TR Dizin İndeksli Yayınlar / TR Dizin Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7149
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Article Seismic Risk Prioritization of Stone Masonry Building Stock in Urla Peninsula Based on Rapid Assessment Techniques(Turkish Chamber of Civil Engineers, 2026) Karavin, Y.S.; Akdag, N.; Demir, U.This study aims to investigate seismic risk of stone masonry buildings in the Urla Peninsula, a region of historical and architectural significance within İzmir, Türkiye. A total of 100 stone masonry buildings were surveyed and documented with a focus on their architectural characteristics, including construction techniques, material types, structural configurations, and age. Data on the properties of all surveyed buildings are provided in an open-access database. Based on the survey, multiple rapid seismic performance assessment methods were applied to evaluate the vulnerability of these structures. These included: i) FEMA P-154 Rapid Visual Screening, ii) Provisions for the Seismic Risk Evaluation of Existing Buildings under Urban Renewal Law (RBTE-2019), iii) Seismic Vulnerability Index for Vernacular Architecture (SVIVA), and iv) the Masonry Quality Index (MQI). The comparative use of different methods is intended to investigate the relative influence of parameters shaping the seismic performance of the masonry building stock rather than to align their scores. The outcomes of this research are expected to contribute to the current risk mitigation efforts for stone masonry buildings in İzmir, thereby supporting regional seismic resilience planning. © 2026, Turkish Chamber of Civil Engineers. All rights reserved.Article Experimental Study of Evolution of Breach Resulting From Piping at Upper Part of Earth-Fill Dam(Turkish Chamber Civil Engineers, 2025) Guney, Mehmet Sukru; Tayfur, Gokmen; Bor, Asli; Okan, Merve; Dumlu, Emre; Aklık, PelinPiping and overtopping are the most important causes of earth-fill dam failure. Such dams may erode under seepage, causing a reduction in the structural strength. The aim of this study was to investigate the temporal evolution of the breach and flow rate from the breach resulting from the piping in earth-fill dams. The experiments were carried out at Hydraulics Laboratory of Civil Engineering Department of İzmir University of Economics. The dam was constructed by using a mixture consisting of 85 % sand and 15 % fine (low plasticity clay). In the first scenario a circular tunnel with a diameter of 2 cm was created along the centreline at 6 cm below the dam crest whereas in the second one it was located at the upper edge. Six cameras at different locations recorded the evolution of the progress of the breach formation. The pump flow rate was measured by magnetic flow meter, and the continuity equation was used to calculate the flow rate values from the breach. The time-varied values of the total breach areas were determined using the Gauss Area formula. The image processing method was also applied in the determination of the breach areas. The time-dependent changes of water depth in the channel were also recorded. The obtained experimental findings are presented and commented, together with the universal dimensionless curves. The failure of the dams occurred mainly because of the head cut erosion developed from downstream to upstream. When breaching started, the orifice flow was converted to open channel flow where breach bottom behaved like a broad crested weir. In the second scenario, the rigid lateral side considerably influenced the flow rate and the development of the breach. The peak flow rate corresponding to the first scenario was found approximately 2.3 times greater than that of the second one. The maximum values of all the breach parameters were reached earlier in the case of the seepage along the centerline. The ratios between the values corresponding to the first and the second scenarios were found as 3.25 and 1.75 for maximum breach areas at downstream and at upstream sides, respectively. These ratios were 2.44 and 1.37 for the average breach widths at downstream and upstream sides, respectively. A very good agreement was found between the area values obtained from Gauss area method and image processing technique, in both scenarios. This fact demonstrated that either of these two approaches can be used to determine the time-dependent breach areas. These experimental findings provide the opportunities for the calibration and validation of the numerical models used in the relevant numerical investigations. This study also offers guidance for the strategies