Electrical - Electronic Engineering / Elektrik - Elektronik Mühendisliği

Permanent URI for this collectionhttps://hdl.handle.net/11147/11

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Author: search.filters.author.Özgören, MuratPublisher: search.filters.publisher.Elsevier Ltd.

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  • Article
    Citation - WoS: 14
    Citation - Scopus: 18
    Separating Normosmic and Anosmic Patients Based on Entropy Evaluation of Olfactory Event-Related Potentials
    (Elsevier Ltd., 2019) Güdücü, Çağdaş; Olcay, Bilal Orkan; Schaefer, L.; Aziz, M.; Schriever, V. A.; Özgören, Murat; Hummel, T.
    Objective: Methods based on electroencephalography (EEG) are used to evaluate brain responses to odors which is challenging due to the relatively low signal-to-noise ratio. This is especially difficult in patients with olfactory loss. In the present study, we aim to establish a method to separate functionally anosmic and normosmic individuals by means of recordings of olfactory event-related potentials (OERP) using an automated tool. Therefore, Shannon entropy was adopted to examine the complexity of the averaged electrophysiological responses. Methods: A total of 102 participants received 60 rose-like odorous stimuli at an inter-stimulus interval of 10 s. Olfactory-related brain activity was investigated within three time-windows of equal length; pre-, during-, and post-stimulus. Results: Based on entropy analysis, patients were correctly diagnosed for anosmia with a 75% success rate. Conclusion: This novel approach can be expected to help clinicians to identify patients with anosmia or patients with early symptoms of neurodegenerative disorders. Significance: There is no automated diagnostic tool for anosmic and normosmic patients using OERP. However, detectability of OERP in patients with functional anosmia has been reported to be in the range of 50%.
  • Article
    Citation - WoS: 36
    Citation - Scopus: 44
    Continuous Time Wavelet Entropy of Auditory Evoked Potentials
    (Elsevier Ltd., 2010) Çek, Mehmet Emre; Özgören, Murat; Savacı, Ferit Acar
    In this paper, the continuous time wavelet entropy (CTWE) of auditory evoked potentials (AEP) has been characterized by evaluating the relative wavelet energies (RWE) in specified EEG frequency bands. Thus, the rapid variations of CTWE due to the auditory stimulation could be detected in post-stimulus time interval. This approach removes the probability of missing the information hidden in short time intervals. The discrete time and continuous time wavelet based wavelet entropy variations were compared on non-target and target AEP data. It was observed that CTWE can also be an alternative method to analyze entropy as a function of time. © 2009 Elsevier Ltd. All rights reserved.