Materials Science and Engineering / Malzeme Bilimi ve Mühendisliği

Permanent URI for this collectionhttps://hdl.handle.net/11147/4719

Browse

Filters

2016 - 20182

Settings

Publisher: search.filters.publisher.John Wiley and Sons Inc.WoS Q: search.filters.wosQuartile.Q2

Search Results

Now showing 1 - 2 of 2
  • Article
    Citation - WoS: 56
    Citation - Scopus: 55
    A Bodipy-Based Fluorescent Probe To Visually Detect Phosgene: Toward the Development of a Handheld Phosgene Detector
    (John Wiley and Sons Inc., 2018) Sayar, Melike; Karakuş, Erman; Güner, Tuğrul; Yıldız, Büşra; Yıldız, Ümit Hakan; Emrullahoğlu, Mustafa
    A boron-dipyrromethene (BODIPY)-based fluorescent probe with a phosgene-specific reactive motif shows remarkable selectivity toward phosgene, in the presence of which the nonfluorescent dye rapidly transforms into a new structure and induces a fluorescent response clearly observable to the naked eye under ultraviolet light. Given that dynamic, a prototypical handheld phosgene detector with a promising sensing capability that expedites the detection of gaseous phosgene without sophisticated instrumentation was developed. The proposed method using the handheld detector involves a rapid response period suitable for issuing early warnings during emergency situations.
  • Article
    Citation - WoS: 6
    Citation - Scopus: 7
    Utilization of Electrospun Polystyrene Membranes as a Preliminary Step for Rapid Diagnosis
    (John Wiley and Sons Inc., 2016) Işık, Tuğba; Horzum, Nesrin; Yıldız, Ümit Hakan; Liedberg, Bo; Demir, Mustafa Muammer
    Recent advances in clinical practice drive deoxyribonucleic acid (DNA) as an important class of biomarker. Monitoring the change in their concentration suggests the initiation and/or progression of various disorders. However, low quantity of DNA biomarkers in body fluids requires a delicate isolation methodology that provides efficient separation and easy handling. This study describes a newer-generation separation technology relying on electrospun fibers of sub-micrometer diameter of a commodity polymer for DNA biomarkers in simulative serum. Fibrous polystyrene membranes are prepared by electrospinning and they are subjected to post-modification with Au. The composite membranes may provide a convenient environment for the removal of bovine serum albumin (BSA) from BSA and DNA mixtures. The eluent can be used as an efficient tool for detection of DNA biomarkers associated with diagnosis of numerous life-threatening diseases.