concerning emergency action plans related to the failure of homogeneous earth-fill dams when the piping starts at upper part of the homogeneous earth-fill dams.Article Gypsophila Eriocalyx Roots Inhibit Proliferation, Migration, and Tgf-Β Signaling in Melanoma Cells(Walter de Gruyter GmbH, 2025) Azbazdar, Yagmur; Ozhan, Gunes; Helvacioglu, SelinObjectives: Melanoma is a highly malignant and serious form of skin cancer. In addition to the standard treatments, complementary approaches, including phytotherapy, are also used to alleviate symptoms and improve patient well- being. This study aims to investigate the anticancer effects of Gypsophila eriocalyx (GE), an endemic species from Türkiye, on melanoma cells. We set out to determine the efficacy of GE in inhibiting melanoma cell proliferation, migration, and growth, and to explore its underlying mechanisms. Methods: We examined the impact of GE on the prolifera- tion of two melanoma cell lines, Malme-3M and SK-MEL-28, and assessed its developmental toxicity in zebrafish em- bryos. Next, we evaluated GE’s influence on colony forma- tion and wound healing in melanoma cells, as well as its ability to induce apoptosis and affect the TGF-β/Smad signaling pathway, by measuring pathway reporter activity and target gene expression. Results: GE inhibited cell proliferation in melanoma cell lines at concentrations 104 to 488 times lower than those required for normal non-malignant L929 fibroblast cells. In zebrafish embryos, GE demonstrated developmental toxicity only at concentrations above 50 μg/mL. GE treatment significantly impaired the colony formation and wound healing abilities of melanoma cells, indicating reduced pro- liferation and migration. Moreover, GE induced apoptosis in melanoma cells and inhibited the TGF-β/Smad signaling pathway, as evidenced by decreased pathway reporter activity and target gene expression. Conclusions: This study highlights the potential of GE as a novel therapeutic agent in melanoma treatment by demon- strating its ability to inhibit tumor growth and progressionArticle Citation - WoS: 1Citation - Scopus: 1Investigation of Flow and Heat Transfer Performance of Gyroid Structure as Porous Media(Turkish Soc Thermal Sciences Technology, 2024) Genc, Alper Mete; Karadeniz, Ziya HaktanThere are active and passive methods used to improve heat transfer. One of the passive methods is utilising porous media with high heat transfer surface area. Porous media are divided into two groups: regular and irregular structures. One of the regular structures is triply periodic minimal surfaces (TPMS), which have been studied quite frequently recently. In this study, heat transfer and flow analysis of a Gyroid geometry, one of the most used TPMS in the literature, is investigated numerically considering the conjugate heat transfer conditions. A single porosity is considered (epsilon = 0.6), and aluminium, ceramic and PLA are selected for the heat exchanger material to examine the temperature change in the heat exchanger. To understand the different flow characteristics, Reynolds numbers are assumed to be 19.12, 95.61 and 172.09. The fluid inlet temperature is assumed to be constant at 298.15 K, and the initial temperature of the heat exchanger is assumed to be constant at 278.15 K to be consistent with the regenerative heat recovery temperature difference in ventilation standards. Nusselt numbers under different operating conditions are compared, and it is the ceramic material with low thermal diffusivity is at the highest level despite its low thermal conductivity. At the highest Reynolds number, it provided approximately 6% better heat transfer than the aluminium heat exchanger.Article Citation - Scopus: 1Anomalous Crustal Structure Beneath the Örenli-Eğiller Depression Zone, Inferred From Magnetotelluric Studies, Western Anatolia, Türkiye(TÜBİTAK - Türkiye Bilimsel ve Teknolojik Araştırma Kurumu, 2024) Chandrasekharam, Dornadula; Raju, K.; Subba Rao, P.B.V.; Baba, AlperIn Türkiye, the prevalence of high radiogenic granites makes them ideal locations for initiating enhanced geothermal system (EGS) projects. One such occurrence of these granites is observed in the Kozak area of the Bergama region. To assess the energy potential of this site, a magnetotelluric (MT) survey was conducted, focusing on determining the depth distribution of the intrusive granite. The survey employed dimensionality analysis, utilizing Bahr skew and phase tensor analyses that denote a 2D subsurface nature up to 100 s and beyond that a 3D nature. In the present study, we interpreted MT data up to 100 s. The data collected, including