Rectorate / Rektörlük
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Article Governing Authority Through Bureaucracy: Conflicts Over Bureaucratic Cadres and the Rise of Authoritarianism in the Late Ottoman Empire (1908-1913)(Routledge Journals, Taylor & Francis Ltd, 2024) İlter, MustafaThis article presents a historical analysis of how internal power struggles and conflicts among state actors can foster the development of authoritarian systems, particularly when a political network gains exclusive control over the bureaucratic apparatus through its authority over appointments and dismissals. Focusing on the intricate power struggles and factional rivalries surrounding gubernatorial appointments between 1908 and 1913, this article aims to provide an alternative approach to understanding how the Committee of Union and Progress (CUP) became the dominant governing force within the state apparatus, enabling it to pursue an authoritarian agenda.Article Ai-Assisted Survival Prediction in Colorectal Cancer: a Clinical Decision Support Tool(dergipark, 2021) Leblebici, Asım; Mısırlıoğlu, Hüseyin Koray; Koçal, Gizem Çalıbaşı; Ellidokuz, Hülya; Başpınar, YaseminPurpose: Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide. Accurate survival prediction is crucial for advanced-stage patients to optimize treatment strategies and improve clinical outcomes. This study aimed to develop an artificial intelligence-assisted clinical decision support system (CDSS) for survival prediction in CRC patients using clinical and genomic data from the Cancer Genome Atlas Colon Adenocarcinoma Collection (TCGA-COAD) dataset. Methods: Machine learning algorithms, including C4.5 Decision Tree, Support Vector Machines (SVM), Random Forest, and Naive Bayes, were employed to create survival prediction models. Clinical parameters and genomic data from key pathways, such as glycolysis/gluconeogenesis and mTORC1, were integrated into the models. The models were evaluated based on accuracy and performance. Results: The Random Forest algorithm achieved the highest accuracy (82.3%) when only clinical parameters were used. When clinical data were combined with gene expression data, the model’s accuracy increased further. The resulting models were incorporated into a user-friendly web interface, SurvCOCA, for clinical use. Conclusions: This study demonstrates the potential of AI-based tools to improve prognosis predictions in CRC patients. Further research is needed, with larger datasets and additional machine learning algorithms, to enhance clinical decision-making and optimize treatment strategies.Article General Purpose and Focused Invention, Market Value, and Productivity(2024) Dindaroğlu, BurakWe study returns to general purpose and focused invention at the firm level for a panel of manufacturing firms in the U.S. for the period 1976-1995, by studying their relationships with market value and Total Factor Productivity. We construct stocks of patents that lie at the two relevant tails of the distribution of the generality index (Trajtenberg et al., 1997; Henderson et al, 1998) to measure general purpose and focused invention at the firm level. In line with expectations, there is a market value premium to focused invention, and a productivity premium to general purpose invention. Estimates for the value of focus indicate that moving a single patent from the upper tail of the generality distribution to the lower tail would increase market value by .24×q million 1992 dollars on average, where q is Tobin’s q. The firm with the average general patent stock would gain 6.7×q million in market value if all its patents at the highest quartile of the generality distribution were moved to the lowest. In terms of the value of general purposeness, moving all its focused patents to the general category increases Total Factor Productivity by 2.3% to 2.8%, and five-year productivity growth by 3.9% to 5.2%, for the average firm. A potential implication is that corporate basic research is associated with significant long-term benefits in terms of productivity growth.Article An Empirical Study of Sequential Offer Bargaining During the Festival of Sacrifice(Elsevier, 2024) Dindaroğlu, Burak; Ertaç, SedaWe report results from a unique data set of real -life bargaining transactions collected from the market for livestock (sheep) before the Festival of Sacrifice (Eid al-Adha) in Izmir, Turkey. This market is characterized by frequent and aggressive bargaining, which occurs in the form of sequential price offers. We record bargaining transactions as they occur, and collect detailed information on the bargaining environment, as well as on the characteristics of buyers and sellers. We also elicit each seller's outside option by means of an incentive