Sürdürülebilir Yeşil Kampüs Koleksiyonu / Sustainable Green Campus Collection

Permanent URI for this collectionhttps://hdl.handle.net/11147/7755

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Now showing 1 - 4 of 4
  • Article
    Citation - WoS: 3
    Citation - Scopus: 3
    A Quality Assessment of Public Water Fountains and Relation To Human Health: a Case Study From Yozgat, Turkey
    (John Wiley and Sons Inc., 2019) İritaş, Servet Birgin; Türksoy, Vugar Ali; Deniz, Serdar; Koçoğlu, Serhat; Kırat, Güllü; Demirkesen, Ali Can; Baba, Alper
    Public fountains are very common and everyday people appreciate the benefits a water fountain can bring. However, consumption of public fountain water in some country has decreased because of growing concerns that constituents in fountain water may have adverse effects on health. A few studies have examined the safety of public fountains, proposing only limited evidence of fountain-related health issues in Turkey. Most of these public fountains are sourced from natural springs in Turkey. In this study, a 177 fountain water and 32 rock samples were analysed for source and quality of water. The geology of the region has the direct impact on the quality of the public fountain water. The results indicate that the level of some elements exceeded the limit values determined by WHO and US.EPA. The most striking high values were observed for iron (Fe), nickel (Ni), aluminum (Al), arsenic (As) and bromine (Br) concentrations.
  • Master Thesis
    Lab-on-a-chip devices for drug screening
    (Izmir Institute of Technology, 2019) Gökçe, Begüm; Pesen Okvur, Devrim; Çağır, Ali
    Breast cancer is one of the cancers with the highest incidence and mortality rates in women in Turkey as well as in the world. Tumor micro environment comprises of cancer and normal cells, extracellular matrix, soluble biological and chemical factors. Research has shown that cell shape, adhesion, migration, response to growth factors and drugs are different in 2D and 3D culture. Today, only 8 out of 100 anti-cancer clinical trial gives effective results. 3D cell culture systems have shown to be a necessary step between in vitro, in vivo and clinical studies. Therefore, it is necessary to better understand the interactions of cancer cells with their micro environment, for which new cell culture setups are required. The most apparent disadvantage of widely used 3D cell culture setups is the lack of stromal cells. The systems to be developed should both provide a 3D environment and comprise multiple cell types. The drug screen in 3D tri-culture method with a lab-on-a-chip device, that will be developed in this study will be able to answer these needs. Cell lines that represent different breast cancer types alone or together with stromal cells were cultured in 3D in the to be developed lab-on-a-chip; by determining the effects of drugs with different targets on the viability and distribution of cells, a drug screening method is developed.
  • Master Thesis
    Energy and Environmental Performance Based Decision Support Process for Early Design Stage of Residential Buildings
    (İzmir Institute of Technology, 2016) Gerçek, Mümine; Durmuş Arsan, Zeynep
    Deficiencies in systematic approaches for design decision support to increase energy and environmental performance of buildings in Turkey are projected as the major problem of this study. Rare usage of computational methods for evaluating and improving building performance, need for informational assistance in design, as well as lack of interaction between systematic knowledge and building practice are the secondary problems. This thesis mainly aims to test usability of the decision support process assisting architects in early design stages of residential buildings. Assessing the uncertainties in building performance caused by design parameters and climate change, in terms of determining the most significant parameters on annual energy consumption for heating, cooling and operational CO2 emissions in hot humid climatic region of Turkey is the significant objective of the study. The relation between input parameters and building performance indicators is examined by the uncertainty and global sensitivity analyses for a residential building in İzmir, Turkey. The process is supported by usability testing held with the architect in practice. The results indicate that, the sensitivity between input and output parameters changes according to the projected weather conditions and different floors of the building. The SHGC of windows on south-west, north-east facades, and window U values are the most effective parameters on energy and environmental performance. The proposed decision support process is approved to be applicable for early design stages of the selected building, and helps creating consciousness about the importance of systematic design decision approach for the building professional.
  • Master Thesis
    The Metaphor of "curtain Wall" in the Modern Architectural Discourse
    (Izmir Institute of Technology, 2013) Kutluay, Pınar; Yücel, Şebnem
    "Curtain wall" is mostly regarded as a direct outcome of the industrial reform in the Nineteenth Century. Following technological determinist approach, most of the studies about curtain wall seek to find an origin for it in the late Nineteenth Century. Different from these studies, this thesis investigates the formation of the discourse of curtain wall in view of its metaphoric background. Instead of focusing only on technology as the main factor, the study unveils different sides of the discourse which remained in the background and deciphers how "curtain," a term borrowed from textile and theatre, has been associated with facade of frame structure. In detail, the study sheds light on how frame structure, one of the main components of a curtain wall system, came to be called as "skeleton" with reference to the theory of organicism. The dressing --Bekleidung-- theory of Gottfried Semper is also examined as an alternative interpretation of the relationship between structure and facade regarding monumentalization through dressing and masking; as skeleton structure led architects to reconsider wall with concern of representation. Furthermore, the study concentrates on the architectural environment of Chicago in the second half of the Nineteenth Century, exploring two mainly different interpretations of frame structure which both arose from a shared concern of representation by some significant architects, including Louis H. Sullivan, who was also interested in monumentalization through ornament. This thesis claims that curtain wall is a metaphor invented to reconcile the emerging technology with the theory of representation which had diverse sides.