rotated impedance tensors and tippers, were inverted using a nonlinear conjugate gradient algorithm integrated into the MT interpretation software of the WinG Link 2D inversion data modeling package. Multiple homogeneous half-space initial models were tested during the 2D inversion process. The findings indicate the existence of a midcrustal conductor associated with graphites and iron sulfides in the source region. This conductivity may be attributed to processes such as exsolution of metamorphic fluids, influx of mantle sources, or the entry of magmatic fluids through transcrustal fault zones. The findings indicate that the intrusive granite was emplaced along a NE–SW major fault, penetrating shallow crustal levels. The depth of this granite intrusion is determined to be 15 km, covering an outcrop area of 60 km². This detailed geological information allows a comprehensive assessment of the power-generating capacity of the intrusive granite. The results of this investigation contribute valuable insights for the development and optimization of Enhanced Geothermal System (EGS) projects in the region. © 2024, TUBITAK. All rights reserved.Article Citation - Scopus: 3Evaluation of Gis-Based Spatial Interpolation Methods for Groundwater Level: a Case Study of Türkiye(Tubitak Scientific & Technological Research Council Turkey, 2024) Kırçiçek, Nilüfer Tirol; Baba, Alper; Koçbay, Ayhan; Toklu, Murat MertGroundwater is a valuable and universally distributed resource on Earth. Understanding the spatial and temporal dynamics of groundwater is of utmost importance for effective management. Normally, groundwater levels are recorded at arbitrary points, but groundwater modeling requires interpolating the measured values at specific grid nodes. This study aims to dentify and evaluate the geographical variations of groundwater levels in Türkiye using three geostatistical interpolation techniques. Data from 355 groundwater wells from 1970 to 2019 were used for this purpose. In addition, an investigation of changes in annual average temperature and precipitation was conducted for two different time periods: 1985–2000 and 2001–2016. The results show an increase in the annual average temperature in Türkiye by 0.82 °C during the reference period (1985–2000). Despite regional differences in the precipitation regime, the average annual precipitation in Türkiye has not changed significantly overall. Especially in the Meriç-Ergene, Konya Closed (Konya Kapalı), and Euphrates-Tigris basins, a significant decrease in groundwater levels was observed, even though this decrease is less than 100 m in some wells. After a comprehensive analysis of all these data, possible explanations for the changes in groundwater levels were considered.Article Stochastic 1-D Reactive Transport Simulations To Assess Silica and Carbonate Phases During the $co_2$ Reinjection Process in Metasediments(TÜBİTAK - Türkiye Bilimsel ve Teknolojik Araştırma Kurumu, 2024) Erol, SelçukOne proposed method to mitigate carbon emission is to mineralize the $CO_2$ in deep geothermal reservoirs while mixing the coproduced CO2 with the effluent fluid for reinjection. The injection fluid temperature fluctuates due to the mixing process between CO2-charged water and the effluent fluid, and compressor interruptions change the thermodynamic conditions that influence the fluid- rock interaction in the reservoir. Mineral dissolution or precipitations are associated with changes in permeability and porosity that affect the flow and, eventually, the lifespan of the reservoir. A combined stochastic–reactive transport simulation approach is useful for inspection purposes. Moreover, the stochastic algorithm validates the deterministic reactive transport simulation and demonstrates the time evolution of a chemically reacting system in the reservoir. This study examines a range of injection temperatures between 80 °C and 120 °C to evaluate silica and calcite precipitation along a flow path. One-dimensional (1-D) reactive transport and compartment- based stochastic reaction-diffusion-advection Gillespie algorithms are carried out. The 1-D model represents a reservoir feed zone of around 2300 m. Two common metasediment rock types are evaluated for inspection. The first one is the muscovite schist, which has approximately 60% quartz, and the second is the quartz schist, consisting of roughly 90% quartz. The stochastic method can be applied more effectively if the chemical system is completely defined with proper reaction rates as a function of temperature. The mixing ratio of the coproduced $CO_2$ over the effluent fluid