Materials Science and Engineering / Malzeme Bilimi ve Mühendisliği

Permanent URI for this collectionhttps://hdl.handle.net/11147/4719

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  • Article
    Citation - WoS: 18
    Citation - Scopus: 17
    Cnt Incorporated Polyacrilonitrile/Polypyrrole Nanofibers as Keratinocytes Scaffold
    (Trans Tech Publications, 2019) İnce Yardımcı, Atike; Aypek, Hande; Öztürk, Özgür; Yılmaz, Selahattin; Özçivici, Engin; Meşe, Gülistan; Selamet, Yusuf
    Polypyrrole (PPy) is an attractive scaffold material for tissue engineering with its non-toxic and electrically conductive properties. There has not been enough information about PPy usage in skin tissue engineering. The aim of this study is to investigate biocompatibility of polyacrilonitrile (PAN)/PPy nanofibrous scaffold for human keratinocytes. PAN/PPy bicomponent nanofibers were prepared by electrospinning, in various PPy concentrations and with carbon nanotube (CNT) incorporation. The average diameter of electrospun nanofibers decreased with increasing PPy concentration. Further, agglomerated CNTs caused beads and disordered parts on the surface of nanofibers. Biocompatibility of these PAN/PPy and PAN/PPy/CNT scaffolds were analyzed in vitro. Both scaffolds provided adhesion and proliferation of keratinocytes. Nanofiber diameter did not significantly influence the morphology of cells. However, with increasing number of cells, cells stayed among nanofibers and this affected their shape and size. In this study, we demonstrated that PAN/PPy and PAN/PPy/CNT scaffolds enabled the growth of keratinocytes, showing their biocompatibility.
  • Conference Object
    Microstructure-Performance Relation in Pmma-Based Open-Cell Porous Materials for High Pressure Ceramic Sanitaryware Casting
    (Trans Tech Publications, 2004) Ergün, Yelda; Dirier, C.; Yılmaz, M.; Tokman, C.; Tanoğlu, Metin
    The ceramic whiteware/sanitaryware industry is rapidly undergoing to implement high-pressure casting techniques for ceramic article production. In these techniques, materials with open pore microstructure that allows drainage of water under applied pressure are needed. The polymethyl methacrylate (PMMA) based polymeric porous materials have become the most suitable type of materials for this purpose because of their short casting periods and high service lives. However, the superior service life and performance of these materials are closely related to the microstructure. In the present study, the porous materials with various compositions of the constituents in the emulsion were produced to effect the microstructure of PMMA-based materials. The variations on the pore microstructure were interrelated to the performance of the material for high-pressure sanitaryware casting. The pore morphology and water permeability of the samples was measured using optical and SEM microscopy and permeability measurement techniques, respectively. The compressive collapse stress and modulus values were determined by performing compression testing. The results showed a significant interrelation between microstructure and the performance of the PMMA-based ceramic mould materials.