compatible mechanism and obtain a reported maximum willingness to pay from buyers. We particularly focus on aspects of the bargaining process, such as non -price communication. In different types of empirical analysis, results robustly indicate that the presence and content of communication matters, for the likelihood of a sale as well as concessions made. Specifically, buyer -side communication is associated with larger concessions from the seller and a higher probability of sale. The presence of a mediator during the negotiation is associated with a higher probability of sale as well, while it has no effect on prices. We also provide results on the relative importance of groups of variables for predicting bargaining outcomes, which can provide directions for further research in bargaining.Article Citation - WoS: 4Citation - Scopus: 2Unwanted Others of the City: Counter-Cultural Production of the Roma People of Urla-Turkey(Taylor & Francis, 2024) Uştuk, OzanThis article examines a case of urban displacement and its impact on the local Roma community by uncovering the discursive strategies of the local governments and the tactical responses of the local people. Based on two-year-long ethnographic research, this study aims to understand the intricate dynamics of the counter-cultural production of the Roma people as a response to gentrification policies of local governments. The rapid rise of the rent value of land has motivated the capital class to force an exile strategy on Roma and accelerated existing segregation policies. During this time, some discursive strategies to manufacture public consent about the gentrification have circulated to change the representation of the Roma identity, replacing their imagery in mainstream society by mainly signifying them as the undeserving poor. This research aims to understand how strategic discourses and actions have positioned Roma in the societal and cultural sphere and in response, how everyday tactics of the Roma engenders counter-cultural forms through intercultural communication.Article Citation - WoS: 2Citation - Scopus: 3Nkx3.1 Expression Contributes To Epithelial-Mesenchymal Transition of Prostate Cancer Cells(American Chemical Society, 2023) Saydullaeva, Iroda; Debeleç Bütüner, Bilge; Korkmaz, Kemal SamiStudies demonstrate that inflammation synergizes with highgrade aggressive prostate tumor development and ultimately metastatic spread, in which a lot of work has been done in recent years. However, the clear mechanism of inflammation inciting prostate cancer remains largely uncharacterized. Our previous study has shown that the conditioned media (CM)-mediated LNCaP cell migration is partially correlated with the loss of expression of the tumor suppressor NKX3.1. Here, we continue to investigate the inflammation-mediated migration of prostate cancer cells, and the role of NKX3.1 in this process to gain insights into cell migration-related changes comprehensively. Earlier, the model of inflammation in the tumor micro environment have been optimized by our research group; here, we continue to investigate the time-dependent effect of CM exposure together with NKX3.1 changes, in which we observed that these changes play important roles in gaining heterogeneous epithelial-to-mesenchymal transition (EMT) phenotype. Hence, this is an important parameter of tumor progression; we depleted NKX3.1 expression using the CRISPR/Cas9 system and examined the migrating cell clusters after exposure to inflammatory cytokines. We found that the migrated cells clearly demonstrate reversible loss of E-cadherin expression, which is consistent with subsequent vimentin expression alterations in comparison to control cells. Moreover, the data suggest that the AR mediated transcriptional program also contributes to mesenchymal-to-epithelial transition (MET) in prostate cancer progression. Furthermore, the quantitative proteomic analysis showed that migrated subpopulations from the same cell line presented different phenotypes in which the proteins overexpressed are involved in cell metabolism and RNA processing. According to KEGG pathway analysis, the ABC transporters were found to be the most significant. Thus, the dynamic process of cellular migration favors diverse genetic compositions under changing tumor microenvironments. The different levels of invasiveness are supported by shifting the cells in between these EMT and MET phenotypes.Article Citation - Scopus: 1İzmir'in bir dağ köyü: Yamanlar ve Yamanlar Yörükleri üzerine etnotarihsel bir inceleme(Rector CIU Cyprus int Univ, 2023) Ustuk, OzanThis study examines the history, language, social, and economic transformation of the Yuruks living in the Yamanlar Village located in the Karsiyaka district, where there is