is around 0.0028. Simulation results show that $CO_2$ is partially sequestrated as calcite within the first 10 m of the entrance to the reservoir and plugs the pores completely in the muscovite schist scenario. Chalcedony and α-cristobalite precipitate as secondary minerals evenly along the flow path. $CO_2$ injection into a quartz schist layer is more appropriate for geochemical interactions below 120 °C.Article Citation - Scopus: 2Application of Endurance Time Method in Seismic Assessment of Rc Frames Designed by Direct Displacement-Based Procedure(Turkish Chamber of Civil Engineers, 2024) Karımzada, Nisar Ahmad; Shırkhanı, Amir; Aktaş, EnginThis paper addresses the Direct Displacement-Based Design (DDBD) approach of multi-story RC frame structures consistent with changes to design criteria between Turkish earthquake codes of TSC-2007 and TBEC-2018. The corresponding response modification factor (R) of structures designed based on the DDBD approach is also estimated in this research. The design base shear forces of both codes are compared considering different R factors and also with that of the DDBD approach. The results showed that the DDBD approach, as per TBEC-2018, provides RC frame structures with higher R values compared to the similar approach in accordance with TSC-2007. The Endurance Time (ET) method is a time history-based procedure for seismic assessment of structures under intensifying dynamic excitations aided to judge their performance at various intensity levels. Since, up to now, the ET method has not been considered to evaluate the performance of the structures designed by the DDBD approach, this paper addresses this issue. The ET performance curves of RC frames show that structures designed by the DDBD approach in accordance with TBEC-2018 exhibit higher Interstory Drift Ratios (IDRs) values than TSC-2007 at various hazard levels.Article Blank Frame and Intensity Variation Distortion Detection and Restoration Pipeline for Phase-Contrast Microscopy Time-Lapse Images(Aves, 2024) Ucar, Mahmut; Iheme, Leonardo O.; Onal, Sevgi; Pesen-Okvur, Devrim; Yalcin-Ozuysal, Ozden; Toreyin, Behcet U.; Unay, DevrimIn this study, we propose a preprocessing pipeline for the detection and correction of distorted frames in time-lapse images obtained from phase-contrast microscopy. The proposed pipeline employs the average intensities of frames as a foundational element for the analysis. In order to evaluate the degree of correction required for intensity variance, a normalization technique is applied to the difference between the average intensity of a specific frame and the median average intensity of all frames within the study. Our restoration method increases the histogram similarity between the distorted and non-distorted frames, preserves trans-passing pixels in regions of interest, and mitigates the development of additional distortions. The efficacy of the proposed method was evaluated using 15 395 time-lapse image frames from 27 experiments using our own dataset and 830 time-lapse images from four different experiments obtained from the cell tracking challenge. The results of the validation demonstrate a high degree of numerical and visual accuracy of the proposed pipeline.Article Citation - WoS: 2Citation - Scopus: 1A Review of the Geothermal System Evolution and Distribution in the Central Anatolian Crystalline Complex (türkiye)(TUBITAK, 2023) Şener, M.F.; Öztürk, M.Z.; Baba, A.Türkiye is located in the Mediterranean sector of the Alpine–Himalayan tectonic belt and is among the foremost seven countries in the world having an abundance of geothermal resources. The Central Anatolian Crystalline Complex (CACC) is one of the most important geothermal regions in Türkiye. This study aims to evaluate the geothermal system of CACC using the geological, structural, and hydrogeochemical properties that were obtained from previous studies. The present study investigated and evaluated the hydrogeochemical and isotopic properties of 762 water samples belonging to 45 different localities from 41 scientific studies. The result shows that CACC has different heat sources and different hydrogeochemical processes. Major element chemistry of the water reveals that the geothermal fluids are mostly of the Ca-Mg-HCO3, Na-Cl-HCO3, and Ca-Cl water types. Silica geothermometers suggest that the reservoir temperature ranges from 48 to 180 °C. Based on the δ18O-δD relationship, water samples have a high-altitude meteoric origin. Stable isotopic data indicate that the geothermal fluids are formed by local recharge and deep circulation of meteoric waters. © TÜBİTAK.