model under consideration, SIMPs with masses up to 100 GeV are excluded and further sensitivity is explored towards higher masses.
  • Article
    Citation - WoS: 9
    Citation - Scopus: 13
    Probing Charm Quark Dynamics Via Multiparticle Correlations in Pb-Pb Collisions at Root S(nn)=5.02 Tev
    (Amer Physical Soc, 2022) Tumasyan, A.; Karapınar, Güler
    Multiparticle azimuthal correlations of prompt D-0 mesons arc measured in Pb-Pb collisions at a nucleon-nucleon center-of-mass energy of root s(NN) = 5.02 TeV. For the first time, a four-particle cumulant method is used to extract the second Fourier coefficient of the azimuthal distribution (v(2)) of D-0 mesons as a function of event centrality and the D-0 transverse momentum. The ratios of the four-particle v(2) values to previously measured two-particle cumulant results provide direct experimental access to event-by-event fluctuations of charm quark azimuthal anisotropies. These ratios are also found to be comparable to those of inclusive charged particles in the event. However, hints of deviations are seen in the most central and peripheral collisions. To investigate the origin of flow fluctuations in the charm sector, these measurements are compared to a model implementing fluctuations of charm quark energy loss via collisional or radiative processes in the quark-gluon plasma. These models cannot quantitatively describe the data over the full transverse momentum and centrality ranges, although the calculations with collisional energy loss provide a better description of the data.