Chemical Engineering / Kimya Mühendisliği

Permanent URI for this collectionhttps://hdl.handle.net/11147/14

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Author: search.filters.author.Sofuoğlu, AysunSubject: search.filters.subject.Carcinogenic risk

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  • Article
    Citation - WoS: 303
    Citation - Scopus: 336
    A Health Risk Assessment for Exposure To Trace Metals Via Drinking Water Ingestion Pathway
    (Elsevier Ltd., 2009) Kavcar, Pınar; Sofuoğlu, Aysun; Sofuoğlu, Sait Cemil
    A health risk assessment was conducted for exposure to trace metals via drinking water ingestion pathway for Province of İzmir, Turkey. Concentrations of 11 trace metals were measured in drinking waters collected from 100 population weighted random sampling units (houses). The samples were analyzed in atomic absorption spectrometry for arsenic, and inductively coupled plasma-optical emission spectrometry for Be, Cd, Co, Cr, Cu, Mn, Ni, Pb, V, and Zn. Questionnaires were administered to a participant from each sampling unit to determine drinking water consumption related information and demographics. Exposure and risks were estimated for each individual by direct calculation, and for İzmir population by Monte Carlo simulation. Six trace metals (As, Cr, Cu, Mn, Ni, and Zn) were detected in >50% of the samples. Concentrations of As and Ni exceeded the corresponding standards in 20% and 58% of the samples, respectively. As a result, arsenic noncarcinogenic risks were higher than the level of concern for 19% of the population, whereas carcinogenic risks were >10-4 for 46%, and >10-6 for 90% of the population.
  • Article
    Citation - WoS: 74
    Citation - Scopus: 89
    Seasonal Variation in Drinking Water Concentrations of Disinfection By-Products in Izmir and Associated Human Health Risks
    (Elsevier Ltd., 2008) Baytak, Derya; Sofuoğlu, Aysun; İnal, Fikret; Sofuoğlu, Sait Cemil
    Seasonal variation in concentrations of two different disinfection by-product groups, trihalomethanes (THMs) and haloacetonitriles (HANs), was investigated in tap water samples collected from five sampling points (one groundwater and four surface water sources) in İzmir, Turkey. Estimates of previously published carcinogenic and non-carcinogenic risks through oral exposure to THMs were re-evaluated using a probabilistic approach that took the seasonal concentration variation into account. Chloroform, bromoform, dibromochloromethane and dichloroacetonitrile were the most frequently detected compounds. Among these, chloroform was detected with the highest concentrations ranging from 0.03 to 98.4 μg/L. In tap water, at the groundwater supplied sampling point, brominated species, bromoform and dibromoacetonitrile, were detected at the highest levels most probably due to bromide ion intrusion from seawater. The highest total THM and total HAN concentrations were detected in spring while the lowest in summer and fall. The annual average total THM concentration measured at one of the surface water supplied sampling points exceeded the USEPA's limit of 80 μg/L. While all non-carcinogenic risks due to exposure to THMs in İzmir drinking water were negligible, carcinogenic risk levels associated with bromodichloromethane and dibromochloromethane were higher than one in million.