relatively little information in the literature despite its proximity to the Izmir city center. Information collected from the Ottoman Era cemetery adjoining the village reveals that the Yamanlar Yuruks have lived here for at least 400 years. Mount Yamanlar, where the village is located, is of great importance because of its ancient history, as it witnessed the founding of Izmir (Smyrna). The social and economic lifestyle in the village has transformed as the city expanded toward residential areas atop Mount Yamanlar. The loss of traditional livelihood practices challenged the villagers and severely influenced their customs, which might be considered valuable pieces of cultural heritage. In this study, we conducted fieldwork, during which various data collection methods and techniques were employed to describe daily life in the village. Within the scope of this study, semi-structured and unstructured interviews were conducted with the local people, and an oral historical study was carried out. With this method, we aimed to present an ethnohistorical description of the Yamanlar Village by trying to establish a balance between the analysis of both written documents and oral data to make sense of the social and economic change it has undergone and to contribute to the literature on Izmir Yuruks.Book Part Eu as a Good (enough) Governance Exporter in Kosovo? Local Views on the Aborted Kosovo E Re Power Plant Project(Springer, 2022) Buhari Gülmez, Didem; Aydın Dikmen, BengüThis study focuses on the EU's perceived role in Kosovo as a good governance exporter through political conditionality. Local debates on the EU's stance towards the recently aborted coal power plant project (Kosovo e Re) reflect a disappointment with the EU's failure to prioritise good governance reforms that have not been implemented sufficiently in Kosovo. The study mainly benefits from interviews conducted in Pristina in 2019 in order to explore various EU, domestic and international factors hindering the EU's capability as a good governance exporter. Following the EU's limited transformative agency in contested states, it concludes that the EU is perceived by local actors in Kosovo as a "good enough governance" exporter that favours stability in the region and transatlantic partnership at the expense of good governance reforms. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.Book Part Citation - Scopus: 1Field Experiments in Bargaining(Springer, 2022) Dindaroğlu, Burak; Ertaç, SedaUnderstanding price formation and surplus division in bargaining contexts has long been of interest to economists. Laboratory experiments contribute to our understanding of bargaining by inducing valuations and costs, which are usually unobserved in natural negotiation settings, and allow control over the negotiation process. Field experiments, on the other hand, allow economists to study bargaining in more natural contexts with higher external validity, and can be particularly useful when bargaining behavior draws on context-specific characteristics and experiences that may be stripped in lab settings or involves biases that would not surface under observability. In this chapter, we provide an overview of field experiments studying bargaining behavior and outcomes in a variety of settings, from bargaining for auto rickshaw to markets for livestock. We offer a methodological discussion, position field experiments in bargaining in the tradition of field experiments in economics at large, and highlight difficulties in the design and implementation of fieldwork for such environments. We also discuss potential areas and issues where future field experiments are of special importance for understanding price formation in bargaining. © The Editor(s) (if applicable) and The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022.Book Part Citation - Scopus: 1Destined for Coal?: a "hierarchy of Harms" and the Prospects of Renewable Energy in Kosovo(Springer, 2022) Aydın Dikmen, Bengü; Buhari Gülmez, DidemRelying on interviews conducted in the summer of 2019 with parliamentary advisors, civil society activists, public officials and the EU, OSCE, and UNDP missions in Kosovo, this study provides an overview of the debates about the building of the new coal power plant by a US-led (UK-based) Company ContourGlobal. It discusses how different actors in Kosovo state and society approach the renewable energy question. An important obstacle against Kosovo's transition to renewable energy derives from the absence of consensus about the main threats and goals facing Kosovo. In this context, rationalist and constructivist stances imply different "hierarchies of harms". © The Author(s), under exclusive license to Springer Nature Switzerland AG 2022. All rights reserved.